Nádia Silva

ORCID: 0000-0001-9881-4421
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About
Contact & Profiles
Research Areas
  • Aquaculture Nutrition and Growth
  • Reproductive biology and impacts on aquatic species
  • Physiological and biochemical adaptations
  • Thyroid Disorders and Treatments
  • Animal Behavior and Reproduction
  • Ultrasound Imaging and Elastography
  • Ultrasound and Hyperthermia Applications
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Avian ecology and behavior
  • Advanced Text Analysis Techniques
  • Congenital heart defects research
  • Sentiment Analysis and Opinion Mining
  • Developmental Biology and Gene Regulation
  • Microplastics and Plastic Pollution
  • Urinary Tract Infections Management
  • Dementia and Cognitive Impairment Research
  • Effects and risks of endocrine disrupting chemicals
  • 3D Printing in Biomedical Research
  • Bird parasitology and diseases
  • Pelvic floor disorders treatments
  • Parathyroid Disorders and Treatments
  • Muscle Physiology and Disorders
  • Oral and gingival health research
  • Pluripotent Stem Cells Research
  • Gut microbiota and health

University of Algarve
2010-2024

Algarve Biomedical Center
2023-2024

Hospital de São João
2021-2024

Instituto Politécnico de Beja
2024

Escola Superior de Saúde Egas Moniz
2023

Hospital Curry Cabral
2021

Universidade do Estado do Rio de Janeiro
2013-2020

Bandung Islamic University
2019

Universidade Federal de Goiás
2018

Laboratoire Evolution et Diversite Biologique
2009-2017

Abstract A bacterial cutinase from Thermobifida fusca , named Tfu_0883, was genetically modified by site‐directed mutagenesis to enhance its activity on poly(ethylene terephthalate) (PET). The new mutations tailored the catalytic site for PET, increasing affinity of this hydrophobic substrate and ability hydrolyze it. mutation I218A designed create space double Q132A/T101A both increase hydrophobicity. mutant soluble p ‐nitrophenyl butyrate increased two‐fold compared wild‐type cutinase,...

10.1002/biot.201000391 article EN Biotechnology Journal 2011-07-11

The presence of microplastics in the aquatic ecosystem represents a major issue for environment and human health. capacity organic pollutants to adsorb onto microplastic particles raises additional concerns, as it creates new route toxic compounds enter food web. Current knowledge on impact pristine and/or contaminated organisms remains insufficient, we provide here insights by evaluating their biological effects zebrafish (Danio rerio). Zebrafish larvae were raised ZEB316 stand-alone...

10.1016/j.chemosphere.2022.135198 article EN cc-by-nc Chemosphere 2022-06-02

A significant component of aquaculture is the production good quality larvae, and, in case flatfish, this tied up with change from a symmetric larva to an asymmetric juvenile. Despite pioneering work carried out on metamorphosis Japanese flounder (Paralichthys olivaceus) and summer dentatus), underlying molecular basis flatfish still relatively poorly characterized. It thyroid hormone (TH) driven process, role other hormones regulation process along interplay abiotic factors are...

10.1080/10641260802325377 article EN Reviews in Fisheries Science 2008-09-15

Vascular calcification (VC) is a frequent condition in chronic kidney disease (CKD) and well-established risk factor for the development of cardiovascular (CVD). Gut dysbiosis may contribute to CVD inflammation CKD patients. Nonetheless, role gut blood microbiomes CKD-associated VC remains unknown. Therefore, this pilot study aimed explore link between patients on peritoneal dialysis (CKD-PD). Our results showed relative changes specific taxa CKD-PD with without VC, namely Coprobacter,...

10.3390/biom12070867 article EN cc-by Biomolecules 2022-06-21

Abstract Flatfish metamorphosis is a unique post-embryonic developmental event in which thyroid hormones (THs) drive the development of symmetric pelagic larva into asymmetric benthic juveniles. One eyes migrates to join other eye on opposite side head. Developmental mechanisms at basis acquisition flatfish anatomical asymmetry remain an open question. Here we demonstrate that TH responsive centre, determined by deiodinase 2 expression, ventrally juxtaposed migrating sole ( Solea...

10.1038/s41598-018-29957-8 article EN cc-by Scientific Reports 2018-08-10

Covariation between melanin‐based colorations and other phenotypic attributes has been rarely measured simultaneously in males females. Such covariations mechanisms mediating them have crucial importance determining the signalling function of these coloured ornaments two sexes. We examined role four plumage patches as indicators quality both females sexually dimorphic dichromatic Eurasian kestrel Falco tinnunculus . Previous studies focused on size melanin either or individual quality. Here,...

10.1111/j.1600-048x.2010.05235.x article EN Journal of Avian Biology 2011-01-01

Abstract The process of eye migration in bilaterally symmetrical flatfish larvae starts with asymmetrical growth the dorsomedial parts ethmoid plate together frontal bones, structures initially found a position between eyes. movement these future ocular direction exerts stretch on fibroblasts connective tissue moving and that is to migrate. Secondarily, dense cell population ventral proliferate, possibly cued by pulling forces exerted eye. increased pushes dorsally. Osteoblasts are deposited...

10.1111/j.1469-7580.2006.00577.x article EN Journal of Anatomy 2006-06-23

The immune system has a crucial importance determining animal health and survival. Its maintenance activation are costly usually trade with other physiologically functions. In birds, number size of siblings in nest likely to determine the development immunity. Indeed lower immunocompetence is expected large than small broods. Moreover, asynchronous breeders, differ because asynchrony produces marked hierarchy within‐broods. Here we studied effect environmental conditions at nest, chick sex...

10.1111/j.2007.0908-8857.04081.x article EN Journal of Avian Biology 2007-10-23

Abstract Background Flatfish metamorphosis is a thyroid hormone (TH) driven process which leads to dramatic change from symmetrical larva an asymmetrical juvenile. The effect of THs on muscle and in particular sarcomer protein genes largely unexplored fish. Troponin T ( TnT ), pivotal the assembly skeletal muscles sarcomeres modulator calcium contraction, during flatfish metamophosis studied. Results In present study five cDNAs for halibut were cloned; three splice variants arising single...

10.1186/1471-213x-7-71 article EN cc-by BMC Developmental Biology 2007-06-18

Ultrasound contrast imaging has been used to assess tumour growth and regression by assessing the flow through macro- micro-vasculature. Our aim was differentiate blood kinetics of vessels such as veins, arteries microvasculature within limits spatial resolution contrast-enhanced ultrasound imaging. The highly vascularised ovine ovary a biological model. Perfusion with SonoVue recorded Philips iU22 scanner in mode. One ewe treated prostaglandin induce vascular regression. Time-intensity...

10.1016/j.ultrasmedbio.2019.05.015 article EN cc-by Ultrasound in Medicine & Biology 2019-06-15
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