A5101497721- Dental Research and COVID-19
- Analytical Chemistry and Chromatography
- Metabolomics and Mass Spectrometry Studies
- Immune Response and Inflammation
- Oral microbiology and periodontitis research
- Phagocytosis and Immune Regulation
- Immune Cell Function and Interaction
- Erythrocyte Function and Pathophysiology
- Infection Control in Healthcare
- Gut microbiota and health
- Oral Health Pathology and Treatment
- Antimicrobial Peptides and Activities
- Mass Spectrometry Techniques and Applications
- Atmospheric chemistry and aerosols
- Infection Control and Ventilation
- Reproductive System and Pregnancy
- Dental Radiography and Imaging
- CAR-T cell therapy research
- Enzyme Catalysis and Immobilization
- Innovations in Medical Education
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Sepsis Diagnosis and Treatment
- Environmental and Industrial Safety
National Clinical Research Center for Digestive Diseases
2020-2025
National Medical Products Administration
2025
Peking University
2009-2025
Guizhou University
2025
Affiliated Hospital of Guizhou Medical University
2025
Xuzhou Medical College
2025
Wuhan University
2020-2024
Wuhan Textile University
2024
Stomatology Hospital
2009-2021
Medical University of Vienna
2021
Concentrated growth factor (CGF), a new generation of platelet concentrate product, appears to have more abundant factors because its special centrifugation process. However, there are few studies supporting this. This study was designed evaluate the contents major in CGF and compare them with those found PRP (platelet-rich plasma) PRF fibrin). PRP, PRF, were obtained from same samples peripheral blood. Concentrations five representative platelets measured enzyme-linked immunosorbent assay...
This epidemiological study leverages data from the Global Burden of Disease (GBD) database spanning 1990 to 2021 analyze global burden oral cancer. The research aims provide a comprehensive assessment age-standardized incidence rate (ASIR), mortality (ASDR), and disability-adjusted life years (DALYs) for cancer, examining trends over three decades. used age standardized (ASRs) as an indicator cancer data. Trend analysis uses estimated annual percentage change (EAPC) track changes in...
Dental healthcare workers (DHCWs) are at high risk of occupational exposure to droplets and aerosol particles emitted from patients' mouths during treatment. We evaluated the effectiveness an air cleaner in reducing droplet contamination by positioning device four different locations actual dental clinic. applied computational fluid dynamics (CFD) methods solve governing equations airflow, energy dispersion different-sized airborne droplets/aerosol particles. In a clinic, we measured supply...
Hydroxymethanesulfonate (HMS), the product of HSO3– and SO32– reacting with dissolved formaldehyde in fog, cloud, aerosol liquid water, has been suggested to be an important source particulate sulfur during haze events. However, there have limited studies high concentrations HMS atmospheric aerosol. We report here two feasible analytical methods for identification using ion chromatography UHPLC-LTQ-Orbitrap mass spectrometry. The fine particles wintertime Beijing ranged from below detection...
This study aimed to investigate the relationship between sleep duration and myopia in school-age students, as well observe role of physical activity a mediating variable myopia. Using multistage stratified sampling, 26,020 students Jiangsu Province, ages 7-18, were selected for this cross-sectional survey. Each participant completed standardized interview which their asked about vision, level average hours per day over past month. Visual acuity examinations conducted by testing team's...
ABSTRACT Purpose/Objectives The purpose of this study was to evaluate the effects digital–conventional integrated teaching method on prosthetics preclinically in full crown preparation courses. Methods Fifty‐eight undergraduate dental students were randomly divided into a conventional group (CG) and (DG). preclinical course composed two phases. In first phase, from both groups trained with method. second CG still method, whereas DG practiced digital real‐time training evaluation system. test...
Factors associated with outcomes of chimeric antigen receptor (CAR)-T cell therapy in patients relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) have not been fully elucidated. We explored the impact prelymphodepletion (pre-LD) lymphocyte to monocyte ratio (LMR) and its lactate dehydrogenase (LDH) (LMR/LDH) on efficacy prognosis 60 R/R DLBCL undergoing CAR-T therapy. The optimal cutoff values for pre-LD LMR LMR/LDH were 3.583 0.0103, respectively. overall response rate...
In-source fragmentation-based high-resolution mass spectrometry (ISF-HRMS) is a potential analytical technique, which usually used to profile some specific compounds that can generate diagnostic neutral loss (NL) or fragment ion (FI) in source inherently. However, the ISF-HRMS method does not work for those cannot inherently produce NL FI source. In this study, derivatization-based in-source fragmentation-information-dependent acquisition (DISF-IDA) strategy was proposed profiling...
Smoking is considered a significant risk factor for both periodontal disease and cardiovascular (CVD). Endothelial cells play an important role in the progression of diseases. In present study, we investigated vitro impact nicotine on functional properties human umbilical vein endothelial (HUVECs) stimulated with lipopolysaccharide (LPS) pathogen Porphyromonas gingivalis. HUVECs were different concentrations (10 µM-10 mM) and/or P. gingivalis LPS. Expression levels intercellular adhesion...
Peak alignment is a crucial step in liquid chromatography-mass spectrometry (LC-MS)-based large-scale untargeted metabolomics workflows, as it enables the integration of metabolite peaks across multiple samples, which essential for accurate data interpretation. Slight differences or fluctuations chromatographic separation conditions, however, can cause retention time (RT) shift between consecutive analyses, ultimately affecting accuracy peak samples. Here, we introduce novel RT correction...
Abstract Many traditional Chinese medicines have been used as immunomodulators that act either immunosuppressants or immunostimulators. Recently, our lab successfully isolated a monomer telocinobufagin (TCB) from the chloroform extract of Chan Su ( Venenum Bufonis ). In present paper, we evaluated immunomodulatory effects this compound in vitro. We found TCB significantly stimulates splenocyte proliferation when administered alone combination with polyclonal T‐cell mitogens concanavalin A...
Abstract Correlation between periodontitis and atherosclerosis is well established, the inherent mechanisms responsible for this relationship remain unclear. The biological function of growth arrest‐specific 6 (gas6) has been discovered in both inflammation. Inhibitory effects gas6 on expression inflammatory factors human umbilical vein endothelial cells (HUVECs) stimulated by Porphyromonas gingivalis lipopolysaccharide ( P. ‐LPS) were reported our previous research. Herein,...
Smoking is a well-recognized risk factor for oral mucosal and periodontal diseases. Nicotine an important component of cigarette smoke. This study aims to investigate the impact nicotine on viability inflammatory mediator production epithelial cell line in presence various stimuli. Oral HSC-2 cells were challenged with (10-8-10-2 M) 24 h or absence Porphyromonas gingivalis lipopolysaccharide (LPS, 1 µg/mL) tumor necrosis (TNF)-α (10-7 h. The proliferation/viability was determined by MTT...
Dental students are particularly vulnerable for needlestick injuries (NSI). However, the epidemiology of NSI exposures among Chinese dental was rarely reported. The objectives this study were to determine prevalence in a major teaching institution China, and identify associated factors.A self-administrated online questionnaire developed based on previously published studies, distributed Class 2011-2015 recruited from Peking University School Hospital Stomatology.Two hundred sixty-eight...
Abstract Background Dental interns are vulnerable to needlestick injuries (NSI). The objectives of this study were examine the prevalence and characteristics NSI exposures among dental during their first-year clinical training, assess risk factors, evaluate reporting behaviours. Methods An online survey was conducted Class 2011–2017 at Peking University School Hospital Stomatology (PKUSS), China. self-administrated questionnaire consisted information on demographic profiles, characteristics,...