A5043770040- Infant Development and Preterm Care
- Neonatal Respiratory Health Research
- Birth, Development, and Health
- Infant Nutrition and Health
- Neonatal and fetal brain pathology
- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Urticaria and Related Conditions
- Mast cells and histamine
- Material Properties and Processing
- Assisted Reproductive Technology and Twin Pregnancy
- Surfactants and Colloidal Systems
- Pregnancy and preeclampsia studies
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Advanced Polymer Synthesis and Characterization
- Maternal Mental Health During Pregnancy and Postpartum
University Medical Center Groningen
2011-2025
University of Groningen
2012-2023
Beatrix Kinderziekenhuis
2016
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2015
Research Network (United States)
2015
RELX Group (Netherlands)
2015
Pediatrics and Genetics
2011-2013
Hersenstichting
2013
The Royal Children's Hospital Foundation
2013
BACKGROUND AND OBJECTIVE: Children born moderately preterm (32–356/7 weeks’ gestation) are at increased risk of both neonatal morbidities and developmental delays in early childhood. It is unknown whether contribute to the delay. The objective this study was determine effect after birth on development preschool age. METHODS: In a community-based, stratified cohort, parents 832 children 2002 or 2003 completed Ages Stage Questionnaire when their child 43 49 months old. Data Apgar scores,...
The aim of the study was to assess influence decreasing gestational age on risk developmental delay in various domains at 4 years among children born a wide range ages.In community-based cohort, parents 1439 preterm-born (24 0/7 35 6/7 wks) and 544 term-born (38 41 wks') 2002 2003 completed Ages Stages Questionnaire (ASQ) when their child 3 7 months 1 month old. prevalence rates abnormal scores ASQ-total problems scale were compared preterm resulting odds ratios for groups calculated...
OBJECTIVE: To describe growth in moderately preterm-born children, determine the prevalence of restraint at age 4, and identify predictors restraint. We hypothesized that children differs from term-born is more prevalent those born prematurely. PATIENTS AND METHODS: This was a community-based cohort study 1123 prematurely (gestational [GA]: 32–3567 weeks) between January 2002 June 2003. RESULTS: On average, we found were shorter weighed less each assessment during first 4 years life than...
β-Blockers have shown promising effects in preventing aquagenic pruritus, but they may also a role urticaria and aquadynia. The question arises as to whether aquadynia, should be considered distinct phenotypes or part of disease continuum.
To estimate the association between pre-existing maternal and pregnancy-related factors developmental delay in early childhood moderately preterm-born children.We measured development with Ages Stages Questionnaire at age 43-49 months 834 (between 32 0/7 35 6/7 weeks of gestation) children born 2002-2003. We obtained data on preexisting maternal, pregnancy-related, fetal, delivery-related factors. calculated odds ratios (ORs) 95% confidence intervals (CIs) attributable risks for adjusted...
To determine how symmetric (proportionate; SGR) and asymmetric (disproportionate; AGR) growth restriction influence development in preterms from birth to 4 years.This community-based cohort study of 810 children comprised 86 SGR, 61 AGR, 663 non-growth restricted (NGR) preterms, born 2002 2003. Symmetrical was defined as a weight below the 16th percentile (-1 SD) compared with full-terms head circumference (HC) z score not exceeding infant's by >1 SD. Asymmetric HC that for SD proxy brain...
<b><i>Background:</i></b> Fullterm small-for-gestational-age children (SGAs) are known for their ability to catch up on growth. Nevertheless, increased risk of growth restriction remains. Evidence preterm SGA children's is lacking. <b><i>Objective:</i></b> To determine absolute gains in height and weight, relative growth, SGAs from 0 4 years how prematurity status affect these measures. <b><i>Design/Methods:</i></b>...
To determine the association between longitudinal growth measures (height, weight, head circumference, and extent of catch-up growth) neuropsychological functioning at 7 years in moderately late preterm children.This study was part a prospective, community-based cohort study. Data on were obtained from records routine assessments well-child centers until age 4 research setting years. Neuropsychological assessed We associations with determined odds ratios for impaired functioning. All...
Objectives Moderately and late preterm children (MLPs, 32.0–36.9 weeks gestational age) have a greater risk of poorer growth. This seems to be associated with neuropsychological functioning. Evidence is limited on whether this also holds for emotional behavioral (EB) problems. Therefore, we assessed longitudinal growth from birth until age 7 was EB problems at in MLPs. Study design study part the Longitudinal Preterm Outcome Project, prospective cohort study. Data (height, weight, head...
To determine how growth of large for gestational age (LGA) preterm (PT) children was affected by their PT birth and LGA status.This is a community-based cohort study 1302 489 full-term (FT) children, born 2002 2003.We found that in height, weight, head circumference well balanced during infancy only weight gain accelerated subsequent years. This led to high BMIs comparable those FT children. Being both resulted median at the 4 years 0.1 SD lower (P = .44), height .48), 0.5 compared with...
Mastocytosis is a clonal disorder characterized by the proliferation and accumulation of mast cells (MCs) in various tissue types, preferentially skin bone marrow (BM). consists cutaneous systemic forms both pediatric adult patients. Both excess increased propensity MCs to release mediators leads higher frequency severity immediate hypersensitivity reactions.1-4 In peri-operative setting, mastocytosis associated with risk severe anaphylaxis.1-7 Here, drugs such as nonsteroidal...
Clinical implications:A vertebral fracture after a minimal trauma, has not been described previously in child with indolent systemic mastocytosis.Children mastocytosis are probably susceptible to osteoporotic manifestations and fractures, especially of the spine, as adults.Mastocytosis is clonal disorder, characterized by accumulation pathological mast cells. 1 This may only be present skin (cutaneous (CM)), but involve other organs well, specifically bone marrow (systemic (SM)).