A5048171657- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Head and Neck Cancer Studies
- Advanced Radiotherapy Techniques
- Lung Cancer Research Studies
- Esophageal Cancer Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Medical Imaging and Pathology Studies
- Gastric Cancer Management and Outcomes
- Cardiac tumors and thrombi
- PI3K/AKT/mTOR signaling in cancer
- Metabolism, Diabetes, and Cancer
- Head and Neck Surgical Oncology
- Multiple and Secondary Primary Cancers
- Advances in Oncology and Radiotherapy
- Colorectal Cancer Treatments and Studies
- Cancer, Lipids, and Metabolism
The Netherlands Cancer Institute
2013-2025
Radiation Oncology Associates
2019
Oncode Institute
2013
Abstract Background: The phase I Induction trial (NCT04287894) assessed the feasibility and safety of induction immunotherapy (IIT) prior to concurrent chemoradiotherapy (cCRT) in patients with locally advanced non-small cell lung cancer (NSCLC). Methods: Patients unresectable stage II/III NSCLC were eligible for inclusion. received either one cycle tremelimumab (75mg) two cycles durvalumab (1500mg) cohort I, (300mg) II or III. After IIT, a comprehensive radiological pathological restaging...
<p>Supplementary Figure S5: Post-IIT ADC 0-50-800 relative to baseline of matched lymph nodes (baseline pathologic sampled tumor positive also post-IIT, median 106% vs 144%, p=0.20). Abbreviations: ADC, apparent diffusion coefficient; path, pathology.</p>
<div>AbstractPurpose:<p>The phase I induction trial (NCT04287894) assessed the feasibility and safety of immunotherapy (IIT) prior to concurrent chemoradiotherapy (cCRT) in patients with locally advanced non–small cell lung cancer (NSCLC).</p>Patients Methods:<p>Patients unresectable stage II/III NSCLC were eligible for inclusion. Patients received either one cycle tremelimumab (75 mg) two cycles durvalumab (1,500 cohort I, (300 II, or III. After IIT, a comprehensive...
<p>Supplementary Figure S4: Post-IIT ADC relative to baseline of downstaged and not-downstaged patients (median 112% vs 113%, p=0.94). Abbreviation: ADC, apparent diffusion coefficient.</p>
<p>Supplementary Figure S3: Post-IIT TLG of matched lymph nodes (baseline pathologic sampled tumor positive also post-IIT) (median 11.3 vs 0, p=0.04). Abbreviations: TLG, total lesion glycolysis; g, grams; path, pathology.</p>
<p>Supplementary Figure S1: Sankey diagram of TNM stage at baseline and after IIT. Numbers depict number patients per category.</p>
<p>Supplementary Figure S2: Baseline TLG of baseline pathologic sampled lymph nodes (median 19.4 vs 6.2, p=0.02). Abbreviations: TLG, total lesion glycolysis; g, grams; path, pathology.</p>
Introduction Nasopharyngeal carcinoma (NPC) has a high incidence in Indonesia. Previous study Yogyakarta revealed complete response of 29% and median overall survival less than 2 years. These poor treatment outcome are influenced by the long diagnose-to-treatment interval to radiotherapy (DTI) extended time (OTT). This reveals insight why OTT DTI prolonged. Method All patients treated with curative intent for NPC between July 2011 until October 2012 were included. During daily diary was...
A minimally invasive lobectomy (MIL) is the standard treatment for stage I non-small cell lung cancer (NSCLC) in medically operable patients. Stereotactic ablative radiotherapy (SABR) recommended inoperable patients and has been proposed as a potential alternative well. Here, we present results of feasibility study preparation nationwide retrospective cohort study, comparing outcomes between both modalities.In this data from with clinical NSCLC treated MIL or SABR 2014-2015 were retrieved...
Objective: The objective of this study was to determine the volumetric change in thyroid gland nasopharyngeal carcinoma patients after undergoing chemoradiotherapy that could alter function. Furthermore, correlates mean dose effect towards decrease volume predict outcoming clinical signs radiation induced hypothyroidism (RHT). Methods: This consists a cross sectional retrospective evaluation multiplanar image comprised three planes axial, coronal, and sagittal all NPC who underwent received...