Luciana de Souza Nunes

ORCID: 0000-0003-3437-0256
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About
Contact & Profiles
Research Areas
  • Mycobacterium research and diagnosis
  • Tuberculosis Research and Epidemiology
  • Infectious Diseases and Mycology
  • Infectious Diseases and Tuberculosis
  • Antibiotic Resistance in Bacteria
  • Respiratory viral infections research
  • Science and Education Research
  • Cystic Fibrosis Research Advances
  • Viral Infections and Outbreaks Research
  • Neonatal and Maternal Infections
  • Viral gastroenteritis research and epidemiology
  • Antibiotic Use and Resistance
  • Agricultural and Food Sciences
  • Youth, Drugs, and Violence
  • Streptococcal Infections and Treatments
  • Liver Disease Diagnosis and Treatment
  • Alcohol Consumption and Health Effects
  • Physical Education and Sports Studies
  • Physical Education and Gymnastics
  • Leprosy Research and Treatment
  • Nosocomial Infections in ICU
  • Bacterial Genetics and Biotechnology
  • Maternal and Neonatal Healthcare
  • Infectious Disease Case Reports and Treatments
  • Urologic and reproductive health conditions

Promotora de Informaciones (Spain)
2023

Universidade Federal do Pampa
2017-2022

Hospital São Rafael
2022

Universidade de Santa Cruz do Sul
2016-2018

Hospital de Clínicas de Porto Alegre
2014-2018

Universidade Federal do Rio Grande do Sul
2012-2017

Centre International de Recherche sur le Cancer
2014

University Hospital Heidelberg
2013

Centre for Addiction and Mental Health
2013

University of the Witwatersrand
2013

There is limited evidence for an association between the pattern of lifetime alcohol use and cause-specific risk death.Multivariable hazard ratios were estimated different causes death according to patterns consumption using a competing risks approach: 111 953 men 268 442 women from eight countries participating in European Prospective Investigation into Cancer Nutrition (EPIC) study included. Self-reported at ages 20, 30, 40 or 50 years enrollment used analysis; 26 411 deaths observed...

10.1093/ije/dyt154 article EN International Journal of Epidemiology 2013-12-01

ABSTRACT Objective: The incidence of lung disease caused by nontuberculous mycobacteria (NTM) has been increasing worldwide. In Brazil, there are few studies about mycobacterial (NTMLD), and its prevalence is yet to be known. Our objective was determine the specific etiology in state Rio Grande do Sul, as well frequency diversity NTM species our sample patients. Methods: This a retrospective analysis medical records patients diagnosed with NTMLD treated referral center located city Porto...

10.1590/s1806-37562017000000213 article EN cc-by-nc Jornal Brasileiro de Pneumologia 2018-04-01

ABSTRACT Worldwide, nontuberculous mycobacteria (NTM) have become emergent pathogens of pulmonary infections in cystic fibrosis (CF) patients, with an estimated prevalence ranging from 5 to 20%. This work investigated the presence NTM sputum samples 129 CF patients (2 18 years old) submitted longitudinal clinical supervision at a regional reference center Rio de Janeiro, Brazil. From June 2009 March 2012, 36 isolates recovered 10 (7.75%) out children were obtained. Molecular identification...

10.1128/jcm.00549-14 article EN Journal of Clinical Microbiology 2014-06-12

Introduction: The present study aimed to assess the antibiotic resistance profiles and detect presence of sul2 gene in sulfamethoxazole-susceptible resistant isolates Escherichia coli obtained from outpatients inpatients with urinary tract infections. Methodology: 739 strains were assessed 100 was tested. Results: antibiotics highest rates ampicillin (57.4%) trimethoprim-sulfamethoxazole (44.7%). detected 66.7% outpatient samples 67.9% inpatient samples. Conclusions: Our results demonstrate...

10.3855/jidc.3380 article EN cc-by The Journal of Infection in Developing Countries 2014-01-15

Respiratory syncytial virus (RSV) is the main cause of lower respiratory tract illness in children worldwide. Molecular analyses show two distinct RSV groups (A and B) that comprise different genotypes. This variability contributes to capacity yearly outbreaks. These genotypes circulate within community hospital wards. currently leading nosocomial infections pediatric populations. The aim this study was evaluate G protein gene diversity amplicons. Nasopharyngeal aspirate samples were...

10.1186/1743-422x-11-36 article EN cc-by Virology Journal 2014-02-24

Outbreaks associated with rapidly growing mycobacteria (RGM) have been increasingly reported worldwide, including in Brazil. Among the RGM, Mycobacterium abscessus complex is most pathogenic and related to multidrug resistance. The aim of this study was evaluate antimicrobial susceptibility molecular profile RGM isolates involved new postsurgical infection outbreaks Brazil since 2007. Of 109 cases state Rio Grande do Sul between 2007 2011, 43 (39 %) had confirmed mycobacterial growth...

10.1099/jmm.0.074906-0 article EN Journal of Medical Microbiology 2014-07-19

Rapid identification of drug resistance in clinical isolates Mycobacterium tuberculosis is important determining treatment for tuberculosis. The aim this work was evaluate the performance GenoType MDRTBplus assay directly on sputum patients who had failure or relapse a routine outpatient setting southern Brazil.

