A5100330457- Dental Implant Techniques and Outcomes
- Coronary Interventions and Diagnostics
- COVID-19 Clinical Research Studies
- Nanoplatforms for cancer theranostics
- Metabolomics and Mass Spectrometry Studies
- Bone Tissue Engineering Materials
- RNA Interference and Gene Delivery
- Acute Kidney Injury Research
- Antimicrobial Peptides and Activities
- SARS-CoV-2 and COVID-19 Research
- Adipose Tissue and Metabolism
- Cardiac Valve Diseases and Treatments
- Long-Term Effects of COVID-19
- Photoacoustic and Ultrasonic Imaging
- Cholesterol and Lipid Metabolism
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Heme Oxygenase-1 and Carbon Monoxide
- Connexins and lens biology
- Advancements in Photolithography Techniques
- Radiation Dose and Imaging
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cancer, Stress, Anesthesia, and Immune Response
Air Force Medical University
2013-2024
Xijing Hospital
2011-2024
Xi'an Medical University
2024
First Hospital of China Medical University
2020
China Medical University
2020
First Affiliated Hospital of Gannan Medical University
2015
Nanjing Medical University
2015
Jiangsu Province Hospital
2015
Second Affiliated Hospital of Zhejiang University
2015
It remains unknown whether the treatment of hypertension influences mortality patients diagnosed with coronavirus disease 2019 (COVID-19).
We previously showed that tanshinone IIA ameliorated the hypoxia-induced pulmonary hypertension (HPH) partially by attenuating artery remodeling. The proliferation of smooth muscle cells (PASMCs) is one major causes for arterial remodeling, therefore present study was performed to explore effects and underlying mechanism on PASMCs proliferation. were isolated from male Sprague-Dawley rats cultured in normoxic (21%) or hypoxic (3%) condition. Cell measured with 3 - (4, 5 dimethylthiazal 2 yl)...
To investigate the influence of sinus floor elevation (SFE) on physiology, including Schneiderian membrane thickness (MT) and ostium patency, using cone beam computed tomography (CBCT).Based pre-established selection criteria, 53 patients in combination with sinuses were referred for SFE a lateral approach deproteinized bone mineral. CBCT was performed prior to, immediately after surgery before staged implant placement. The MT elevated region, other clinical data evaluated.The two-stage...
<h3>Importance</h3> Left atrial appendage occlusion (LAAO) has emerged as an alternative to anticoagulation for patients with fibrillation. However, the performance of LAAO among East Asian is unknown. <h3>Objective</h3> To document procedural success rate and configurations, major adverse event rates, antithrombotic medication regimens during after procedures in China. <h3>Design, Setting, Participants</h3> In this cohort study, consecutive from 39 Chinese centers undergoing were...
Abstract Background Pulmonary hypertension (PH) is a progressive and fatal cardiopulmonary disease characterized by pulmonary vascular remodeling increased resistance artery pressure. Vascular associated with the excessive cell proliferation migration of smooth muscle cells (PASMCs). In this paper, effects heat shock protein-110 (HSP110) on PH were investigated. Methods The C57BL/6 mice human PASMCs (HPASMCs) respectively exposed to hypoxia establish simulate model in vivo experiment vitro....
The receptor for advanced glycation end products (RAGE) and thioredoxin (Trx) play opposing roles in diabetic myocardial ischemia-reperfusion (MI/R) injury. We recently demonstrated nitrative modification of Trx leads to its inactivation loss cardioprotection. present study is determine the relationship between augmented RAGE expression diminished activity pertaining exacerbated MI/R injury heart. state was induced mice by multiple intraperitoneal low-dose streptozotocin injections....
The complete excision of glioblastomas with maximal retention surrounding normal tissues can have a positive effect on the survival status and quality life patients. Near-infrared fluorescence (NIRF) optical imaging tumor vasculature offers noninvasive method for detection early stage glioblastoma efficient monitoring therapeutic responses. aim this study was to develop novel NIRF probe as visualization tool image-guided surgical resection orthotopic glioblastoma. In study, Cy5.5-RKL,...
