Jasmine Young
A5006418591- Enzyme Structure and Function
- Protein Structure and Dynamics
- Advanced Proteomics Techniques and Applications
- Genetics, Bioinformatics, and Biomedical Research
- Scientific Computing and Data Management
- Bioinformatics and Genomic Networks
- Genomics and Phylogenetic Studies
- Advanced Electron Microscopy Techniques and Applications
- Computational Drug Discovery Methods
- Electron and X-Ray Spectroscopy Techniques
- RNA and protein synthesis mechanisms
- Risk and Safety Analysis
- Microbial Metabolic Engineering and Bioproduction
- Machine Learning in Materials Science
- Gene expression and cancer classification
- Distributed and Parallel Computing Systems
- Research Data Management Practices
- Mass Spectrometry Techniques and Applications
- Glycosylation and Glycoproteins Research
- Advanced Data Storage Technologies
- Advanced NMR Techniques and Applications
- Chemical Safety and Risk Management
- Graphite, nuclear technology, radiation studies
- Biomedical Text Mining and Ontologies
- Crystallization and Solubility Studies
Rutgers, The State University of New Jersey
2014-2024
Worldwide Protein Data Bank
2009-2024
Rutgers Sexual and Reproductive Health and Rights
2020-2021
North Carolina Central University
2015
Wellcome Trust
2014
European Bioinformatics Institute
2012-2014
University of California, San Diego
2010-2013
University of Montana
2013
San Diego Supercomputer Center
2007-2012
Scripps Research Institute
2010-2012
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), the US data center global PDB archive and a founding member of Worldwide partnership, serves tens thousands depositors in Americas Oceania makes 3D macromolecular structure available at no charge without restrictions to millions RCSB.org users around world, including >660 000 educators, students members curious public using PDB101.RCSB.org. include structural biologists crystallography,...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, rcsb.org), the US data center global PDB archive, serves thousands of Depositors in Americas and Oceania makes 3D macromolecular structure available at no charge without usage restrictions to more than 1 million rcsb.org Users worldwide 600 000 pdb101.rcsb.org education-focused around globe. include structural biologists using crystallography, nuclear magnetic resonance spectroscopy electron microscopy....
The Protein Data Bank (PDB) is the single global archive of experimentally determined three-dimensional (3D) structure data biological macromolecules. Since 2003, PDB has been managed by Worldwide (wwPDB; wwpdb.org), an international consortium that collaboratively oversees deposition, validation, biocuration, and open access dissemination 3D macromolecular data. Core Archive houses atomic coordinates more than 144 000 structural models proteins, DNA/RNA, their complexes with metals small...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, http://rcsb.org), the US data center global PDB archive, makes freely available to all users, from structural biologists computational and beyond. New tools resources have been added RCSB web portal in support of a 'Structural View Biology.' Recent developments improved User experience, including high-speed NGL Viewer that provides 3D molecular visualization any browser, file download enhanced organization...
The RCSB Protein Data Bank (RCSB PDB) web site ( http://www.pdb.org ) has been redesigned to increase usability and cater a larger more diverse user base. This article describes key enhancements new features that fall into the following categories: (i) query analysis tools for chemical structure searching, refinement, tabulation export of results; (ii) customization alerts; (iii) pair-wise representative protein alignments; (iv) visualization large assemblies; (v) integration structural data...
This Meeting Review describes the proceedings and conclusions from inaugural meeting of Electron Microscopy Validation Task Force organized by Unified Data Resource for 3DEM (http://www.emdatabank.org) held at Rutgers University in New Brunswick, NJ on September 28 29, 2010. At workshop, a group scientists involved collecting electron microscopy data, using data to determine three-dimensional (3DEM) density maps, building molecular models into maps explored how assess models, other that are...
The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one the leading resources in biology biomedicine worldwide. Our efforts over past 2 years focused on enabling a deeper understanding structural providing new views that support both basic applied research education. Herein, we describe recently introduced data annotations including integration with external resources, such as gene drug databases, visualization tools...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) develops tools and resources that provide a structural view of biology research education. RCSB PDB web site (http://www.rcsb.org) uses the curated 3D macromolecular data contained in archive to offer unique methods access, report visualize data. Recent activities have focused on improving simple complex searches data, creating specialized access chemical component providing domain-based alignments. New...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), founding member of the Worldwide (wwPDB), is US data center open-access PDB archive. As wwPDB-designated Archive Keeper, RCSB also responsible security. Annually, serves >10 000 depositors three-dimensional (3D) biostructures working on all permanently inhabited continents. delivers from its research-focused RCSB.org web portal to many millions consumers based in virtually every United Nations-recognized...
Abstract Analyses of publicly available structural data reveal interesting insights into the impact three‐dimensional (3D) structures protein targets important for discovery new drugs (e.g., G‐protein‐coupled receptors, voltage‐gated ion channels, ligand‐gated transporters, and E3 ubiquitin ligases). The Protein Data Bank (PDB) archive currently holds > 155,000 atomic‐level 3D biomolecules experimentally determined using crystallography, nuclear magnetic resonance spectroscopy, electron...
The Worldwide PDB recently launched a deposition, biocuration, and validation tool: OneDep. At various stages of OneDep data processing, reports for three-dimensional structures biological macromolecules are produced. These based on recommendations expert task forces representing crystallography, nuclear magnetic resonance, cryoelectron microscopy communities. provide useful metrics with which depositors can evaluate the quality experimental data, structural model, fit between them. module...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), funded by the US National Science Foundation, Institutes of Health, and Department Energy, has served structural biologists (PDB) data consumers worldwide since 1999. RCSB PDB, a founding member Worldwide (wwPDB) partnership, is center global PDB archive housing biomolecular structure data. also responsible security data, as wwPDB-designated Archive Keeper. Annually, serves tens thousands three-dimensional...
Abstract Summary: The Chemical Component Dictionary (CCD) is a chemical reference data resource that describes all residue and small molecule components found in Protein Data Bank (PDB) entries. CCD contains detailed descriptions for standard modified amino acids/nucleotides, ligands solvent molecules. Each definition includes of properties such as stereochemical assignments, descriptors, systematic names idealized coordinates. content, preparation, validation distribution this dataset are...
In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for deposition and validation of cryoEM structures, with focus on single-particle analysis. The meeting attended by 45 experts in processing, model building refinement, validation, archiving such structures. This report describes the workshop's motivation history, topics discussed, consensus recommendations resulting from workshop. Some challenges future methods-development efforts this area are also...
The Worldwide Protein Data Bank (wwPDB; wwpdb.org) is the international collaboration that manages deposition, processing and distribution of PDB archive. online archive at ftp://ftp.wwpdb.org repository for coordinates related information more than 47 000 structures, including proteins, nucleic acids large macromolecular complexes have been determined using X-ray crystallography, NMR electron microscopy techniques. members wwPDB–RCSB (USA), MSD-EBI (Europe), PDBj (Japan) BMRB (USA)–have...
Abstract The existence of a large number proteins for which both nuclear magnetic resonance (NMR) and X‐ray crystallographic coordinates have been deposited into the Protein Data Bank (PDB) makes statistical comparison corresponding crystal NMR structural models over data set possible, facilitates study effect environment other factors on structure. We present an approach detecting statistically significant differences between is based superposition analysis distributions atomic positions...
This letter announces that PDBx/mmCIF format files will become mandatory for crystallographic depositions to the Protein Data Bank (PDB).