A5103222976- Healthcare Regulation
- Antibiotic Use and Resistance
- Public Health in Brazil
- Bacterial Identification and Susceptibility Testing
- Nosocomial Infections in ICU
- Infection Control in Healthcare
- Tuberculosis Research and Epidemiology
- Health, Nursing, Elderly Care
- Fungal Infections and Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Antimicrobial Resistance in Staphylococcus
- Antifungal resistance and susceptibility
- Surgical site infection prevention
- Maternal and Neonatal Healthcare
- Antibiotic Resistance in Bacteria
- Central Venous Catheters and Hemodialysis
- Respiratory Support and Mechanisms
- Neutropenia and Cancer Infections
- Cardiac, Anesthesia and Surgical Outcomes
- Nail Diseases and Treatments
- Cystic Fibrosis Research Advances
- Health Education and Validation
- Urinary Tract Infections Management
- Respiratory viral infections research
- Mycobacterium research and diagnosis
Hospital de Clínicas de Porto Alegre
2011-2022
Universidade Federal do Rio de Janeiro
2003-2019
Universidade Estadual de Santa Cruz
2019
Fundação Universitária de Cardiologia
2009-2019
Hospital de Clínicas
2013-2018
Universidade Federal do Rio Grande do Sul
2007-2016
Instituto do Cérebro
2016
Purdue University West Lafayette
2008
Universidade Federal do Paraná
2008
University of Illinois Urbana-Champaign
2008
Background. It is unknown whether rising incidence rates of nosocomial bloodstream infections (BSIs) caused by antibiotic-resistant bacteria (ARB) replace antibiotic-susceptible (ASB), leaving the total BSI rate unaffected. Methods. We investigated temporal trends in annual densities (events per 100 000 patient-days) BSIs methicillin-resistant Staphylococcus aureus (MRSA), ARB other than MRSA, and ASB 7 ARB-endemic ARB-nonendemic hospitals between 1998 2007. Results. 33 130 (14% ARB) yielded...
Abstract Hemotrophic mycoplasmas infect a variety of mammals. Although infection in humans is rarely reported, an association with immunocompromised state has been suggested. We report case Mycoplasma haemofelis–like HIV-positive patient co-infected Bartonella henselae.
Abstract Background Initial management of chemotherapy-induced febrile neutropaenia (FN) comprises empirical therapy with a broad-spectrum antimicrobial. Currently, there is sufficient evidence to indicate which antibiotic regimen should be administered initially. However, no randomized trial has evaluated whether adherence an antimicrobial stewardship program (ASP) results in lower rates mortality this setting. The present study sought assess the association between ASP and among...
Surveillance of hospital-acquired infections (HAIs) is the foundation infection control. Machine learning (ML) has been demonstrated to be a valuable tool for HAI surveillance. We compared manual surveillance with supervised, semiautomated, ML method, and we explored types features importance depicted by model.
HIV subtype C is the most prevalent in world. Despite its recent expansion Brazil, HIV-1C already prevails southernmost state of Rio Grande do Sul. This unique epidemiology has prompted us to characterize that population. Seventy-seven HIV-1–infected subjects attending largest HIV/AIDS clinic had protease and reverse transcriptase (RT) genes their virus subtyped genotyped. When subtype-specific infections were plotted according year diagnosis, prevalence was shown increase over last 18 years...
In this study we propose the use of text mining and machine learning methods to predict detect Surgical Site Infections (SSIs) using textual descriptions surgeries post-operative patients' records, mined from database a high complexity University hospital. SSIs are among most common adverse events experienced by hospitalized patients; preventing such is fundamental ensure safety. Knowledge on SSI occurrence rates may also be useful in future episodes. We analyzed 15,479 surgery records...
Surgical site infections (SSI) are among the most prevalent in healthcare institutions, attributing a risk of death which varies from 33% to 77% and 2- 11-fold increase death. Patients submitted cardiac surgery more susceptible SSI, accounting for 3.5% 21% SSI. The mortality rate attributable these causes is as high 25%. Prevention SSI based on bundle preventive measures, focus modifiable risks.
