Paul Symonds

ORCID: 0000-0001-9063-7395
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About
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Research Areas
  • Endometrial and Cervical Cancer Treatments
  • Cervical Cancer and HPV Research
  • Ovarian cancer diagnosis and treatment
  • Cancer survivorship and care
  • Effects of Radiation Exposure
  • Advanced Radiotherapy Techniques
  • Colorectal and Anal Carcinomas
  • Palliative Care and End-of-Life Issues
  • Bladder and Urothelial Cancer Treatments
  • Urinary and Genital Oncology Studies
  • Patient-Provider Communication in Healthcare
  • Prostate Cancer Diagnosis and Treatment
  • Radiation Therapy and Dosimetry
  • Lung Cancer Diagnosis and Treatment
  • Head and Neck Cancer Studies
  • Breast Cancer Treatment Studies
  • Uterine Myomas and Treatments
  • Advances in Oncology and Radiotherapy
  • Retinoids in leukemia and cellular processes
  • Global Cancer Incidence and Screening
  • Management of metastatic bone disease
  • Prostate Cancer Treatment and Research
  • Cancer Risks and Factors
  • Childhood Cancer Survivors' Quality of Life
  • Cancer Diagnosis and Treatment

University of Leicester
2013-2024

Leicester Royal Infirmary
2007-2021

Université de Sherbrooke
2018

University Hospitals of Leicester NHS Trust
2005-2014

Royal Preston Hospital
2011

The Christie NHS Foundation Trust
2011

Nottingham University Hospitals NHS Trust
2010

Nottingham City Hospital
2006

Cochrane
2005

Liverpool Women's Hospital
2005

<h3>Abstract</h3> <b>Objective</b>: To assess the needs of patients with cancer for information about their condition. <b>Design</b>: Cross sectional survey patients9 views by means semistructured interview questionnaire. <b>Setting</b>: A regional centre and two university hospitals in west Scotland. <b>Subjects</b>: 250 (93%) 269 invited to participate study who were selected age, sex, socioeconomic status, tumour site be representative <b>Main outcome measures</b>: Patients9 need know...

10.1136/bmj.313.7059.724 article EN BMJ 1996-09-21

BackgroundAlthough women with endometrial cancer generally have a favourable prognosis, those high-risk disease features are at increased risk of recurrence. The PORTEC-3 trial was initiated to investigate the benefit adjuvant chemotherapy during and after radiotherapy (chemoradiotherapy) versus pelvic alone for cancer.MethodsPORTEC-3 an open-label, international, randomised, phase 3 involving 103 centres in six clinical trials collaborating Gynaecological Cancer Intergroup. Eligible had...

10.1016/s1470-2045(18)30079-2 article EN cc-by The Lancet Oncology 2018-02-12

The PORTEC-3 trial investigated the benefit of combined adjuvant chemotherapy and radiotherapy versus pelvic alone for women with high-risk endometrial cancer. We updated analysis to investigate patterns recurrence did a post-hoc survival analysis.In multicentre randomised phase 3 trial, cancer were eligible if they had International Federation Gynaecology Obstetrics (FIGO) 2009 stage I, endometrioid grade deep myometrial invasion or lymphovascular space invasion, both; II III disease; I-III...

10.1016/s1470-2045(19)30395-x article EN cc-by The Lancet Oncology 2019-07-22

10.1016/s1470-2045(18)30566-7 article EN The Lancet Oncology 2018-11-06

The aim of this prospective, phase II trial was to determine the response muscle-invasive bladder cancer (MIBC) concurrent chemoradiotherapy weekly gemcitabine with 4 weeks radiotherapy (RT; GemX).

10.1200/jco.2010.31.5721 article EN Journal of Clinical Oncology 2011-01-05

Abstract Purpose : To examine the value of a new screening instrument in visual‐analogue format. Methods We report design and validation five‐dimensional tool called Emotion Thermometers (ET). This is combination five scales form four predictor domains (distress, anxiety, depression, anger) one outcome domain (need for help). Between March August 2007, 130 patients attending chemotherapy suite their first treatment were asked to complete several questionnaires with distress, anxiety...

10.1002/pon.1523 article EN Psycho-Oncology 2009-03-18

Despite documented high rates of psychological distress, it is not clear how to identify those who are willing accept help. The aim this study was investigate whether asking patients receiving chemotherapy if they want help with emotional problems valuable and the type want.Patients attending a suite were asked complete Hospital Anxiety Depression Scale, Brief Patient Health Questionnaire (PHQ) Emotion Thermometers tools. Results compared single question on desire for help.In study, 128...

10.1002/pon.1759 article EN Psycho-Oncology 2010-05-04

To compare survival and late complications between patients treated with chemoradiotherapy radiotherapy for locally advanced cervix cancer.A Royal College of Radiologists' audit in UK cancer centres 2001-2002. Survival, recurrence were assessed grouped according to radical treatment received (radiotherapy, chemoradiotherapy, postoperative or chemoradiotherapy) non-radical treatment. Late complication rates using the Franco-Italian glossary.Data analysed 1243 from 42 centres. Overall 5-year...

10.1016/j.clon.2010.06.002 article EN cc-by Clinical Oncology 2010-07-02

Abstract BACKGROUND: There is considerable uncertainty regarding the acceptability of routine distress screening. METHODS: In an unfunded implementation study, authors asked 50 clinicians (chemotherapy nurses and treatment radiographers/radiation technologists) to implement a screening program for as part care record their feedback after each clinical encounter. total, 379 patients were screened using simple paper‐and‐pencil versions thermometer emotion (ET). RESULTS: Across all...

10.1002/cncr.27648 article EN Cancer 2012-06-06

Abstract Purpose : To examine the added value of an algorithmic combination visual‐analogue thermometers compared with Distress Thermometer (DT) when attempting to detect depression, anxiety or distress in early cancer. Methods We report Classification and Regression Tree logistic regression analyses new five‐domain Emotion Thermometers tool. This is a five scales form four mood domains (distress, anxiety, anger) as well need for help. 130 patients attending their first chemotherapy...

10.1002/pon.1557 article EN Psycho-Oncology 2009-03-18

Abstract Background : There is uncertainty regarding how well clinical nurse specialists are able to identify distress in cancer settings. Methods We examined recognition of patient‐reported by across three sites the East Midlands (UK). Clinicians were asked report on their opinion presence or any mental health complication after routine assessment 401 mixed patients. Patient‐reported was defined thermometer at a cut‐off 4 higher. Results found that prevalence 45.4%. The rates for mild,...

10.1002/pon.1815 article EN Psycho-Oncology 2010-08-05
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