A5017642425- Sleep and Wakefulness Research
- Sleep and related disorders
- Neuroscience of respiration and sleep
- EEG and Brain-Computer Interfaces
- Restless Legs Syndrome Research
- Epilepsy research and treatment
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Neuroscience and Music Perception
- Hearing, Cochlea, Tinnitus, Genetics
- Obstructive Sleep Apnea Research
- Mitochondrial Function and Pathology
- Long-Term Effects of COVID-19
- Stress and Burnout Research
- Eating Disorders and Behaviors
- Circadian rhythm and melatonin
- Heart Rate Variability and Autonomic Control
- Neural dynamics and brain function
- Vestibular and auditory disorders
- Glycogen Storage Diseases and Myoclonus
- Neuroscience and Neuropharmacology Research
- Health and Wellbeing Research
- Children's Physical and Motor Development
- Psychosomatic Disorders and Their Treatments
- Metabolism and Genetic Disorders
Azienda USL di Bologna
2021-2025
University of Bologna
2017-2021
Ospedale Bellaria
2019
Institute of Neurological Sciences
2018
University of Verona
2018
Introduction: Disorders of Arousal (DoA) are NREM parasomnias that have been typically regarded as self-limited childhood manifestations. It is now clear DoA can persist in adults, often presenting with distinctive characteristics. So far, few studies described the clinical course and characteristics adulthood, therefore a large part their semiology ignored. The aim this study to describe manifestations an adult population provide pathophysiological interpretation features. Methods: We...
Abstract Objective Disorders of arousal (DoA) are characterized by an intermediate state between wakefulness and deep sleep, leading to incomplete awakenings from NREM sleep. Multimodal studies have shown subtle neurophysiologic alterations even during in DoA. The aim this study was explore the brain functional connectivity DoA metabolic profile anterior posterior cingulate cortex, given its pivotal role cognitive emotional processing. Methods Fifteen consecutive patients with (9 males, mean...
Isolated REM sleep behavior disorder (iRBD) is a prodromal state of α-synucleinopathies, presenting years before overt neurodegenerative disorders. Autonomic nervous system (ANS) involvement, particularly cardiovascular autonomic failure, may indicate progression. However, its role as (multidimensional) marker for disease progression and phenoconversion remains unclear. This study aimed to investigate whether failure symptoms dysfunction serve multidimensional markers in patients with iRBD....
The differential diagnosis between sleep-related hypermotor epilepsy (SHE) and disorders of arousal (DOA) may be challenging. We analyzed the stage relative time occurrence parasomnic epileptic events to test their potential diagnostic accuracy as criteria discriminate SHE from DOA. Video-polysomnography recordings 89 patients with a definite DOA (59) or (30) were reviewed define major minor analyze occurrence. "event distribution index" was defined on basis during first versus second part...
Abstract Disorders of Arousal (DOA) are mental and motor behaviors arising from NREM sleep. They comprise a spectrum manifestations increasing intensity confusional arousals to sleep terrors sleepwalking. Although DOA in childhood usually harmless, adulthood they often associated with injurious or violent the patient others. Driving vehicles, suspected suicide, even homicide attempted have been described during sleepwalking adults. Furthermore, adult need be differentiated other disorders...
Abstract Objective Sleep‐related hypermotor epilepsy (SHE) is a focal characterized by seizures occurring mostly during sleep, ranging from brief with paroxysmal arousals (SPAs) to hyperkinetic and ambulatory behaviors. SPAs are stereotypic representing the beginning of major seizure. Distinguishing disorders arousal (DOAs) their briefest episodes called simple movements (SAMs) difficult. We performed characterization SAMs identify video‐polysomnographic (VPSG) features that can contribute...
Night terrors, sleepwalking and confusional arousals are behavioral manifestations of incomplete awakenings from sleep. According to international diagnostic criteria, these behaviors occur in the absence any mental experience, or presence very limited cognition dream imagery (eg, a single visual scene). The aim this study was systematically retrospectively investigate content associated with sleep terrors and/or both children adults.Forty-five consecutive patients referred for diagnosis...
Purpose: Disorders of arousal (DoA) are characterized by incomplete awakening from NREM sleep, with the admixture both deep sleep and wake EEG activity. Previous observations suggested that changes in activity could be detected seconds preceding DoA episodes. The aims this work were to characterize topography spectral prior episodes investigate whether or not behavioral complexity predicted immediately onsets. Patients Methods: We collected 103 consecutive video-polysomnographic recordings...
Abstract Study Objectives To define sleep-related movements in healthy adults according to sex and age. Methods Sleep-related from 50 video-polysomnography (vPSG) recordings of 27 men 23 women, 20 70 years old, were classified International classification sleep disorders (ICSD-3-TR) American Academy Sleep Medicine (AASM) criteria (codified movements); the remaining (non-codified movements) described type (elementary movements-EMs or complex movements-CMs), topography (focal, segmental,...
To describe clinical and video-polysomnographic features of disorders arousal (DoA) in older adults.Four consecutive male patients with nocturnal motor behaviors underwent a interview, neurologic examination, laboratory tests, brain magnetic resonance imaging, in-laboratory or 24- to 48-hour home video polysomnography. The repeated an evaluation after 6 months follow-up, including polysomnography 2 patients.The were aged 65-72 years, 1 patient has Parkinson disease. Sleep-related behavioral...
Fixation-off sensitivity (FOS) refers to seizures or EEG abnormalities elicited by the elimination of central vision/fixation, even in presence light.1 Typically, a paroxysmal discharge occurs within 1–3 seconds eye closure, persists throughout eye-closed state, and disappears immediately on opening.2