A5051076073- Acute Myeloid Leukemia Research
- Blood groups and transfusion
- Complement system in diseases
- Platelet Disorders and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Erythrocyte Function and Pathophysiology
- Pneumonia and Respiratory Infections
- Immunodeficiency and Autoimmune Disorders
- Blood disorders and treatments
- Nuclear Receptors and Signaling
- Neonatal Health and Biochemistry
- Liver Disease and Transplantation
- Multiple Myeloma Research and Treatments
- Viral gastroenteritis research and epidemiology
- Botulinum Toxin and Related Neurological Disorders
- Microscopic Colitis
- Hematopoietic Stem Cell Transplantation
- Ubiquitin and proteasome pathways
- Electric Motor Design and Analysis
- Quinazolinone synthesis and applications
- Peptidase Inhibition and Analysis
- Digital Imaging for Blood Diseases
- Williams Syndrome Research
- Protein Tyrosine Phosphatases
- Single-cell and spatial transcriptomics
Nihon University
2019-2023
Waseda University
2023
Nihon University Itabashi Hospital
2019-2021
Tokyo Metropolitan Bokutoh Hospital
2020
Kyorin University
1975
Treatment of children with refractory immune thrombocytopenic purpura (ITP) is challenging and poorly established. We retrospectively reviewed the clinical data 87 patients under age 16 years who were diagnosed ITP from April 1998 to March 2017 in our institution. Refractory was defined as a platelet count < 50 × 109/L at 14 days after receiving intravenous immunoglobulin (IVIG) prednisolone. presumed that there pathophysiological overlap between thrombocytopenia (RT): subtype cytopenia...
Background: The treatment of refractory immune thrombocytopenic purpura (ITP) in children is challenging. Although various medical approaches have been used to treat ITP, few data are available on the long‐term incidence outcomes with ITP. Aims: In this study, we aimed reveal 87 ITP our institution during last 19 years. Methods: We retrospectively reviewed clinical who were newly diagnosed from April 1998 March 2017 at Nihon University Itabashi Hospital. Patients aged below 16 years included...
73 歳の男性.M 蛋白を認め当院に紹介となり, IgG-κ 型骨髄腫 (D&S stage IIA, ISS I) と診断した. 経過観察していたが,IgG が 6,715 mg/dl に増加したた め bortezomib を週 1 回,1.3 mg/m2 の経静脈投与で開始 した.6 回の投与翌日に嘔吐がみられ,麻痺性イレウス と診断し,以後の を中止した.Vincristine, thalidomide などの前治療歴のある症例や を 週 2 回投与した症例で によるイレウスが報 告されている.本症例のように初回治療例で,週 回の 投与でもイレウスに注意する必要がある.
"Haploidentical bone marrow transplantation in a child with fatal hepatic failure due to graft-versus-host disease after cord blood transplantation." Leukemia & Lymphoma, 61(5), pp. 1263–1264
A 17-year-old woman was admitted to our hospital because of abdominal pain, diarrhea and anal bleeding. Emergent colonoscopy revealed severe hemorrhagic colitis extending from the rectum through descending colon. The most remarkable findings were inflammation, edema ulcers on sigmoid colon, which similar ischemic colitis. total could not be performed stenosis Hemorrhagic Escerichia coli O-157 cultured in stool. Colonoscopic 9th day showed sporadic, spotty or short longitudinal ulcers. On...
炎天下の過激な運動により,重篤な肝障害と横紋筋融解をきたした日射病の1症例を経験したので報告する.症例は17歳男子学生.炎天下のサッカー練習中に突然意識が消失し近医に入院した.体温40°Cで錯乱状態であった.翌日には意識は改善したが,黄疸,肝機能異常が認められ当院に転院した.入院時,黄疸(+),肝を右肋骨弓下に1横指触知した.総ビリルビン4.5mg/dl, GOT4, 224mIU, GPT 5, 190mIU, PT 30%,尿ミオグロビン(+),CPK 4,920mIU, CPKアイソザイムMM型98%,HBマーカー(-),HA抗体(-)であった.入院後,肝機能は順調に回復し第16病日にはほぼ正常化した.第25病日の肝生検では,肝細胞索の乱れ,細胞の大小不同,二核細胞を認めたが,細胞浸潤はほとんどみられなかった.日射病における肝障害の発生機序については高体温,肝循環障害,低酸素血症等が考えられているがまだ解明されていない.