10.1128/jcm.00364-13 article EN Journal of Clinical Microbiology 2013-03-07

Viruses are major contributors to acute respiratory infection-related morbidity and mortality worldwide. The influenza (IF) viruses human syncytial virus (RSV) play a particularly important role in the etiology of infections. This study sought standardize one-step duplex real-time RT-PCR technique optimize diagnosis IFA/IFB RSVA/RSVB infection. Viral RNA was extracted with commercially available QIAamp Mini Kit according manufacturer instructions. performed primers matrix protein gene IFA,...

10.1016/j.jviromet.2012.07.008 article EN publisher-specific-oa Journal of Virological Methods 2012-07-13

ABSTRACT We conducted a cross-sectional, retrospective study, characterized by classical and molecular epidemiology, involving M. tuberculosis isolates from regional prison in southern Brazil. Between January of 2011 August 2014, 379 prisoners underwent sputum smear microscopy culture; 53 (13.9%) were diagnosed with active tuberculosis. Of those, 8 (22.9%) presented isoniazid-resistant Strain genotyping was carried out 15-locus mycobacterial interspersed repetitive unit-variable-number...

10.1590/s1806-37562016000000023 article EN cc-by-nc Jornal Brasileiro de Pneumologia 2016-08-01

Mycobacterium abscessus complex (MABC) includes species with high resistance rates among mycobacterial pathogens. In fact, MABC infections may not respond to clarithromycin treatment, which has historically been very effective against infection. Molecular markers have proposed detect both acquired (rrl polymorphisms) and inducible (erm(41) in isolates.This study aimed evaluate the susceptibility profile molecular of MABC.The was determined by broth microdilution reads on days 3, 5, 7 14....

10.1590/0074-02760170080 article EN cc-by Memórias do Instituto Oswaldo Cruz 2017-10-30

Group B Streptococcus is a causative agent of invasive neonatal infections. Maternal colonization by agalactiae necessary condition for vertical transmission, with efficient screening pregnant women playing an essential role in the prevention In this study, we aimed to compare performance conventional polymerase chain reaction and real-time PCR assays as methods S. against microbiological culture method considered gold-standard. A total 130 samples from were analyzed sensitivity,...

10.1016/j.bjid.2018.09.005 article EN cc-by-nc-nd The Brazilian Journal of Infectious Diseases 2018-11-01

ABSTRACT Objective: to evaluate the risk of infection and illness caused by Mycobacterium tuberculosis among health care security staff in prisons two regions Rio Grande do Sul (RS). Method: cross-sectional study involving prison staff. An interview sputum smear microscopy culture were performed. Latent was evaluated according result tuberculin test (TT), self-referred. Results: who had a TT, 10 (83.3%) central region 2 (16.7%) southern considered reactors. Length employment officers reacted...

10.1590/0034-7167-2016-0012 article EN cc-by Revista Brasileira de Enfermagem 2017-04-01

Historically, qualitative research has complemented quantitative biologic and epidemiologic studies to provide a more complete understanding of pandemics. The COVID-19 pandemic generated unique novel challenges for researchers, who have embraced creative solutions including virtual focus groups rapid analyses continue their work. We present our experience conducting multilingual global study healthcare resilience among teams pediatric oncology professionals during the pandemic. an in-depth...

10.1177/23333936221080969 article EN cc-by-nc Global Qualitative Nursing Research 2022-01-01

BACKGROUND To cope with the emergence of multidrug-resistant tuberculosis (MDR-TB), new molecular methods that can routinely be used to screen for a wide range drug resistance related genetic markers in Mycobacterium genome are urgently needed. OBJECTIVE evaluate performance multiplex ligaton-dependent probe amplification (MLPA) against Genotype® MTBDRplus detect isoniazid (INHr) and rifampicin (RIFr). METHOD 96 culture isolates characterised identification, susceptibility testing (DST)...

10.1590/0074-02760160376 article EN cc-by Memórias do Instituto Oswaldo Cruz 2017-06-01

The aim of this study was to evaluate the relationship between antimicrobial susceptibility and genotype a Mycobacterium abscessus subsp. massiliense isolate obtained from respiratory tract patient in southern Brazil.The (named Myco1POA) submitted whole-genome sequencing using an Illumina MiSeq platform. Data were analysed Trim Galore!, SPAdes Genome Assembler, Geneious BioEdit software. Multilocus sequence typing (MLST) performed by silico analysis seven housekeeping genes according...

10.1016/j.jgar.2020.04.030 article EN cc-by-nc-nd Journal of Global Antimicrobial Resistance 2020-05-06

Introduction: Tuberculosis (TB) is an ancient contagious disease, and continues to be the leading cause of morbidity mortality among infectious diseases.It can considered occupational disease when it happens in health professionals.These professionals are directly exposed TB a high risk population for latent tuberculosis infection (LTBI) active TB.The primary aim this study was estimate prevalence LTBI clinical administrative staff oncology referral hospital Rio Grande do Sul.The secondary...

10.4322/2357-9730.75447 article EN cc-by Clinical & Biomedical Research 2017-01-01
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