A5038515561- Pharmaceutical Practices and Patient Outcomes
- Pharmacogenetics and Drug Metabolism
- Biomedical Text Mining and Ontologies
- Pharmaceutical studies and practices
- Opioid Use Disorder Treatment
- Genomics and Rare Diseases
- Electronic Health Records Systems
- Substance Abuse Treatment and Outcomes
- BRCA gene mutations in cancer
- Ethics in Clinical Research
- Lipoproteins and Cardiovascular Health
- Health Systems, Economic Evaluations, Quality of Life
- Patient Safety and Medication Errors
- Cannabis and Cannabinoid Research
- Health Policy Implementation Science
- Computational Drug Discovery Methods
- Family and Patient Care in Intensive Care Units
- Renal Diseases and Glomerulopathies
- Shoulder Injury and Treatment
- Adolescent and Pediatric Healthcare
- Pharmacy and Medical Practices
- Genetics, Bioinformatics, and Biomedical Research
- Geriatric Care and Nursing Homes
- Medication Adherence and Compliance
- Chronic Kidney Disease and Diabetes
Geisinger Health System
2021-2025
Center for Innovation
2024
Geisinger Medical Center
2022-2024
Genomic Health (United States)
2023-2024
HealthPartners
2022
University of Pittsburgh
2011-2021
BackgroundWe designed the Collaborative Approach to Reach Everyone with familial hypercholesterolemia (CARE-FH) clinical trial improve FH screening in primary care and facilitate guideline-based care.ObjectiveThe goal was incorporate perspectives from end-users (healthcare system leaders, clinicians, cardiologists, genetic counselors, nurses, clinic staff) translation of guidance into practice.MethodsWe partnered sequentially define current state screening, assess acceptability, feasibility,...
Objectives This substudy’s objectives were to (1) examine the transferability of a four archetype framework (simplified pattern prototypical features) for patients at high risk opioid use disorder (OUD) developed from previous study with similar population; (2) explore how patient preferences terminology can inform clinician communication strategies OUD across archetypes and (3) perceptions risks archetypes. Design qualitative collected data via semistructured phone interviews about views on...
Objective To understand home-care nurses’ perceptions of the post-hospitalisation information needs and communication problems older patients, how these factors might contribute to undesirable outcomes including poor patient reintegration into prior living environments unplanned hospital readmissions. Design A ranked list experienced by patients was developed two Nominal Group Technique (NGT) sessions from perspective nurses. The combined with results previously published work develop a...
Abstract Early identification of hereditary cancer predisposition in adolescents and young adults represents a unique opportunity to target prevention improve survival population at risk for adverse health outcomes. However, face challenges their stage life that can undermine transition from pediatric adult healthcare lead interruptions preventative care. The purpose this study was understand expert perspectives on factors relevant designing implementing clinic with predisposition. We used...
Background: Traceback testing—identifying and offering testing to people with previous cancer diagnoses who have not received current standard genetic testing—could benefit patients their at-risk relatives. Methods: We conducted a multisite, nonrandomized pilot implementation study of program at three integrated United States health systems. assessed the reach, fidelity, effectiveness, acceptability using quantitative qualitative methods. Results: identified 597 eligible individuals...
Background. Pharmacogenomic testing has the potential to improve safety and efficacy of pharmacotherapy, but clinical application pharmacogenetic knowledge remained uncommon. Clinical Decision Support (CDS) systems could help overcome some barriers implementation. The aim this study was evaluate perception usability a web- mobile-enabled CDS system for pharmacogenetics-guided drug therapy–the Medication Safety Code (MSC) system–among users (i.e., physicians pharmacists). Furthermore, sought...
The Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia (CARE-FH) study aims improve diagnostic evaluation rates for FH at Geisinger, an integrated health delivery system. This clinical trial relies upon implementation science transition the initial into primary care, attempting identify individuals prior onset of atherosclerotic cardiovascular disease events. protocol CARE-FH this paper is available online. first phase project focuses on design, including development...
Rationale & ObjectiveWhile the use of telemedicine has increased dramatically across disciplines, patient perspectives on related to chronic kidney disease are not well understood. We systematically reviewed qualitative studies patients with as those transplant better understand these patients' telemedicine.Study DesignQualitative Meta-AnalysisSetting Study ParticipantsPre-dialysis and that used telemedicine.Selection Criteria for StudiesEnglish language published in year 2000 beyond...
Despite the significant health impacts of adverse events associated with drug-drug interactions, no standard models exist for managing and sharing evidence describing potential interactions between medications. Minimal information have been used in other communities to establish community consensus around simple capable communicating useful information. This paper reports on a new minimal model interactions. A task force Semantic Web Health Care Life Sciences Community Group World-Wide...
A traceback genetic testing program for ovarian cancer has the potential to identify individuals with hereditary breast and their relatives. Successful implementation depends on understanding addressing experiences, barriers, preferences of people served.
Both patients and clinicians have described discussions of potential opioid risks as challenging. This study's goal was to understand patient perspectives on discussing with primary care (PCCs).Patients identified be at elevated risk for problems opioids (ie, use disorder [OUD] diagnosis, taking a medication OUD, or having ≥3 prescriptions in the last year) were recruited from an integrated, Upper Midwest health system participate semi-structured qualitative interviews. Interview questions...
To develop and evaluate a pharmacogenomics information resource for pharmacists.We built presenting Food Drug Administration (FDA) drug product labelling information, refined it based on feedback from pharmacists, conducted comparative usability evaluation, measuring task completion time, correctness perceived usability. Tasks involved hypothetical clinical situations requiring interpretation of to determine optimal prescribing specific patients.Pharmacists were better able perform certain...
The Computer Science, Biology, and Biomedical Informatics (CoSBBI) program was initiated in 2011 to expose the critical role of informatics biomedicine talented high school students.[1] By involving them Technology, Engineering, Math (STEM) training at level providing mentorship research opportunities throughout formative years their education, CoSBBI creates a infrastructure designed develop young informaticians. Our central premise is that trajectory necessary be an expert emerging fields...
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Abstract Background Genomic kidney conditions often have a long lag between onset of symptoms and diagnosis. To design real time genetic diagnosis process that meets the needs nephrologists, we need to understand current state, barriers, facilitators nephrologists other clinicians who treat experience, identify areas opportunity for improvement innovation. Methods Qualitative in-depth interviews were conducted with internists from 7 health systems. Rapid analysis identified themes in...
<sec> <title>BACKGROUND</title> Medical Marijuana (MMJ) is available in Pennsylvania and participation the state-regulated program requires a patient to register receive certification by an approved physician. There currently no integration of MMJ data into health records that would allow for physicians rapidly identify patients are using MMJ, as there with other scheduled drugs. This absence formal sharing structure necessitates tools aid consistent documentation practices enable...