A5064468544- Animal Ecology and Behavior Studies
- Renal Transplantation Outcomes and Treatments
- Genetic diversity and population structure
- Endometrial and Cervical Cancer Treatments
- Organ Donation and Transplantation
- Ovarian cancer diagnosis and treatment
- Trypanosoma species research and implications
- Yersinia bacterium, plague, ectoparasites research
- Organ Transplantation Techniques and Outcomes
- Cervical Cancer and HPV Research
- Zoonotic diseases and public health
- Viral Infections and Vectors
- Cancer Genomics and Diagnostics
- Parasite Biology and Host Interactions
- Wildlife Ecology and Conservation
- Parasites and Host Interactions
- Intraperitoneal and Appendiceal Malignancies
- Renal Diseases and Glomerulopathies
- Mosquito-borne diseases and control
- Leptospirosis research and findings
- Vector-Borne Animal Diseases
- Endometriosis Research and Treatment
- Renal and related cancers
- Transplantation: Methods and Outcomes
- Evolution and Paleontology Studies
Natera (United States)
2020-2024
Centre de Biologie et de Gestion des Populations
2013-2024
Agropolis International
2015-2024
The Metabolomics Innovation Centre
2024
Institut Agro Montpellier
2012-2023
Institut de Recherche pour le Développement
2013-2023
Centre de Coopération Internationale en Recherche Agronomique pour le Développement
2013-2023
Université de Montpellier
2017-2023
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2021-2023
L'Institut Agro
2023
Abstract Microsatellites (or SSRs: simple sequence repeats) are among the most frequently used DNA markers in many areas of research. The use microsatellite is limited by difficulties involved their de novo isolation from species for which no genomic resources available. We describe here a high‐throughput method isolating based on coupling multiplex enrichment and next‐generation sequencing 454 GS‐FLX Titanium platforms. procedure was calibrated model ( Apis mellifera ) validated 13 other...
This pilot study aimed to provide supportive evidence for the acceptability and usefulness of Meaning-Making intervention (MMi) in patients newly diagnosed with Stage III or IV ovarian cancer, estimates parameters needed design a full-scale study.A randomized controlled trial 24 (12 experimental 12 control) was conducted. Existential well-being (primary outcome), overall quality life, distress, anxiety, depression self-efficacy were measured.Compared control group, group had better sense...
Standard-of-care biomarkers for renal allograft rejection are lagging indicators, signaling existing organ injury. This precludes early intervention, when immunological cascades leading to most susceptible. Donor-derived cell-free DNA (dd-cfDNA) shows promise as an indicator of rejection, allowing earlier and possibly more effective treatment. analysis was designed assess this using real-world dd-cfDNA testing evidence.
Cercarial emission of schistosomes is a determinant in the transmission to definitive host and constitutes good marker identify which responsible for transmission, mainly introgressive hybridization situations. Our goal was test hypothesis that micro-mammals play role Schistosoma haematobium, S. bovis, and/or haematobium x bovis transmission. Small mammal sampling conducted seven semi-lacustrine villages southern Benin. Among 62 animals trapped, 50 individuals were investigated adults eggs:...
Trifecta (ClinicalTrials.gov #NCT04239703) is a prospective trial defining relationships between donor-derived cell-free DNA (dd-cfDNA), donor-specific antibody (DSA), and molecular findings in kidney transplant biopsies. Previous analyses of double results showed dd-cfDNA was strongly associated with rejection-associated molecules the biopsy. The present study analyzed triple 280 biopsies, focusing on question levels DSA-negative antibody-mediated rejection (AMR).
BACKGROUND: Partial Rh antigens have been widely described in black individuals. Carriers are prone to immunization when exposed the normal antigens. In sickle cell disease (SCD), patient alloimmunization is a major cause of transfusion failure. The potential individuals with partial C antigen make anti‐C has not investigated. We sought status and production cohort SCD patients C+ phenotype, determine whether exposure should be avoided. STUDY DESIGN AND METHODS: constituted 177 randomly...
There are two types of approaches to regenerate tissues: cell-based and cell-free. The former approach is introduce exogenous cells into the host tissues, latter use materials other than in an attempt tissues. has been a significant advancement stem pulp dentin regeneration research past few years. Studies small large animals have demonstrated that pulp/dentin-like tissues can be regenerated partially or completely root canal space with apical openings 0.7-3.0 mm using dental cells,...
