A5071896859- Enzyme Structure and Function
- Protein Structure and Dynamics
- RNA and protein synthesis mechanisms
- DNA and Nucleic Acid Chemistry
- Genetics, Bioinformatics, and Biomedical Research
- Bioinformatics and Genomic Networks
- Advanced Proteomics Techniques and Applications
- Biomedical Text Mining and Ontologies
- Advanced Electron Microscopy Techniques and Applications
- Genomics and Phylogenetic Studies
- Bacterial Genetics and Biotechnology
- Bacteriophages and microbial interactions
- Advanced biosensing and bioanalysis techniques
- RNA modifications and cancer
- Scientific Computing and Data Management
- Collagen: Extraction and Characterization
- Chemical Synthesis and Analysis
- Metal complexes synthesis and properties
- Biochemical and Molecular Research
- Microbial Metabolic Engineering and Bioproduction
- Computational Drug Discovery Methods
- Metabolomics and Mass Spectrometry Studies
- Electron and X-Ray Spectroscopy Techniques
- Crystallography and molecular interactions
- Synthesis and Characterization of Heterocyclic Compounds
Rutgers, The State University of New Jersey
2016-2025
University of Southern California
2015-2025
Deutsches Elektronen-Synchrotron DESY
2024
The University of Texas at Dallas
2024
Southern Utah University
2024
University of Connecticut
2024
Convergent Science (United States)
2021-2022
Rutgers Sexual and Reproductive Health and Rights
2012-2020
Worldwide Protein Data Bank
2014-2020
Stanford University
2020
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data biological macromolecules. This paper describes goals PDB, systems in place for deposition and access, how to obtain further information, near-term plans future development resource.
The Protein Data Bank [PDB; Berman, Westbrook et al. (2000), Nucleic Acids Res. 28 , 235–242; http://www.pdb.org/] is the single worldwide archive of primary structural data biological macromolecules. Many secondary sources information are derived from PDB data. It starting point for studies in bioinformatics. This article describes goals PDB, systems place deposition and access, how to obtain further plans future development resource. reader should come away with an understanding scope what...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, rcsb.org), the US data center global PDB archive, serves thousands of Depositors in Americas and Oceania makes 3D macromolecular structure available at no charge without usage restrictions to more than 1 million rcsb.org Users worldwide 600 000 pdb101.rcsb.org education-focused around globe. include structural biologists using crystallography, nuclear magnetic resonance spectroscopy electron microscopy....
The worldwide Protein Data Bank (wwPDB) is the international collaboration that manages deposition, processing and distribution of PDB archive. online archive a repository for coordinates related information more than 38 000 structures, including proteins, nucleic acids large macromolecular complexes have been determined using X-ray crystallography, NMR electron microscopy techniques. founding members wwPDB are RCSB (USA), MSD-EBI (Europe) PDBj (Japan) [H.M. Berman, K. Henrick H. Nakamura...
The structure of a protein triple helix has been determined at 1.9 angstrom resolution by x-ray crystallographic studies collagen-like peptide containing single substitution the consensus sequence. This adopts triple-helical that confirms basic features from fiber diffraction on collagen: supercoiling polyproline II helices and interchain hydrogen bonding follows model Rich Crick. In addition, provides new information concerning nature this fold. Each is surrounded cylinder hydration, with...
The Protein Data Bank (PDB) is the single global archive of experimentally determined three-dimensional (3D) structure data biological macromolecules. Since 2003, PDB has been managed by Worldwide (wwPDB; wwpdb.org), an international consortium that collaboratively oversees deposition, validation, biocuration, and open access dissemination 3D macromolecular data. Core Archive houses atomic coordinates more than 144 000 structural models proteins, DNA/RNA, their complexes with metals small...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, http://rcsb.org), the US data center global PDB archive, makes freely available to all users, from structural biologists computational and beyond. New tools resources have been added RCSB web portal in support of a 'Structural View Biology.' Recent developments improved User experience, including high-speed NGL Viewer that provides 3D molecular visualization any browser, file download enhanced organization...
The RCSB Protein Data Bank (RCSB PDB) web site ( http://www.pdb.org ) has been redesigned to increase usability and cater a larger more diverse user base. This article describes key enhancements new features that fall into the following categories: (i) query analysis tools for chemical structure searching, refinement, tabulation export of results; (ii) customization alerts; (iii) pair-wise representative protein alignments; (iv) visualization large assemblies; (v) integration structural data...
This Meeting Review describes the proceedings and conclusions from inaugural meeting of Electron Microscopy Validation Task Force organized by Unified Data Resource for 3DEM (http://www.emdatabank.org) held at Rutgers University in New Brunswick, NJ on September 28 29, 2010. At workshop, a group scientists involved collecting electron microscopy data, using data to determine three-dimensional (3DEM) density maps, building molecular models into maps explored how assess models, other that are...
The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one the leading resources in biology biomedicine worldwide. Our efforts over past 2 years focused on enabling a deeper understanding structural providing new views that support both basic applied research education. Herein, we describe recently introduced data annotations including integration with external resources, such as gene drug databases, visualization tools...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) develops tools and resources that provide a structural view of biology research education. RCSB PDB web site (http://www.rcsb.org) uses the curated 3D macromolecular data contained in archive to offer unique methods access, report visualize data. Recent activities have focused on improving simple complex searches data, creating specialized access chemical component providing domain-based alignments. New...
The Protein Data Bank began as a grassroots effort in 1971. It has grown from small archive containing dozen structures to major international resource for structural biology more than 40000 entries. interplay of science, technology and attitudes about data sharing have all played role the growth this resource.
Three-dimensional Electron Microscopy (3DEM) has become a key experimental method in structural biology for broad spectrum of biological specimens from molecules to cells. The EMDataBank project provides unified portal deposition, retrieval and analysis 3DEM density maps, atomic models associated metadata (emdatabank.org). We provide here an overview the rapidly growing data archives, which include maps EM Data Bank map-derived Protein Bank. In addition, we describe progress approaches...
Cryo-electron microscopy reconstruction methods are uniquely able to reveal structures of many important macromolecules and macromolecular complexes. EMDataBank.org, a joint effort the Protein Data Bank in Europe (PDBe), Research Collaboratory for Structural Bioinformatics (RCSB) National Center Macromolecular Imaging (NCMI), is global 'one-stop shop' resource deposition retrieval cryoEM maps, models associated metadata. The unifies public access two major archives containing EM-based...
The Worldwide PDB recently launched a deposition, biocuration, and validation tool: OneDep. At various stages of OneDep data processing, reports for three-dimensional structures biological macromolecules are produced. These based on recommendations expert task forces representing crystallography, nuclear magnetic resonance, cryoelectron microscopy communities. provide useful metrics with which depositors can evaluate the quality experimental data, structural model, fit between them. module...