A5091855500- Seaweed-derived Bioactive Compounds
- Nanocomposite Films for Food Packaging
- Microbial Natural Products and Biosynthesis
- Postharvest Quality and Shelf Life Management
- Tuberculosis Research and Epidemiology
- Echinoderm biology and ecology
- Mycobacterium research and diagnosis
- Marine Sponges and Natural Products
- Marine and coastal plant biology
- Fungal Biology and Applications
- Essential Oils and Antimicrobial Activity
- Botanical Research and Applications
- Plant Physiology and Cultivation Studies
- Material Properties and Applications
- Algal biology and biofuel production
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Microbial Metabolism and Applications
- Molecular Sensors and Ion Detection
- Infectious Diseases and Tuberculosis
- Diagnosis and treatment of tuberculosis
- Food Quality and Safety Studies
- Synthesis of Organic Compounds
- Alkaloids: synthesis and pharmacology
- Synthesis and Reactivity of Sulfur-Containing Compounds
Kyushu University
2021-2025
Vietnam Academy of Science and Technology
2015-2024
Agricultural Genetics Institute
2024
Stanford University
2006-2023
Vietnam Academy of Agricultural Sciences
2023
Thai Nguyen University
2020-2023
Tay Nguyen University
2023
VNU University of Science
2017-2023
Nha Trang University
2015-2022
Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences
2020
Mycobacterium tuberculosis remains a major cause of morbidity and mortality worldwide. Studies have reported human pathogens to geographically structured population genetics, some which been linked ancient migrations. However, no study has addressed the potential evolutionary consequences such longstanding human-pathogen associations. Here, we demonstrate that global structure M. is defined by six phylogeographical lineages, each associated with specific, sympatric populations. In an urban...
Mathematical models predict that the future of multidrug-resistant tuberculosis epidemic will depend on fitness cost drug resistance. We show in laboratory-derived mutants Mycobacterium tuberculosis, rifampin resistance is universally associated with a competitive and this determined by specific mutation strain genetic background. In contrast, we demonstrate prolonged patient treatment can result strains no defect low- or no-cost mutations are also most frequent among clinical isolates.
Background. Treatment initiation rapidly kills most drug-susceptible Mycobacterium tuberculosis, but a bacterial subpopulation tolerates prolonged drug exposure. We evaluated drug-tolerant bacilli in human sputum by comparing messenger RNA (mRNA) expression of that survive the early bactericidal phase with treatment-naive bacilli. Methods. M. tuberculosis gene was quantified via reverse-transcription polymerase chain reaction serial sputa from 17 Ugandans treated for pulmonary tuberculosis....
In this study, development of bioactive coatings containing 1 % (w/v) chitosan (CS), 0.6 diepoxy-polyethylene glycol (PEG), and trans-cinnamaldehyde (CIN) was achieved. The physicochemical biological properties the were investigated. tensile strength, light transmission, water vapor permeability (WVP), antibacterial enhanced by incorporation CIN. CIN-containing films appeared compact rough, as observed using scanning electron microscopy (SEM) atomic force (AFM). addition, quality attributes...
Five new sesterterpenes, 14,15-dehydro-6-epi-ophiobolin K (1), 14,15-dehydro- ophiobolin (2), G (3), 14,15-dehydro-ophiobolin (4) and 14,15-dehydro-(Z)-14-ophiobolin (5), together with four known ophiobolins (6-9) were isolated from the marine fungus Aspergillus flocculosus derived seaweed Padina sp. collected in Vietnam. The five first as derivatives consisting of a fully unsaturated side chain. Their structures elucidated via spectroscopic methods including 1D, 2D NMR HR-ESIMS. absolute...
Genomic deletion analysis revealed that strains of Mycobacterium tuberculosis exhibiting spoligotyping patterns with almost all spacers present belong either to a strain lineage includes the W-Beijing family or ancestral M. tuberculosis.
AbstractThe aim of this study is to elucidate the structure and investigate hypolipidaemic activity a fucoidan extracted from brown seaweed Sargassum henslowianum collected at Hai Van–Son Cha peninsula, Hue province, Vietnam by using tandem electrospray ionisation mass spectrometry. The results demonstrated that has α(1 → 3)-linked l-fucopyranose backbone sulphate groups occupied mostly C-2, C-4 sometimes C-3 position fucose residues. in vivo bioactivity examination revealed dose 100...
Abstract The application of edible coatings to dried products such as silkworms ( Bombyx mori ) is an innovative method for preserving nutrients during drying process. These are made from safe, natural ingredients carboxymethylcellulose (CMC), nano cellulose fibre (NCF), chitosan (N-Ch), and varying concentrations green pomelo peel essential oil (GPO). results revealed that the addition GPO into coating/film significantly changed pH, viscosity, TSS values coating solutions while reducing...
Fucoidans from brown macroalgae have beneficial biomedical properties but their use as pharma products requires homogenous oligomeric products. In this study, the action of five recombinant microbial fucoidan degrading enzymes were evaluated on fucoidans macroalgae:
The metabolic profile of the Aspergillus sp. 1901NT-1.2.2 sponge-associated fungal strain was investigated using HPLC MS technique, and more than 23 peaks in chromatogram were detected. Only two minor identified as endocrocin terpene derivative data from GNPS database. main compound isolated known anthraquinone vismione E. absolute stereochemistry E established for first time ECD quantum chemical methods. Vismione showed high cytotoxic activity against human breast cancer MCF-7 cells, with...
Edible coatings were prepared using a mixture of 1.0 % (w/v) sodium carboxymethyl cellulose (CMC), 0.5 nanofibers (CNF), and varying concentrations mandarin oil (MO) at 0.05, 0.1, 0.2, 0.3, or 0.4 (w/v). The research investigated the physicochemical characteristics antifungal activities films on Botrytis cinerea (B. cinerea). CMC/CNF/MO used to preserve strawberries (Amaou). changes in quality activity assessed during storage 5 °C 85 ± relative humidity (RH). Results showed major components...