A5001082950- Ocular Surface and Contact Lens
- Systemic Sclerosis and Related Diseases
- Nasolacrimal Duct Obstruction Treatments
- Corneal surgery and disorders
- Antifungal resistance and susceptibility
- Dermatologic Treatments and Research
- Systemic Lupus Erythematosus Research
- Corneal Surgery and Treatments
- Receptor Mechanisms and Signaling
- Ocular Oncology and Treatments
- Cancer and Skin Lesions
- Spondyloarthritis Studies and Treatments
- Fungal Infections and Studies
- Rheumatoid Arthritis Research and Therapies
- Urticaria and Related Conditions
- Glaucoma and retinal disorders
- Nonmelanoma Skin Cancer Studies
- Autoimmune Bullous Skin Diseases
- Skin Diseases and Diabetes
- Allergic Rhinitis and Sensitization
- Pharmacological Effects and Assays
- Nematode management and characterization studies
- Retinal Diseases and Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Analytical Chemistry and Chromatography
University of Debrecen
2011-2021
University of Oslo
2010
The aim of the present study is to determine corneal physiology and endothelial morphology after proper image analysis technique in type I II diabetic patients. HbA1c level grade retinopathy were also recorded correlated with parameters.41 eyes 21 patients 59 30 diabetes mellitus (mean age was 40.97 ± 15.46 64.36 10.47 years) examined compared age-matched controls. Endothelial cell density (ECD), mean area, coefficient variation central thickness, intraocular pressure, recorded.There a...
Objectives: Systemic sclerosis (SSc) is a rare, chronic connective tissue disease involving multiple organ systems, including the eye. We evaluated detailed clinical ocular manifestations of outpatients with SSc.Methods: Demographics, duration and subtype, nailfold capillaroscopy (NFC) patterns laboratory parameters encompassing autoantibody profile 51 SSc patients were evaluated, general examination was performed for each participant.Results: Twenty-nine (56.86%) had eyelid skin...
The present study demonstrates capacity of α-MSH to augment recovery from ischemia/reperfusion (I/R)-induced retinal damage in vivo and correlation its protective effects with expression heme oxygenase-1 (HO-1). Used techniques include ocular ischemia reperfusion, electroretinography, histology, electron microscopy, molecular-biological techniques. results demonstrate the α-MSH-mediated inhibition I/R-induced functional deterioration retina. Outcomes suggest that occur mainly through...
AbstractAbstractObjectives: Relationship between hyperglycemia and stroke outcome is unclear, partly due to the small sample size in most studies, lack of consensus concerning cutoff level for hyperglycemia.Methods: In a cohort study, we investigated whether on-admission an independent predictor 30-day case fatality by analyzing data 2496 consecutive computed tomography (CT) verified acute ischemic patients (2077 non-diabetic 419 diabetic) included prospective, hospital-based Debrecen Stroke...
Systemic sclerosis is an autoimmune disease, characterized by widespread small vessel vasculopathy, immune dysregulation with production of autoantibodies, and progressive fibrosis. Changes in levels proangiogenic cytokines had already been determined largely serum. Our aim was to assess the VEGF human tears patients SSC.Forty-three (40 female 3 men, mean (SD) age 61 (48-74) years) SSc 27 healthy controls were enrolled this study. Basal tear sample collection velocity investigations carried...
To assess the accuracy of intraocular lens (IOL) power calculation based on three methods using artificial intelligence (AI) and one formula no AI.During cataract surgery 114 eyes, type IOL was implanted, calculated with Hill-RBF 2.0 method. The theoretical postoperative refractions were Kane Pearl-DGS a vergence (Barrett Universal II, BUII). differences between manifest objective predicted calculated. percentage eyes within ±0.5 D ±1.0 prediction error (PE), mean, median absolute errors...
Heme oxygenase-1 (HO-1) transgenic mice (Tg) were created using a rat HO-1 genomic transgene. Transgene expression was detected by RT-PCR and Western blots in the left ventricle (LV), right (RV) septum (S) mouse hearts, its function demonstrated elevated HO enzyme activity. Tg non-transgenic (NTg) hearts isolated subjected to ischemia/reperfusion. Significant post-ischemic recovery coronary flow (CF), aortic (AF), pressure (AOP) first derivative of AOP (AOPdp/dt) group compared NTg values....
Purpose: To evaluate detailed corneal parameters of inflammatory bowel disease (IBD) patients, including Crohn's (CD) and ulcerative colitis (UC) to assess associations between anterior segment values other clinical variables.Methods: This prospective cross-sectional case-control study at a tertiary referral center included 30 CD 36 UC patients 80 age- gender-matched controls with no ocular symptoms or surface disorders. All participants underwent comprehensive ophthalmological evaluation...
The efficacy of a crude hydro-alcoholic extract Cassia fistula (golden shower tree) fruit to protect the kidney against bromobenzene-induced toxicity was studied. Negative control mice received normal saline; positive were given 460 mg/kg bromobenzene; treated 200, 400, 600 and 800 followed by bromobenzene (daily oral gavage for 10 days). On 11th day, sacrificed, blood samples obtained assess urea nitrogen (BUN) creatinine levels, kidneys removed histological examination. We found that...
Among diabetes patients, ophthalmological complications are very frequent. High blood glucose and (consequential) ischemia-reperfusion (I/R) injury contribute significantly to the severity of retinopathies. Diabetic retinopathy is among leading causes blindness. Our study demonstrates effect sour cherry seed extract (SCSE) on function retina with electroretinography (ERG) in a diabetic setting or without Zucker Fatty (ZDF) rats. results prove that SCSE has retinoprotective rats: according...
Purpose: Corneal involvement in systemic sclerosis (SSc) is rare, but due to rich collagen composition cornea especially vulnerable connective tissue diseases. Therefore, our aim was evaluate corneal parameters of SSc patients.Methods: The study included 32 patients and 39 control subjects with no ocular symptoms or surface disorders. All participants underwent Pentacam evaluation objective signs dry eye disease (DED), clinical were evaluated.Results: pachymetric values, most the front...
Epiphora is commonly caused by a relative or complete occlusion in the lacrimal drainage system (LDS), principally nasolacrimal duct obstruction (NLDO). Dacryoscintigraphy (DSG), an extensively assessed imaging technique diagnosing its abnormalities, can provide only planar images, according to which it needs be improved. Our aim was evaluate clinical utility of simultaneous DSG and single-photon emission computed tomography/computed tomography (SPECT/CT) combined with tomographic...