Although several studies have found that metabotropic glutamate 5 receptor (mGluR5) may play an important role in autism spectrum disorders (ASD), the mechanisms remain unclear. Here, we used a Shank3 gene complete knockout mouse model (Shank3B-/-) to explore change mGluR5 brain. To assess whether deletion of mice results ASD-like behavior, conducted battery behavioral experiments characterize Shank3B-/- mice, including repetitive grooming behavior tests, three-chamber tests and...
Abstract Objectives We aimed to evaluate the safety and efficacy of Nano+™ (Lepu Medical, Beijing, China) stent implantation in all‐comer patients at 1‐year follow‐up. Background The is a novel polymer‐free sirolimus‐eluting polymer that employs nanoporous surface technology control drug‐delivery. one most widely used drug‐eluting (DES) China. Methods A total 2,481 consecutive were included multicenter prospective NANO registry. In this study, primary endpoint was target lesion failure (TLF)...
Abstract Purpose To investigate the feasibility of reducing healing time maxillary sinus floor elevation (MSFE) by a two‐stage approach using deproteinized bovine bone mineral (DBBM) alone, based on clinical, histomorphometric, and microradiographic evaluations. Materials Methods Twenty consecutive cases with an atrophic posterior edentulous maxilla were randomly assigned to two groups at ratio 1:1. The lateral window MSFE DBBM alone was followed 8‐month bone‐healing period in control group...
Cerenkov luminescence imaging offers a new diagnostic alternative to radiation imaging, but lacks intensity and penetration.In this study, signal its image quality were enhanced using rare earth oxide nanoparticles as basis for excited fluorescence tomography.The results also provided 3D-imaging quantitative information.The approach was evaluated phantom mice models 3D reconstruction studies performed in vitro, showing improved optical intensity, similarity, accuracy, signal-to-noise ratio,...
This study aimed to use the stretched-exponential nonlinear regression analysis model explore value of energy spectral curve in differential diagnosis clear cell renal carcinoma (ccRCC), minimal fat angiomyolipoma (RAML), and hypovascular carcinoma.Sixty-five cases with tumors were enrolled retrospectively who had undergone a preoperative multiphase CT scan kidney pre-enhance double-phase enhanced scanning. The normalized iodine concentrations (NIC) these lesions, normal cortex, psoas major...
Contrast-induced nephropathy (CIN) is one of major and serious complications in patients undergoing percutaneous coronary intervention (PCI). It unknown whether increased urinary adiponectin (UAPN), a sensitive marker for early renal function impairment, associated with an risk CIN. Therefore, we prospectively investigate the association UAPN We enrolled 208 who were elective PCI. The baseline was assessed prior to ROC analysis used evaluate predictive value Multivariate logistic regression...
BACKGROUND The risk factors for mortality of COVID-19 classified as critical type have not been well described. OBJECTIVES This study aimed to described the clinical outcomes and further explored in-hospital death type. METHODS was a single-center retrospective cohort study. From February 5, 2020 March 4, 2020, 98 consecutive patients were included in Huo Shen Shan Hospital. final date follow-up 29, 2020. primary outcome all-cause during hospitalization. Multivariable Cox regression model...
The optimal anticoagulation regimen for continuous renal replacement therapy (CRRT) in liver failure (LF) patients without increased bleeding risk remains controversial. Therefore, we conducted a monocentric retrospective study to evaluate the efficacy and safety of regional citrate (RCA) versus low molecular weight heparin (LMWH) CRRT LF risk.
Abstract Objectives To evaluate the 3-year clinical outcomes of a polymer-free sirolimus-eluting, Nano plus stent for treatment coronary artery disease in NANO multicenter Registry. Background The long-term data evaluating safety and efficacy novel sirolimus-eluting (Lepu Medical, Beijing, China) is limited. Methods all-comers Registry trial was prospective, registry conducted 26 centers China between August 2016 January 2017. A total 2481 consecutive patients were exclusively treated with...
Metal 3D printing has been used in the manufacturing of dental implants. Its technical advantages include high material utilization and capacity to form arbitrarily complex structures. However, alone is insufficient for two-stage titanium implants due limited precision alloy parts. In this study, was employed create implant structure, subsequently complemented by mechanical processing refine abutment connection neck. Additionally, properties 3D-printed were evaluated through tensile dynamic...