A5100350956- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Shoulder Injury and Treatment
- Neuroscience of respiration and sleep
- Sports injuries and prevention
- Neuroendocrine regulation and behavior
- Infant Health and Development
- Shoulder and Clavicle Injuries
- Tendon Structure and Treatment
- Osteoarthritis Treatment and Mechanisms
- Orthopedic Surgery and Rehabilitation
- Orthopaedic implants and arthroplasty
- Respiratory and Cough-Related Research
- Surgical site infection prevention
- Vascular Procedures and Complications
- Cardiovascular Issues in Pregnancy
- Electrospun Nanofibers in Biomedical Applications
- Pituitary Gland Disorders and Treatments
- Sexual function and dysfunction studies
- Hip and Femur Fractures
- Axon Guidance and Neuronal Signaling
- Pulmonary Hypertension Research and Treatments
- Brain Metastases and Treatment
- Meningioma and schwannoma management
- Lower Extremity Biomechanics and Pathologies
Sichuan University
2018-2025
West China Hospital of Sichuan University
2018-2025
Chengdu Third People's Hospital
2024-2025
Chongqing Medical University
2025
Southwest Jiaotong University
2025
Chengdu Second People's Hospital
2022
Harbin Medical University
2009-2022
Qiqihar Medical University
2021
Shanxi Medical University
2019
Beijing Tian Tan Hospital
2015
Abstract Osteoarthritis (OA) is a degenerative joint disease accompanied with the loss of cartilage and consequent nociceptive symptoms. Normal articular maintains at aneural state. Neuron guidance factor Semaphorin 3A (Sema3A) membrane-associated secreted protein chemorepulsive properties for axons. However, role Sema3A in still not clear. In present studies, we investigated functions OA development mice, non-human primates, patients OA. has protective effect on degradation, validated by...
The rostral fastigial nucleus (FNr) of the cerebellum facilitates respiratory response to hypercapnia. We hypothesized that some FNr sites are chemosensitive focal tissue acidosis and contribute, at least partially, modulation. Minute ventilation (V˙e) was recorded in 21 anesthetized spontaneously breathing rats. Acetazolamide (AZ; 50 μM) microinjected unilaterally into while an isocapnic condition maintained throughout experiment. AZ (1 or 20 nl) injection significantly elevated V˙e (46.0 ±...
Xu, Fadi, Donald T. Frazier, Zhong Zhang, David M. Baekey, and Roger Shannon. Cerebellar modulation of cough motor pattern in cats. J. Appl. Physiol. 83(2): 391–397, 1997.—The cerebellum modulates respiratory muscle activity part via its influence on the central generator. Because coughing requires well-coordinated activity, studies were conducted to determine whether influences centrally generated pattern. Integrated phrenic lumbar efferent neurograms ([Formula: see text]PN [Formula:...
There is still a lack of clinical data in arthroscopic treatment for treating multiple ligament injuries. This study aims to evaluate the outcomes patients with injuries undergoing based on classification stage and type injury.A prospective, trial was planned, which included 95 (58 men 37 women; age: 42.8 ± 11.9 [range, 18-63] years) from October 2017 June 2018. Injuries were classified into three stages (emergency < 24 h; acute stage: h 3 weeks, chronic > weeks) six types (KD I-VI) time...
Tissue engineering is a promising treatment strategy for meniscal regeneration after injury. However, existing scaffold materials and seed cells still have many disadvantages. The objective of the present study to explore feasibility peripheral blood-derived mesenchymal stem (PBMSCs) augmented with demineralized cortical bone matrix (DCBM) pretreated TGF-β3 as tissue-engineered meniscus graft repair effect. PBMSCs were collected from rabbit blood subjected three-lineage differentiation flow...
The killer turn has been documented as the primary drawback of posterior cruciate ligament (PCL) reconstruction. Fanelli advocated placing tibial tunnel outlet in inferior lateral part PCL fovea to reduce turn. This study aimed confirm validity Fanelli's viewpoint regarding reconstruction technique and assess specific area on fovea.The geometrical data model were obtained by nuclear magnetic resonance (MRI) computerized tomography (CT), with images taken from a healthy Chinese volunteer....
We have reported that the phrenic neurogram (PN) is modulated by stimulation of fastigial nucleus (FN) cerebellum. The present study was undertaken to search for brainstem site(s) involved in FN efferent pathway modulate nerve activities. Experiments were performed on 35 anesthetized, paralyzed, and ventilated cats, using PN as index respiratory motor output. Results showed bilateral electrolytic lesions red (RN), paramedian reticular (PRN), or pontine group (PRG) had little effect ability...
