A5051455775- Prenatal Screening and Diagnostics
- Congenital Diaphragmatic Hernia Studies
- Congenital Anomalies and Fetal Surgery
- Urological Disorders and Treatments
- Pregnancy and preeclampsia studies
- Pediatric Urology and Nephrology Studies
- Neonatal Respiratory Health Research
- Fetal and Pediatric Neurological Disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Ultrasound in Clinical Applications
- Craniofacial Disorders and Treatments
- Congenital Heart Disease Studies
- Cleft Lip and Palate Research
- Esophageal and GI Pathology
- Birth, Development, and Health
- Genomic variations and chromosomal abnormalities
- Gestational Diabetes Research and Management
- Tracheal and airway disorders
- Hernia repair and management
- Intestinal Malrotation and Obstruction Disorders
- Renal and related cancers
- Maternal and fetal healthcare
- Renal and Vascular Pathologies
- Pediatric Hepatobiliary Diseases and Treatments
- Ureteral procedures and complications
Erasmus MC - Sophia Children’s Hospital
1993-2025
Erasmus MC
2014-2024
Erasmus University Rotterdam
2010-2022
Rotterdam University of Applied Sciences
1990-2019
John Wiley & Sons (United Kingdom)
2019
Hudson Institute
2019
Beijing Obstetrics and Gynecology Hospital
2010
King's College Hospital
1983-1988
King's College School
1987
Royal Sussex County Hospital
1987
In 82 consecutive cases of intrauterine growth retardation managed by established criteria fetal Doppler studies identified 29 fetuses with absence end diastolic frequencies in the aorta. These same were significantly more retarded (p less than 0.001) and had an earlier gestational age at delivery those present. A subgroup these was analysed detail to examine prognostic value this phenomenon for neonate. Two groups neonates equivalent a birth weight below 2000 g compared. There 26 absent...
OBJECTIVE: Genetic analyses in humans suggest a role for retinoid-related genes the pathogenesis of congenital diaphragmatic hernia (CDH). The goal this study was to investigate vitamin A status mothers and their newborns association with CDH. METHODS: We conducted hospital-based, case-control 22 case 34 control newborns. In maternal cord blood samples, retinol retinol-binding protein (RBP) levels were measured high-performance liquid chromatography an enzyme-linked immunosorbent assay,...
ABSTRACT Objective Fetal megacystis presents a challenge in terms of counseling and management because its varied etiology evolution. The aim this study was to present comprehensive overview the underlying etiologies structural anomalies associated with fetal megacystis. Methods This retrospective multicenter cases referred medicine unit one eight academic hospitals Netherlands diagnosis For each case, data on measurements urinary tract were collected. All available postmortem examinations...
To assess the predictive value of observed-to-expected lung-to-head ratio (O/E LHR) for survival and chronic lung disease (CLD) in survivors left-sided congenital diaphragmatic hernia (CDH) an era standardized neonatal treatment, to evaluate O/E LHR trajectory survival. This retrospective cohort study was performed two high-volume CDH centers Netherlands prenatally detected, isolated patients born between 2008 2014. liver position were determined using 2D-ultrasonography at three time points...
Summary. Variation in indices used to characterize the maximum frequency outline of waveforms obtained from uteroplacental and fetal circulations by duplex Doppler ultrasound was studied between observers, over a 24‐h period before after meal. No significant differences were found. Reference ranges derived for three indices, A/B ratio, resistance index pulsatility index, descending aorta, umbilical artery, placental maternal sides circulation. Indices circulation demonstrated fall 16 24...
CAMPBELL, S.; GRIFFIN, D. R.; PEARCE, J. M.; DIAZ-RECASENS, J.; COHEN-OVERBEEK, T. E.; WILLSON, K.; TEAGUE, M. Author Information
We have investigated whether replacing conventional karyotyping by SNP array analysis in cases of foetal ultrasound abnormalities would increase the diagnostic yield and speed prenatal diagnosis clinical practice. From May 2009 till June 2011 we performed HumanCytoSNP-12 (HCS) ( http://www.Illumina.com ) 207 structural abnormalities. HCS allows detecting unbalanced genomic with a resolution about 150/200 kb. All were selected geneticist after excluding most common aneuploidies RAD (rapid...
