A5055406309- Child Nutrition and Water Access
- Trace Elements in Health
- Nutrition and Health in Aging
- Iron Metabolism and Disorders
- Nutritional Studies and Diet
- Child Nutrition and Feeding Issues
- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Lipoproteins and Cardiovascular Health
- Folate and B Vitamins Research
- Cardiac, Anesthesia and Surgical Outcomes
- Sodium Intake and Health
- Breastfeeding Practices and Influences
- Clinical Nutrition and Gastroenterology
- Hemoglobinopathies and Related Disorders
- Pregnancy and preeclampsia studies
- T-cell and B-cell Immunology
- Diet, Metabolism, and Disease
- Dietetics, Nutrition, and Education
- Consumer Attitudes and Food Labeling
- Ethics in Clinical Research
- Counseling, Therapy, and Family Dynamics
- Nuclear Physics and Applications
- HIV Research and Treatment
- Global Health and Epidemiology
University of Colorado Denver
2017-2025
University of Colorado Anschutz Medical Campus
2021-2025
Academy of Nutrition and Dietetics
2019-2024
Research International (United States)
2024
North Carolina State University
2011-2021
Eastern Michigan University
2020
Health and Human Development (2HD) Research Network
2019
RELX Group (United States)
2019
Benedictine University
2015
Children's Medical Center
1996-2008
Platelet-rich plasma (PRP) preparations are being used with moderate success to treat osteoarthritis (OA) in humans and veterinary species. Such hindered, however, by autologous nature subject tremendous patient processing variability. For this reason, there has been increasing interest the use of lysate instead traditional PRP. Platelet acellular, thereby reducing concerns over immunogenicity, contain high concentrations growth factors cytokines. In addition, platelet can be stored frozen...
The lack of a widely accepted, broadly validated tool for diagnosing malnutrition in hospitalized patients limits the ability to assess integral role nutrition as an input and outcome health, disease, treatment. This study aimed evaluate predictive validity Academy Nutrition Dietetics/American Society Parenteral Enteral (ASPEN) indicators diagnose (AAIM) determine if it can be simplified. A prospective cohort was conducted from August 2019 September 2022 with 32 hospitals United States. At...
ABSTRACT In Bangladesh, anaemia is estimated to affect 52% of children 6–59 months, with the youngest (6–23 months) experiencing highest levels (71%). Micronutrient powders (MNPs) are designed increase micronutrient intake in young children; however, some settings, prevalence may remain elevated despite high coverage MNPs. a secondary analysis Zinc Powders trial (ZiPT), we identified risk factors that were associated among Bangladeshi 9–11 months age who received standard 15‐component MNPs,...
To evaluate whether amyloid-related imaging abnormalities with edema/effusion (ARIA-E) observed in bapineuzumab clinical trials was associated specific biomarker patterns.Bapineuzumab, an anti-β-amyloid monoclonal antibody, evaluated patients mild to moderate Alzheimer disease. Amyloid PET imaging, CSF biomarkers, or volumetric MRI (vMRI) were assessed.A total of 1,512 participants underwent one more assessments; 154 developed incident ARIA-E. No differences at baseline between ARIA-E and...
Abstract Background Nutrition‐Focused Physical Exam (NFPE) feasibility is not well‐studied. We describe registered dietitian nutritionist (RDN)–reported NFPE completion for hospitalized adult and pediatric patients overall by assessment parameters. Methods Trained RDNs systematically conducted NFPEs during the Academy of Nutrition Dietetics American Society Parenteral Enteral Indicators to diagnose Malnutrition multisite cohort study ( ClinicalTrials.gov : NCT03928548). reported their...
Early diagnosis of tuberculosis (TB) and involvement the public-private partnership are critical to eradicate TB. Patients need receive proper treatment through National Tuberculosis Control Programme (NTP). This study describes various predictors for health seeking behaviour TB patients system delay made by different care providers.A cross-sectional was conducted in a public facility rural area Bangladesh. Newly diagnosed smear positive pulmonary (PTB) who were ≥ 15 years age sequentially...
Diet is among the most influential lifestyle factors impacting chronic disease risk. Nutrimetabolomics, application of metabolomics to nutrition research, allows for detection food-specific compounds (FSCs) that can be used connect dietary patterns, such as a Mediterranean-style (MED) diet, health. This validation study based upon analyses from controlled feeding MED intervention, where our team identified FSCs eight foods detected in biospecimens after consumption and may therefore serve...
