A5042621236- Hepatitis Viruses Studies and Epidemiology
- Viral gastroenteritis research and epidemiology
- Liver Disease and Transplantation
- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Liver Diseases and Immunity
- Bacteriophages and microbial interactions
- Cancer Immunotherapy and Biomarkers
- Computational Drug Discovery Methods
- Respiratory viral infections research
- COVID-19 diagnosis using AI
- Macrophage Migration Inhibitory Factor
- Animal Virus Infections Studies
- Neutropenia and Cancer Infections
- Immunotherapy and Immune Responses
- Viral Infections and Vectors
- Immunodeficiency and Autoimmune Disorders
- Research on Leishmaniasis Studies
- Biosensors and Analytical Detection
- Hepatitis C virus research
- Plant Virus Research Studies
- Blood disorders and treatments
- Salmonella and Campylobacter epidemiology
Universidad de Guadalajara
2018-2024
Hospital Civil de Guadalajara
2018-2021
Introduction The variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been classified into interest (VOIs) or concern (VOCs) to prioritize global monitoring and research on with potential risks public health. SARS-CoV-2 high-rate mutation can directly impact the clinical disease progression, epidemiological behavior, immune evasion, vaccine efficacy, transmission rates. Therefore, surveillance is crucial for controlling COVID-19 pandemic. In present study, we aimed...
SARS-CoV-2 has become a global pandemic due to its capacity for rapid transmission. In this context, an early and diagnosis of infected patients that do not require expensive equipment or highly trained personnel is crucial in order reduce the contagious rate. The aim study was evaluate chromatographic immunoassay's performance SARS-CoV-antigen.
To characterize the virological features of hepatitis E virus (HEV) in serum from patients exhibiting chronic liver damage.A data-base 513 unrelated individuals West-Mexico with liver-disease determined by clinical and biochemical tests transient elastography between 2011 2016 were retrospectively analyzed. According to infectious etiologies, classified as B (HBV)-, C (HCV)-infected patients, damage non-identified etiological agent (NIIEA). Available samples NIIEA-patients tested RT-nPCR for...
<b><i>Objective:</i></b> We aimed to detect and characterize hepatitis E virus (HEV) RNA in sera samples from a pediatric population infected with the A (HAV) exhibiting acute correlate infection status clinical outcome. <b><i>Methods:</i></b> Seventy-five ELISA-positive children containing anti-HAV anti-HEV IgM were used amplify partial regions within HEV ORF2. statistical comparison of data between IgM-positive/HEV RNA-positive patients...
Introduction Respiratory viral infections represent a significant global health burden. Historically, influenza, rhinovirus, respiratory syncytial virus, and adenovirus have been the prevalent viruses; however, landscape shifted with widespread emergence of SARS-CoV-2. The aim this study is to present comprehensive epidemiological analysis in Jalisco, Mexico. Methods Data encompassing individuals flu-like symptoms from July 2021 February 2023 was scrutinized for diagnosis through PCR...
The global distribution of hepatitis E virus (HEV) is attributed to its capacity spread through several routes transmission; hemodialysis has gained increased amounts attention in recent years. Although Mexico considered a hyperendemic region for E, no HEV surveillance performed the country. frequency (HD) patients not been determined. Herein, we conducted cross-sectional single-center analytical study including 67 serum samples from HD patients. Anti-HEV IgG and IgM antibodies viral genome...
Infection with hepatitis E virus (HEV) can cause acute and chronic in humans. The HEV genotype 3 be zoonotically transmitted from animals to humans, wild boars representing an important reservoir species. Cell culture isolation of is generally difficult mainly described for human isolates so far. Here, five sera liver samples HEV-RNA-positive boar were inoculated onto PLC/PRF/5 cells, incubated months thereafter passaged additional 6 weeks. As demonstrated by RT-qPCR, immunofluorescence...
Due to the COVID-19 pandemic, rapid development of vaccines against SARS-CoV-2 has been promoted. BNT162b2 is a lipid-nanoparticle mRNA vaccine with 95% efficacy and most administered globally. Nevertheless, little known about cellular immune response triggered by vaccination behavior over time. Therefore, we evaluated T-cell spike protein neutralization antibodies (nAbs) in naïve previously infected subjects vaccinated BTN162b2. Methods: Forty-six BTN162b2 were included (twenty-six twenty...
Hepatitis A virus (HAV) and hepatitis E (HEV) cause most of the global burden viral hepatitis. Geographical seasonal patterns contribute to epidemiological status infectious diseases. The extent these features in setting HAV HEV infections has not been analyzed detail. This point is important highly endemic countries both viruses, where pediatric population at high risk contracting infections. comparison between frequency antibodies RNA detection serum samples from patients with acute South...
We aimed to characterize the contribution of hepatitis E virus (HEV) in perpetuating cytokine-mediated inflammatory setting related liver damage context obesity. Herein, serum samples from patients with disease were retrospectively analyzed and categorized as normal-weight (NW), overweight (OW), obese (ObP), high alcohol consumer (HAC), biochemical, anthropometrical, transient elastography measurements obtained. The positivity for immunoglobulin M (IgM) G (IgG) anti-HEV antibodies was...
This study aimed to summarize the epidemiological and clinical characteristics of COVID-19 from Western Mexico people during 2020. A retrospective analysis an electronic database visiting a sentinel center for molecular SARS-CoV-2 confirmatory diagnosis by RT-PCR April December 2020 was carried out description COVID-19. Out 23,211 patients evaluated, 6918 (29.8%) were confirmed infection (mean age 38.5 ± 13.99), mostly females (53.8%). Comorbidities, such as diabetes (34.7%), obesity...
Abstract Background Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer in world, and myelotoxicities due to chemotherapy can lead severe infections hemorrhages with high morbidity mortality. The immune response has implications severity or survival. This associated predominant subpopulations CD4+ T cells their effector cytokines. However, it not known if responses are mortality children ALL. Methods To evaluate contributions immunological factors on ALL...
Based on high seroprevalence, null surveillance, and lack of diagnostics, Mexico is a high-risk region for hepatitis E Virus (HEV) infection. However, few local news infection are available. Clinicians general population in need increasing awareness, preventive measures should be emphasized.