A5028131223- Sleep and Wakefulness Research
- Sleep and related disorders
- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Restless Legs Syndrome Research
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects and Toxicity Studies
- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Neuroscience of respiration and sleep
- Circadian rhythm and melatonin
- Autoimmune Neurological Disorders and Treatments
- Glycogen Storage Diseases and Myoclonus
- Autism Spectrum Disorder Research
- Functional Brain Connectivity Studies
- Genetics and Neurodevelopmental Disorders
- Genomic variations and chromosomal abnormalities
- Children's Physical and Motor Development
- Heart Rate Variability and Autonomic Control
- Neuroscience and Music Perception
- Bacterial Infections and Vaccines
- Neonatal and fetal brain pathology
- Genetic Neurodegenerative Diseases
- Infectious Encephalopathies and Encephalitis
- Migraine and Headache Studies
University of Bologna
2014-2025
Istituto delle Scienze Neurologiche di Bologna
2014-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2025
University of Catania
2016-2021
Assistance Publique – Hôpitaux de Paris
2019-2020
Pitié-Salpêtrière Hospital
2019-2020
Sorbonne Université
2019-2020
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2016
Headache and epilepsy are two relatively common neurological disorders their relationship is still a matter of debate. Our aim was to estimate the prevalence clinical features inter-ictal (inter-IH) peri-ictal headache (peri-IH) in patients with epilepsy. All aged ≥ 17 years referring our tertiary Epilepsy Centre were consecutively recruited from March May 2011 July 2012. They underwent semi-structured interview including International Classification Disorders (ICHD-II) criteria diagnose...
Abstract Objective Disorders of arousal (DoA) are characterized by an intermediate state between wakefulness and deep sleep, leading to incomplete awakenings from NREM sleep. Multimodal studies have shown subtle neurophysiologic alterations even during in DoA. The aim this study was explore the brain functional connectivity DoA metabolic profile anterior posterior cingulate cortex, given its pivotal role cognitive emotional processing. Methods Fifteen consecutive patients with (9 males, mean...
Isolated REM sleep behavior disorder (iRBD) is a prodromal state of α-synucleinopathies, presenting years before overt neurodegenerative disorders. Autonomic nervous system (ANS) involvement, particularly cardiovascular autonomic failure, may indicate progression. However, its role as (multidimensional) marker for disease progression and phenoconversion remains unclear. This study aimed to investigate whether failure symptoms dysfunction serve multidimensional markers in patients with iRBD....
To determine the polysomnography characteristics during sleep paralysis, false awakenings, and lucid dreaming (which are states intermediate to rapid eye movement [REM] wake but exceptionally observed in laboratory).In 5 participants, we captured episodes of paralysis (2 time marked with ocular left-right-left-right code normally used signal dreaming, 1 by an external noise, 2 retrospectively reported) awakening. The coding (using 3-second mini-epochs) spectral electroencephalography...
Eyelid myoclonia with absences (EMA) is a syndrome characterized by eyelid or without absences, eye closure-induced generalized electroencephalographic (EEG) paroxysms and photosensitivity. Few data are available about the prognostic factors of this syndrome. The main objectives our study were to describe clinical EEG features group patients EMA evaluate presence factors.We retrospectively selected cohort diagnosis evaluated in epilepsy service Neurological Clinic Catania, Neurology Clinical...
Abstract Study Objectives To define sleep-related movements in healthy adults according to sex and age. Methods Sleep-related from 50 video-polysomnography (vPSG) recordings of 27 men 23 women, 20 70 years old, were classified International classification sleep disorders (ICSD-3-TR) American Academy Sleep Medicine (AASM) criteria (codified movements); the remaining (non-codified movements) described type (elementary movements-EMs or complex movements-CMs), topography (focal, segmental,...
Purpose: Disorders of arousal (DoA) are characterized by incomplete awakening from NREM sleep, with the admixture both deep sleep and wake EEG activity. Previous observations suggested that changes in activity could be detected seconds preceding DoA episodes. The aims this work were to characterize topography spectral prior episodes investigate whether or not behavioral complexity predicted immediately onsets. Patients Methods: We collected 103 consecutive video-polysomnographic recordings...
To describe the anatomo-electro-clinical findings of patients with nocturnal hypermotor seizures (NHS) preceded by auditory symptoms, to evaluate localizing value aura.Our database 165 frontal lobe epilepsy (NFLE) diagnosis confirmed videopolysomnography (VPSG) was reviewed, selecting those who reported an aura as initial ictal symptom in at least two NHS during their lifetime.Eleven were selected (seven males, four females). According data, three groups identified. Group 1 [defined...
Sleepwalking is a disorder characterized by complex motor behaviors arising from slow wave sleep usually occurring in children. The adult onset of sleepwalking suggests the presence an external precipitating factor leading to occurrence disorder. Hyperthyroidism has been reported be possible cause few cases. We present case 36-year-old man who sudden appearance nocturnal episodes sleepwalking. He underwent complete video polysomnography (VPSG), which showed polygraphic pattern stage N3...
It is well known that sleep-related motor seizures can originate from the temporal lobe. However, little about clinical features of minor manifestations during sleep in patients with lobe epilepsy. The main objective our study was to verify existence events mesial epilepsy (MTLE) and define their electroencephalography (EEG) correlations.We enrolled diagnosis symptomatic MTLE a group healthy controls. All controls underwent long-term video -EEG monitoring, including at least one night...
To describe clinical and video-polysomnographic features of disorders arousal (DoA) in older adults.Four consecutive male patients with nocturnal motor behaviors underwent a interview, neurologic examination, laboratory tests, brain magnetic resonance imaging, in-laboratory or 24- to 48-hour home video polysomnography. The repeated an evaluation after 6 months follow-up, including polysomnography 2 patients.The were aged 65-72 years, 1 patient has Parkinson disease. Sleep-related behavioral...
The association between hereditary myotonic disorders and epilepsy is seldom described in the literature. To date, few reports have dealt with dystrophic myotonias, whereas a single case demonstrating an sporadic congenital myotonia was recently reported patient carrying de novo mutation of CLCN1 gene. Additional evidence for role pathogenesis derived from large‐scale exome analysis ion channel variants expression studies. Here, we describe first familial Thomsen epilepsy. All affected...