Environmental enteric dysfunction (EED), a chronic inflammatory disorder of the small bowel, is suspected to impair absorption micronutrients, including zinc. The objective this study was compare zinc from micronutrient powder (MNP) over range doses in young children screened for EED with use lactulose:mannitol ratio (L:M). Bangladeshi aged 18–24 mo, grouped according high and low L:M (≥0.09 <0.09, respectively), were randomly assigned MNP 0, 5, 10, or 15 mg Zn/sachet (10 subjects per dose...
Allogeneic mesenchymal stem cells (MSCs) are a promising cell therapy for treating numerous diseases, but major histocompatibility complex (MHC)-mismatched MSCs can be rejected by the recipient’s immune system. Pre-treating with transforming growth factor-β2 (TGF-β2) to downregulate surface expression of MHC molecules may enhance ability allogeneic evade responses. We used lymphocyte proliferation assays and ELISAs analyze immunomodulatory potential TGF-β2-treated equine bone marrow-derived...
Dietary intake and biomarkers of micronutrient status 100 non-pregnant women reproductive age (NPWRA) were assessed to determine optimal levels iron, zinc, vitamin B12, folic acid include in multiply-fortified salt (MFS) that will be evaluated an upcoming trial. Weighed food records obtained from participants measure micronutrients discretionary salt, assess adequacy using Indian Nutrient Reference Values (NRVs). Statistical modeling was used fortification reduce inadequate while limiting...
ABSTRACT From 2018 to 2020, U.S. federal mandates began requiring the use of a single institutional review board (sIRB) record for federally funded, multisite studies. With an interest in efficiency site activation, we compared frequency with which local and approval three different reliance options (ways establish agreement between sIRB relying institution) were used during this period multisite, non‐federally funded study ( ClinicalTrials.gov identifier: NCT03928548). Using general linear...
Experiments on euthyroid subjects demonstrate that the renal clearance rate for radioiodide decreases at night by a factor of about 1.4 compared with daytime value, whereas thyroidal remains approximately constant. This factor, and losses iodide in sweat, feces uncollected urine must be taken into account when results short-term radioiodine studies are used to estimate accumulation stable 127iodide.
Feline immunodeficiency virus (FIV) infection in cats follows a disease course similar to HIV-1, including short acute phase characterized by high viremia, and prolonged asymptomatic low viremia generalized immune dysfunction. CD4+CD25hiFoxP3+ immunosuppressive regulatory T (Treg) cells have been implicated as possible cause of dysfunction during FIV HIV-1 infection, they are capable modulating virus-specific inflammatory responses. Additionally, the capacity feline Treg has shown be...
Abstract Background Multiple micronutrient (MN) deficiencies remain highly prevalent among women of reproductive age (WRA) and preschool-aged children (PSC) in many areas within India. Salt is an attractive vehicle for MN fortification this context, as it universally consumed fairly consistent amounts coverage iodized salt (IS) 94%. The overall objective trial to evaluate the nutritional impact quintuply-fortified with iron form encapsulated ferrous fumarate, zinc, vitamin B12, folic acid,...
A sensitive and reliable biomarker of zinc status has yet to be identified, but observational research suggests that the exchangeable pool (EZP) size may a possible biomarker. This randomized, placebo-controlled trial aimed compare change in EZP from baseline endline 174 children who were preventatively supplemented with 10 mg as part multiple micronutrient power (MNP) or standalone dispersible tablet for 24 weeks versus placebo powder. The effects systemic inflammation on also evaluated....
Environmental enteric dysfunction (EED) impairs zinc absorption from food, and deficiency may contribute to the poor growth associated with EED. We examined a standardized aqueous dose, habitual daily endogenous fecal excretion (EFZ) compared these outcomes between children grouped by lactulose mannitol ratio (L:M).
Abstract This research describes the proportion of children in four low‐ and middle‐income countries with adequate dietary practices at 6, 12, 18 24 months age how these changed over time using World Health Organisation UNICEF's infant young child feeding (IYCF) indicators. The associations between IYCF indicators anthropometric z‐scores from 6 to months, family care (FCIs) are described. was a longitudinal study offspring participants Women First Preconception Maternal Nutrition Trial...