Our previous three-dimensional finite element analysis found that posterior cruciate ligament (PCL) reconstruction in the modified tibial tunneling placement (MTT, 10 mm inferior and 5 lateral to PCL anatomical insertion) could reduce peak stress of graft may killer turn. The purpose current study was compare biomechanical results between MTT traditional technique (TTT, during transtibial reconstruction.Fifty-six 3D-printed tibia models fresh mature porcine flexor digitorum tendons were...
Abstract The biomechanical characteristics of tendon grafts is essential for reconstructive surgery due to its great role in providing a good mechanical environment healing and regeneration. In our previous studies, the decellularized slices (DTSs) bovine sheets (DBTSs) scaffolds were successfully developed. However, influence integrity tendinous membrane (endotenon epitenon) fascicle on these two was not investigated. this study, we assessed derived effect characteristics. results...
Craniopharyngiomas are rare, benign, epithelial neoplasms that account for about 5% of all intracranial neoplasms. mainly confined to the intrasellar and suprasellar regions, with location being most common. Exclusively infrasellar craniopharyngiomas no sellar involvement extremely rare.[12] We reported an craniopharyngioma involving sphenoid sinus clivus in a 16-year-old girl, discussed clinical features management this tumor. A girl presented 6-month history progressive headaches nasal...
To investigate the relationship between different dietary patterns and levels of bone mineral density (BMD) in middle-aged aged people, to provide references for nutritional prevention osteoporosis.A total 476 residents 45 yr or more Qiqihar City were enrolled from Aug 2018 Feb 2019. They took a Food Frequency Questionnaire survey. Their analyzed using factor analysis method, BMD detected ultrasound densitometer, explore levels.Four obtained survey: relatively balanced, oil-salt, milk-tuber,...
Objective To investigate the clinical effects of individualized repair and reconstruction surgery for multiple ligament injury dislocation knee joint based on stage classification diagnosis. Methods From January 2018 to 2019, 42 patients with were treated. There 27 males 15 females, aged from 30 63 (47.35±11.90) years old, including 17 left knees, 23 right knees 2 bilateral knees. All injuries dislocations classified by stages improved Schenck Among them, cases in acute (≤3 weeks), 19 old...
This study examines the differential association between sex and depression, possible mediating pathways.We analysed survey data from 296 (age 7-17.1 years) cancer survivors three centres affiliated with Beijing Children's Hospital. Linear regression analysis was used to assess depression. Quantile estimate coefficients (β) 95% confidence intervals for in depression at different quantiles. Mediation multiple mediators explore effects of on depression.Using linear regression, we found that...
We have reported that the phrenic neurogram (PN) is modulated by stimulation of fastigial nucleus (FN) cerebellum. The present study was undertaken to search for brainstem site(s) involved in FN efferent pathway modulate nerve activities. Experiments were performed on 35 anesthetized, paralyzed, and ventilated cats, using PN as index respiratory motor output. Results showed bilateral electrolytic lesions red (RN), paramedian reticular (PRN), or pontine group (PRG) had little effect ability...
Objective Observe the low-energy extracorporeal shock wave (LESW) on rabbit penile tissue damage and repair, to investigate security of LESW therapy erectile dysfunction (ED). Methods Common adult male rabbits(n=35) were randomly divided into 6 groups (5 experimental group, 1 control group). Same dose (E=0.09 mJ/m2, 60 shocks/min, 500 shocks each time side) treat corpus cavernosum. Animals' are observed existence corresponding damage. Corpus cavernosum made hematoxylin eosin (HE),...
Objective To observe the effect of dietary fat on diet-induced obesity in mice. Methods Forty 3-week.old male C57BL6 mice were randomly divided into four groups(1-4)fed withdiets different amounts lard [0%,20%,40%and 60%of total energy (kcal)].Plasma glucose,lipids,insulin and other parameters measured after 7 weeks.Moreover,the livers kidneys taken for histopathological evaluation white fatty tissues to analyse adipose'associated geneexpressions using gene chip technology.Results There...
Objective To evaluate the dose distribution of target volume and cranial base in nasopharyngeal carcinoma ( NPC ) treated with facial-cervical fields, to analyze differences using different isoeenters CT-simulator treatment planning system (TPS). Methods Eleven patients were by conventional radiotherapy as their primary treatment. All simulated simulator field borders marked thin lead wires on mask. Then scanned CT-sim same immobilization. The CT images transferred TPS copied DRR, then GTV...