Anna Llort
A5085463132- Glioma Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Caveolin-1 and cellular processes
- Sarcoma Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Childhood Cancer Survivors' Quality of Life
- Biomarkers in Disease Mechanisms
- Acute Lymphoblastic Leukemia research
- Brain Metastases and Treatment
- RNA Research and Splicing
- Child and Adolescent Health
- Lipoproteins and Cardiovascular Health
- Cancer, Hypoxia, and Metabolism
- Neurofibromatosis and Schwannoma Cases
- CNS Lymphoma Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- Tumors and Oncological Cases
- Blood disorders and treatments
- Hematopoietic Stem Cell Transplantation
- Lymphoma Diagnosis and Treatment
- Polyomavirus and related diseases
- Histone Deacetylase Inhibitors Research
- Transplantation: Methods and Outcomes
- Immunodeficiency and Autoimmune Disorders
Vall d'Hebron Hospital Universitari
2011-2025
Vall d'Hebron Institut de Recerca
2017-2024
Comprehensive Blood & Cancer Center
2023
U-M Rogel Cancer Center
2023
Hospital Valle del Nalón
2017
Universitat Autònoma de Barcelona
2001-2014
Hospital Materno-Infantil
2011
Services Hospital
2010
Palmetto Hematology Oncology
2009
Abstract The molecular characterisation of medulloblastoma, the most common paediatric brain tumour, is crucial for correct management and treatment this heterogenous disease. However, insufficient tissue sample, presence tumour heterogeneity, or disseminated disease can challenge its diagnosis monitoring. Here, we report that cerebrospinal fluid (CSF) circulating DNA (ctDNA) recapitulates genomic alterations facilitates subgrouping risk stratification, providing valuable information about...
Abstract Tumors of the Ewing's sarcoma family (ESFT), such as (EWS) and primitive neuroectodermal tumors (PNET), are highly aggressive malignancies predominantly affecting children young adults. ESFT express chimeric transcription factors encoded by hybrid genes fusing EWS gene with several ETS genes, most commonly FLI-1. EWS/FLI-1 proteins responsible for malignant phenotype ESFT, but only few their transcriptional targets known. Using antisense short hairpin RNA–mediated expression...
Abstract The survival rates for children with cancer have increased appreciably over the last few decades; however, childhood survivors continue to suffer from long-lasting sequelae. Studies demonstrated that presence of malnutrition, over- and under-nutrition, at diagnosis or duration malnutrition during treatment is associated toxicity, infection, inferior survival. Dietary habits, along behavioral socioeconomic status, are known factors lead obesity undernutrition can affect prognosis...
<div>AbstractPurpose:<p>Tropomyosin receptor kinase (TRK) fusions are detected in less than 2% of central nervous system tumors. There limited data on the clinical course affected patients.</p>Experimental Design:<p>We conducted an international retrospective cohort study patients with TRK fusion–driven tumors.</p>Results:<p>A total 119 were identified. The median age at time diagnosis was 4.5 years. majority reported to have a histology consistent...
<p>Supplementary Figure S1. Diagram of population patients.</p>
<p>Supplementary Figure S2. A) Hazard ratio for progression or death according to clinical characteristics. B) LGG: Low-grade glioma, HGG: High-grade glioma</p>
<p>Supplementary Data S1. Definition of response, Description response criteria used by sites to evaluate tumor extend resection, resection sites.</p>
PTLD are the most frequent neoplasms in children postorgan transplantation. We describe our experience treatment of 14 (three with early and 11 late-onset disease) treated a step-wise protocol developed at institution. Treatment consisted reducing immunosuppressants, followed by rituximab chemotherapy if required. Rituximab, incorporated into 2001, has been determinant for total burden patients need to achieve remission. In seven who did not receive rituximab, anthracycline dose ranged from...
Abstract BACKGROUND Despite recent advances in our understanding of biology, pediatric patients diagnosed with diffuse intrinsic pontine glioma (DIPG) still face a bleak prognosis. In years, oncolytic adenovirus therapy has emerged as promising approach cancer treatment. METHODS We conducted phase Ib clinical trial newly DIPG, utilizing ALOCELYVIR, an advanced medicine that combines allogeneic mesenchymal stem cells carrying adenovirus. ALOCELYVIR was administered weekly intravenously...
We aim to describe the characteristics of patients with childhood-onset craniopharyngioma and analyze factors that impair quality life (QoL) in this population.
Abstract Purpose: TRK fusions are detected in less than 2% of central nervous system tumors. There limited data on the clinical course affected patients. Experimental design: We conducted an international retrospective cohort study patients with fusion-driven CNS Results: 119 were identified. The median age at time diagnosis was 4.5 years. majority reported to have a histology consistent high-grade glioma (HGG) (57.1%) followed by low-grade (LGG) (27.7%). Pediatric had better prognosis...