Background: Strain gauge analysis and finite element (FE) simulations were used to estimate the bone strain micromovement at bone–implant interface (BII) for platform switching different diameters of a single, immediately loaded mandibular implant. Methods: Four models created, including 5‐mm‐diameter implants assembled with abutments that 5 or 4 mm in diameter on bonded (delay‐loading treatment) contact (immediate‐loading BIIs; model an implant 3.75 was also analyzed. Vertical lateral loads...

Using a membrane filter assay, we have obtained results from both kinetic and competition experiments indicating that histones bind more strongly to bromodeoxyuridine-substituted DNA than normal DNA. At 37° C in our standard buffer of 0.2 M ionic strength, the rate dissociation HI, H2, H4 BrdU-substituted is respectively 7, 4, 2 times slower it Competition show an even greater difference between with respect histone binding. The tighter binding interest because known effects BrdU on...

Hinokitiol displays potent antimicrobial activity. It has been used in toothpaste and oral-care gel to improve the oral lichen planus reduce halitosis. The aim of this study was evaluate activity 3 different dental root canal sealers with hinokitiol (sealers+H) their physical biological effects. AH Plus (epoxy amine resin-based, AH), Apexit (calcium-hydroxide-based, AP), Canals (zinc-oxide-eugenol-based, CA), were study. original CA exhibited strong anti-methicillin-resistant Staphylococcus...

Abstract Functionally graded material (FGM) had been developed as a potential implant to replace titanium for its improved capability of initial osseointegration. The idea behind FGM dental is that properties can be tailored in accordance with the biomechanical needs at different regions adapting hosting bony tissues, therefore creating an overall integration and stability entire restoration. However, there have very few reports available so far on predicting bone remodeling induced by...

The aim of this study was to evaluate the effects cortical bone thickness and trabecular elastic modulus on strain in surrounding an immediately loaded implant. We also examined correlations between structure following indices primary implant stability: insertion torque value (ITV), Periotest (PTV), stability quotient (ISQ).The ITV, PTV, ISQ were measured 24 artificial jaw models representing with four thicknesses (0, 1, 2, 3 mm) moduli (137, 47.5, 23, 12.4 MPa). Two loading conditions...

Chemical manipulations of the implant surface produce a bactericidal feature to prevent infections around dental implants. Despite successful use bismuth against mucosal and dermis infections, antibacterial effect in oral cavity remains under investigation. The aim this study was evaluate activities compounds Actinobacillus actinomycetemcomitans, Staphylococcus mutans, methicillin-resistant aureus (MRSA), investigate antimicrobial effects doped micro-arc oxidation (MAO) titanium via an agar...

The purpose of this research is to compare the cytotoxicity polyetheretherketone (PEEK) and polyetherketoneketone (PEKK) with conventional dental implant–abutment materials, namely titanium alloy (Ti-6Al-4V) yttria-stabilized tetragonal zirconia polycrystal (Y-TZP), evaluate cell metabolic activity, cytotoxicity, inflammation potential human oral fibroblasts (HOF) on these materials. Disk-shaped specimens were designed prepared via a computer-aided manufacturing technology system. Surface...

Poly-ether-ether-ketone (PEEK) is an aesthetically pleasing natural material with good biocompatibility and shock absorption characteristics. The application of PEEK as a dental implant or abutment expected to reduce the risk failure enhance aesthetics. Given that approximately one in 15 patients have allergic reactions antibiotics, photodynamic therapy (PDT) has been gaining attention alternative treatment. Herein, applicability implants abutments was investigated using analyses, biofilm...

Periodontitis, a chronic inflammatory disease caused by microbial communities carrying pathogens, leads to the loss of tooth-supporting tissues and is significant contributor tooth loss. This study aims develop novel injectable cell-laden hydrogel consisted collagen (COL), riboflavin, dental light-emitting diode (LED) photo-cross-linking process for periodontal regeneration. Utilizing α-SMA ALP immunofluorescence markers, we confirmed differentiation human ligament fibroblasts (HPLFs) into...

A comparison study is reported on the ultrasonic assessment of human trabecular and bovine bone samples. Both velocity attenuation were evaluated through a transmission insertion technique correlated with mineral density as determined single photon absorptiometry. For 1-MHz transducer pair cancellous samples correlations 0.91 0.89 between attenuation, respectively. 500-kHz 0.81 samples, 0.90 -0.31 for respectively, 1 MHz pair. transducers, 0.85 -0.17 By combining both in multivariate...

Abstract Background Lysyl oxidase (LOX) is a copper‐dependent enzyme that cross‐links collagen and elastin in the extracellular matrix. LOX overexpressed various tumors. The manner which affects tumor growth remains controversial. Methods Chemical treatment gene transfection were used to induce overexpression or inhibition cell lines SAS SVEC4‐10. mRNA , protein, activity confirmed before tube formation assay tumorigenesis. microvessels section detected by immunostaining CD31‐positive...

Mitochondrial DNA synthesis requires the supply of thymidine triphosphate (dTTP) independent nuclear replication. In resting and differentiating cells that withdraw from cell cycle, mitochondrial kinase 2 (TK2) mediates monophosphate (dTMP) formation for dTTP biosynthesis in mitochondria. However, a (TMPK) phosphorylates dTMP to form diphosphate (dTDP) mitochondria remains undefined. Here, we identified an expressed sequence tag cDNA, which encodes TMPK with import at its N‐terminus...

Given their wide range of biomedical applications, hydroxyapatite (HA) nanoparticles are an attractive material widely used in many fields. Therefore, a simple, inexpensive, and stable process for the synthesis HA is necessary to meet current needs. Herein, we studied assisted by four surfactants, namely cation, anion, non-ionic, zwitterion templates, verify phase, aspect ratio, morphology, biocompatibility under different environments (i.e., pH 4 9) before after calcination. Results showed...