DEFININDO" PNEUMONIA ASSOCIADA À VENTILAÇÃO MECÂNICAA pneumonia associada à ventilação mecânica (PAVM) é a infecção nosocomial mais comum no ambiente de cuidados intensivos.Tem prevalência variável, com taxas desde 6 até 50 casos por 100 admissões na unidade terapia intensiva (UTI). (1,2)Tal variabilidade se deve principalmente dois aspectos: presença diferentes case-mix em unidades avaliadas literatura e inexistência critérios diagnósticos precisos que permitam um diagnóstico operacional...
We developed an antimicrobial stewardship programme, based on telemedicine, for a remote community hospital in southern Brazil. Expertise infectious diseases was provided from 250-bed tertiary cardiology patients located 575 km away. At the hospital, prescriptions were completed via secure web site. A written reply sent back to prescriber by email and SMS text message. During 4-month study period there 81 76 patients. Most (67%) respiratory infections. Ampicillin prescribed 44% of cases (n =...
BACKGROUND: Coagulase‐negative staphylococci (CoNS) are currently the most common isolates recovered from blood of patients with cancer and febrile neutropenia (FN). OBJECTIVES:To assess mortality associated bloodstream infections (BSIs) caused by CoNS in FN. METHODS: A prospective cohort study was conducted a single tertiary hospital October 2009 to August 2011. Follow‐ups were performed on all adult who admitted hematology ward Bacteremia defined as two positive results independent...
Respiratory syncytial virus (RSV) is the main cause of lower respiratory tract illness in children worldwide. Molecular analyses show two distinct RSV groups (A and B) that comprise different genotypes. This variability contributes to capacity yearly outbreaks. These genotypes circulate within community hospital wards. currently leading nosocomial infections pediatric populations. The aim this study was evaluate G protein gene diversity amplicons. Nasopharyngeal aspirate samples were...
Healthcare-associated infections (HAIs) are among the most common adverse events in hospitals. We used artificial intelligence (AI) algorithms for infection surveillance a cohort study. The model correctly detected 67 out of 73 patients with HAIs. final multilayer perceptron neural network achieving an area under receiver operating curve (AUROC) 90.27%; specificity 78.86%; sensitivity 88.57%. Respiratory had best results (AUROC ≥93.47%). AI algorithm could identify is feasible method HAI...
To evaluate the impact of ertapenem use in Pseudomonas aeruginosa carbapenem resistance, taking into account volume antimicrobial consumption, consumption by entire hospital alcohol-based antiseptic hand rub, and density rate invasive practices.Before-and-after trial.A tertiary care university southern Brazil.Ertapenem was first added to formulary June 2006, it excluded February 2009. We evaluated resistance rates through 3 study periods: period 1, before (17 months); 2, during (33 3, after...
Introduction Telemedicine technologies are increasingly being incorporated into infectious disease practice. We aimed to demonstrate the impact of antimicrobial stewardship through telemedicine on bacterial resistance rates. Methods conducted a quasi-experimental study in 220-bed hospital southern Brazil. An program incorporating use was implemented. Resistance and consumption rates were determined analysed using segmented regression model. Results After intervention, rate appropriate...
Disseminated mycobacterial disease is an important cause of morbidity and mortality in patients with HIV-infection. Nonspecific clinical presentation makes the diagnosis difficult sometimes neglected. We conducted a retrospective cohort study to compare disseminated Mycobacterial tuberculosis (MTB) non-tuberculous (NTM) HIV-positive from 1996 2006 Brazil. Tuberculosis (TB) was diagnosed 65 (67.7%) NTM 31 (32.3%) patients. Patients had lower CD4 T cells counts (median 13.0 cells/mm3 versus...
The Gram stain can be used to direct initial empiric antimicrobial therapy when complete culture is not available. This rapid test could prevent the initiation of inappropriate and adverse outcomes. However, several studies have attempted determine value in diagnosis bacterial infection different populations patients with ventilator-associated pneumonia (VAP) conflicting results. objective this study evaluate accuracy predicting existence Staphylococcus aureus infections from cultures...
Vancomycin-resistant Enterococcus faecium (VREF) has emerged as a relevant multidrug-resistant pathogen and potentially lethal etiology of health care associated infections worldwide. The objective this retrospective cohort study was to assess factors with mortality in patients VREF bacteremia major tertiary referral hospital Southern Brazil. All documented cases identified between May 2010 July 2012 were evaluated. Cox regression performed determine whether the characteristics related host...