A5100377476- Thyroid Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Vitamin D Research Studies
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Adrenal Hormones and Disorders
- Pituitary Gland Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Stress Responses and Cortisol
- Genetic Associations and Epidemiology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Kruppel-like factors research
- Folate and B Vitamins Research
- Periodontal Regeneration and Treatments
- Traditional Chinese Medicine Analysis
- Obesity and Health Practices
- Gut microbiota and health
- High Altitude and Hypoxia
- Pharmacology and Obesity Treatment
- Sexual function and dysfunction studies
- Selenium in Biological Systems
- Suicide and Self-Harm Studies
- Extracellular vesicles in disease
- Bone health and treatments
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024-2025
Chongqing Medical University
2024-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2024
Peking Union Medical College Hospital
2023-2024
Beijing University of Chinese Medicine
2024
China Medical University
2021-2024
First Affiliated Hospital of Anhui Medical University
2024
Anhui Medical University
2024
National Clinical Research Center for Digestive Diseases
2024
First Hospital of China Medical University
2021-2024
The purpose of this study was to implore the association among clinical features, long-term fertility outcomes and anatomical location adenomyosis identified by ultrasound. We collected data non-pregnant patients between 20 40 years old who had undergone surgical exploration for benign gynecological conditions at our institution January 2010 December 2017. A total 158 women met inclusion criteria were allocated into three groups according ultrasound-determined location: anterior (Group A),...
Abstract. The GHRH test and L-dopa were performed in 12 normal young men (24.1 ± 1.1 years) elderly (77.8±1.4 to investigate age-related changes secretion of GHRH, GH IGF-I. basal plasma levels not significantly different men, but the level IGF-I was higher (159.0± 11.7 vs 86.7± 11.6 μg/1). area under curve for less group (35.1 ±5.9 11.2 2.1 μg · h −1 1 , p<0.001). AUCs responses 32.0±2.7 20.3±1.8 ng (p<0.001), 21.8±4.6 5.4±1.1 (p<0.01), respectively, indicating decreased releases...
Objectives: The objective of this study was to examine the urinary iodine concentration (UIC)–thyroid autoimmunity (TAI) association and UIC–selenium intake interaction in U.S. adults. Methods: We analyzed 2007–2012 National Health Nutrition Examination Survey (NHANES) data on ≥20-year-old adults (n = 6612). Their food supplemental selenium measured. associations UIC with thyroid peroxidase antibody (TPOAb) positivity, thyroglobulin (TgAb) TAI were assessed via weighted multivariable...
Plasma growth hormone (GH) responses to various stimuli were examined in 21 patients with GH-producing pituitary adenomas, classified into three types by the immunohistochemistry of cytokeratin and glycoprotein α-subunit distribution. Seven type 1 adenomas exclusively composed cells which formed a dot-like pattern; they chromophobic hematoxylin eosin (H & E), occasionally positive for GH, almost completely negative α-subunit. Thirteen 2 that had perinuclear distribution; eosinophilic H E,...
The function of the growth hormone-releasing hormone (GHRH)-growth (GH) axis in Cushing's disease was studied by monitoring (a) GH responses to GHRH loading and L-dopa loading, (b) response (c) daytime profiles plasma concentration. release following blunted patients as compared that age-matched control subjects. However, similar controls. levels four measured every 20 min a highly sensitive immunoradiometric assay for showed pulsatile secretion at low during observation period. These...
Objective This study was a prospective assessment of the epidemiological characteristics metabolic syndrome (MetS) in cities Northeast China. We explored factors that affect occurrence and outcome MetS according to sex. Design Methods longitudinal survey assessing status among 750 urban community residents At baseline, intra-abdominal fat area measured by MRI, simple anthropometric parameters (body mass index (BMI), waist circumference (WC), etc.) were used evaluate distribution; blood...
A site‐directed anti‐peptide antibody (anti‐hGHRHRc18) was generated against the cytoplasmic tail of human GHRH receptor. The dissociation constant ( K d ) and binding site (AbT) anti‐hGHRHRc18 were 2.5 nmol/l 0.54 nmol/l, respectively. In an immunoblotting experiment, affinity‐purified specifically recognized a single 50‐kDa protein in pituitary. screening expression receptor extra‐pituitary tissues, only kidney showed 52‐kDa protein. Our results suggest that exhibits tissue‐specific...