Pancreas graft status in simultaneous pancreas-kidney transplant (SPKTx) is currently assessed by nonspecific biochemical markers, typically amylase or lipase. Identifying a noninvasive biomarker with good sensitivity detecting early pancreas rejection could improve SPKTx management.Here, we developed pilot study to explore donor-derived cell-free DNA (dd-cfDNA) performance predicting biopsy-proven acute (P-BPAR) of the cohort 36 recipients biopsy-matched plasma samples. dd-cfDNA was...
A growing number of studies has highlighted the importance coinfections in eco‐evolutionary processes underlying host–parasite interactions and resulting epidemiology zoonotic agents. Small mammals, particularly rodents, are known to be important reservoirs many pathogens, such as Toxoplasma gondii Trypanosoma lewisi , that responsible for toxoplasmosis atypical trypanosomiasis humans, respectively. Laboratory experiments on rodent models have shown primary infection with T. increases host...
This article documents the addition of 238 microsatellite marker loci and 72 pairs Single Nucleotide Polymorphism (SNP) sequencing primers to Molecular Ecology Resources Database. Loci were developed for following species: Adelges tsugae, Artemisia tridentata, Astroides calycularis, Azorella selago, Botryllus schlosseri, Botrylloides violaceus, Cardiocrinum cordatum var. glehnii, Campylopterus curvipennis, Colocasia esculenta, Cynomys ludovicianus, leucurus, gunnisoni, Epinephelus coioides,...
The identification of pathogenic variants in genes associated with chronic kidney disease can provide patients and nephrologists actionable information to guide diagnoses therapeutic plans. However, many do not use genetic testing despite costs decreasing over time more widespread availability.We conducted a survey uncover the perceptions general adult about utility barriers clinical practice.The online was administered board-certified (n = 10,054) United States.We analyzed demographic...
Among all biopsies in the Trifecta-Kidney Study ( ClinicalTrials.gov NCT04239703), elevated plasma donor-derived cell-free DNA (dd-cfDNA) correlated most strongly with molecular antibody-mediated rejection (AMR) but was also other states: T cell-mediated (TCMR), acute kidney injury (AKI), and some apparently normal biopsies. The present study aimed to define correlates of dd-cfDNA within specific states.
Abstract Rodents of the Praomys daltoni complex are typical inhabitants Sudanian savanna ecosystem in western Africa and represent a suitable model for testing effects Quaternary climatic oscillations on extant genetic variation patterns. Phylogeographical analyses mitochondrial DNA sequences (cytochrome b ) across distribution range revealed several well‐defined clades that do not support division clade into two species currently recognized basis morphology, i.e. P. (Thomas, 1892) derooi (...
A phylogeographic study was conducted on the Nile grass rat, Arvicanthis niloticus, a rodent species that is tightly associated with open grasslands from Sudano-Sahelian regions. Using one mitochondrial (cytochrome b) and nuclear (intron 7 of Beta Fibrinogen) gene, robust patterns were retrieved clearly show (i) originated in East Africa concomitantly expanding some 2 Ma, (ii) four parapatric genetically well-defined lineages differentiated essentially to West following Pleistocene...
Invasive rodents have been responsible for the diffusion worldwide of many zoonotic agents, thus representing major threats public health. Cities are important hubs people and goods exchange expected to play a pivotal role in invasive commensal rodent dissemination. Yet, data about urban rodents' ecology, especially vs. native species interactions, dramatically scarce. Here, we provide results an extensive survey conducted Niamey, Niger, depicting early stages bioinvasions within city. We...
Based on compiled small mammal trapping data collected over 12 years from Benin and Niger (3701 individual records 66 sampling sites), located in mainland Africa, we here describe the community assemblage urban habitats along commercial axis connecting two countries, seaport of Cotonou to Sahelian hinterland, with a particular focus invasive species. In doing so, document extant species distributions, which highlight risks continuing range expansion three synanthropic rodent species, namely...
Abstract Leptospirosis is a zoonotic disease that caused by spirochete bacteria of the genus Leptospira. Around world, one million people each year are infected, leading to 60,000 deaths. Infection occurs through contact with environmental pathogens excreted mammals (notably rodents). Data on Leptospira and leptospirosis in Africa rather scarce, especially urban habitats though these appear be favourable environments for pathogen circulation human contamination. Using qPCR, DNA sequencing as...