ABSTRACT Objective To propose a staging system for congenital lower urinary tract obstruction (LUTO) capable of predicting the severity condition and its prognosis. Methods This was national retrospective study carried out at eight Academic Hospitals in The Netherlands. We collected prenatal postnatal data fetuses high risk isolated LUTO that were managed conservatively. Postnatal renal function assessed by estimated glomerular filtration rate (eGFR), calculated using Schwartz formula,...
Objective. Our objective was to investigate the outcome of neonates with idiopathic polyhydramnios in first year after birth.Methods. All patients diagnosed Erasmus Medical Centre Rotterdam and University Utrecht between January 2000 April 2005 were studied. The variables included mode delivery, pre-term birth weight, macrosomia, large-for-gestational-age (weight > p90), neonatal or infant mortality morbidity at 1 delivery. These related antenatal findings, including onset ultrasonographic...
Clinical symptoms and ultrasound signs during pregnancy could suggest the presence of esophageal atresia (EA). However, most often EA is diagnosed postnatally. The aim our study to evaluate course outcome for prenatally postnatally EA. In addition, we studied isolated versus nonisolated EA.In a retrospective data analysis, characteristics, maternal neonatal variables as well clinical were compared fetuses/neonates with prenatal (n = 30) or postnatal 49) diagnosis in terms morbidity mortality...
To investigate the natural history of fetal megacystis from diagnosis in utero to postnatal outcome, and identify prognostic indicators spontaneous resolution outcome after resolution.This was a national retrospective cohort study. Fetal defined first trimester as longitudinal bladder diameter (LBD) ≥ 7 mm, second third trimesters an enlarged failing empty during entire extended ultrasound examination. LBD gestational age (GA) at were investigated with respect likelihood respectively....
ABSTRACT Objective To propose a clinical score for the optimal antenatal diagnosis of fetal lower urinary tract obstruction (LUTO) in second and third trimesters pregnancy, as an alternative to commonly used ultrasound triad megacystis, keyhole sign hydronephrosis. Methods This was national retrospective study carried out at eight tertiary medicine units (FMUs) The Netherlands. Only cases referred megacystis from trimester onwards with clear postnatal were included study. At referral, data...
To analyze comprehensively the incidence, antenatal ultrasound characteristics and prognostic implications of pop-off mechanisms fetal urinary system in pregnancies with suspected megacystis. This was a retrospective multicenter study megacystis conducted across all academic hospitals The Netherlands. Three were identified: presence an umbilical cord cyst (UCC), extravasation urine into intraperitoneal space (ascites) or perirenal subcapsular (urinoma), megaureter/ureterocele. Cases that...
To determine whether first and late second trimester serum total high density lipoprotein cholesterol are associated with blood pressure, uterine artery pulsatility index pregnancy outcome.A prospective cohort study. Data were analysed using multiple linear logistic regression analysis.Three hundred ninety-three pregnant women requesting chorionic villus sampling because of advanced maternal age (36 years older).Serum measured by an automated enzymatic method. Uterine flow velocity waveforms...
Abstract The objective of this paper was to determine whether first‐and second‐trimester uterine artery Doppler velocimetry are associated with pregnancy complications in women advanced maternal age. A prospective cohort study 352 aged 35 years and older studied. pulsatility index (PI) values at 12–13 weeks gestation were significantly development hypertensive disorders, a small‐for‐gestational‐age infant gestational diabetes, relative risk exceeding 4, 2 8, respectively for PI the highest...
To determine the degree of compensatory enlargement, and its time onset, solitary functioning kidney (SFK) in fetuses with unilateral renal agenesis (URA) or multicystic dysplasia (MCKD).This was a retrospective study URA MCKD diagnosed prenatally confirmed postnatally period from January 1999 to May 2011. Fetuses any other congenital anomalies were excluded. Measurements length retrieved our prenatal ultrasound database nomogram established compared that for normal length.In total, 67...