Pericytes (PCs) are versatile cells integral to the microcirculation wall, exhibiting specific stem cell traits. They essential in modulating blood flow, ensuring vascular permeability, maintaining homeostasis, and aiding tissue repair process. Given their involvement numerous disease-related pathological physiological processes, regulation of PCs has emerged as a focal point research. Adenomyosis is characterized by presence active endometrial glands stroma encased an enlarged proliferative...
Purpose: The aim of our study was to explore the relation between serum levels non-enzymatic antioxidants, thyroid function with risk non-suicidal self-injury (NSSI) in depressed adolescents. Patients and Methods: We retrospected electronic records 454 hospitalized patients aged 13– 17 years old a diagnosis major depressive disorder (239 NSSI 215 subjects without NSSI), collected their demographic clinical information, including total bilirubin (Tbil), uric acid (UA), free triiodothyronine...
Objective Addressing the rising prevalence of pain disorders and limitations current analgesics, our study explores repurposing antihypertensive drugs for management, inspired by link between hypertension pain. We leverage a drug-target Mendelian Randomization (MR) approach to explore their dual benefits establish causal connections. Methods A comprehensive compilation drug classes was undertaken through British National Formulary, with target genes identified using DrugBank database....
Objectives: Observational research shows associations of the gut microbiota and its metabolites with autoimmune thyroid disease (AITD), but causality is undetermined. Methods: Two-sample Mendelian randomization (MR) was employed to analyze association AITD. A total 119 microbiotas nine fecal/circulating were exposures. AITD, Graves’ (GD), Hashimoto’s thyroiditis (HT) outcomes. Inverse-variance weighting (IVW) primarily used assess causality; Cochran’s Q heterogeneity. Sensitivity analyses...
Background: Platelet-rich plasma (PRP) is an integral biotherapeutic modality with evolving significance in the medical domain. Despite its expanding applications, a comprehensive bibliometric evaluation essential to understand development and impact. Methods: The Web of Science core collection subject search identified articles pertinent PRP applications. Analytical tools, including CiteSpace, VOSviewer, Bibliometrix (R-Tool for R-Studio), TBtools, SCImago Graphica, Origin, Excel,...
Mucosal healing (MH) is the major therapeutic target for Crohn's disease (CD). As most commonly involved intestinal segment, small bowel (SB) assessment crucial CD patients. Yet, it poses a significant challenge due to its limited accessibility through conventional endoscopic methods. To establish noninvasive radiomic model based on computed tomography enterography (CTE) MH in SBCD Seventy-three patients diagnosed with were included and divided into training cohort (n = 55) test 18)....
Women with hypothyroidism need to increase exogenous thyroid hormone levels during pregnancy reduce adverse outcomes. Few studies have reported the effect of gestational levothyroxine (LT4) variations on postpartum LT4 treatment.Women were classified as having subclinical (SCH) (n = 101), overt (OH) caused by autoimmune thyroiditis (AIT-OH), OH following thyroidectomy for benign disease (BA-OH) 66), and after surgery papillary cancer (PTC-OH) 46). Thyroid function was monitored, therapy...
Abstract Background : Chinese topography appears a three-rung ladder-like distribution of decreasing elevation from northwest to southeast, which is divided by two sloping edges. To explore the association between regions and thyroid disorders according unique topographic features, we conducted an epidemiological cross-sectional study 2015–2017 that covered all 31 mainland provinces. Methods A total 78,470 participants aged ≥18 years nationally representative were included. Serum peroxidase...
Background: Adenomyosis (AM) is a common benign gynaecologic disease characterized by dysmenorrhea and heavy menstrual bleeding requires for long-term management. Levonorgestrel - releasing Intrauterine System (LNG-IUS) long-acting hormone-releasing uterine device which has benefits in relieving pain reducing bleeding. Objectives: To summarise the current available evidence regarding LNG-IUS treatment of AM to identify potential research gaps. Search Strategy: We performed systematic search...
Objective: To investigate the changes of ankle-brachial index (ABI) and peak velocity dorsal foot artery in patients with type 2 diabetes mellitus lower extremity vascular disease treated Yingweifang. Methods: 36 cases were observed, including 13 Yin deficiency hot, 9 qi 14 Yang deficiency. Oral "Yingwei Fang" capsule, 5 capsules per time, 3 times a day, combined dialectical TCM theory treatment, conventional treatment such as hypoglycemia. Changes flow rate measured after 150 days compared...