- Laser-Plasma Interactions and Diagnostics
- Plasma Diagnostics and Applications
- Particle accelerators and beam dynamics
- Gyrotron and Vacuum Electronics Research
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Pulsed Power Technology Applications
- Gastrointestinal Tumor Research and Treatment
- Magnetic confinement fusion research
- Laser-Matter Interactions and Applications
- Metal and Thin Film Mechanics
- Ion-surface interactions and analysis
- Elevator Systems and Control
- Metastasis and carcinoma case studies
- Laser-induced spectroscopy and plasma
- Esophageal Cancer Research and Treatment
- Vibration and Dynamic Analysis
- Colorectal Cancer Screening and Detection
- Gastroesophageal reflux and treatments
- Dust and Plasma Wave Phenomena
- Gastrointestinal disorders and treatments
- Laser Design and Applications
- Genetic factors in colorectal cancer
- Eosinophilic Esophagitis
- Electrostatic Discharge in Electronics
Kameda Medical Center
2024-2025
Kyoto University
2003-2025
Mie University
2025
Kyoto University Hospital
2023-2024
Gifu Prefectural Tajimi Hospital
2000-2024
McGill University Health Centre
2024
NTT (Japan)
2020-2024
Showa University Koto Toyosu Hospital
2016-2023
Hamamatsu University School of Medicine
2021-2023
Kōchi University
2012-2023
Malnutrition in the early stage has been reported as an independent predictor of survival amyotrophic lateral sclerosis (ALS). We analyzed retrospectively effect variation body mass index (BMI) on ALS patients. In total, 77 consecutive patients were enrolled from nine hospitals Japan. Reduction rate BMI was calculated before disease onset and at time first visit to each hospital. correlation between reduction total duration. Results showed that median 2.5 per year (interquartile range...
A proof-of-principle experiment demonstrates the generation of radiation from Cherenkov wake excited by an ultrashort- and ultrahigh-power pulse laser in a perpendicularly magnetized plasma. The frequency is millimeter range (up to 200 GHz). intensity proportional magnetic field as expected theory. Polarization emitted also detected. difference between these experiments previous theory can be explained electrons' oscillation electric narrow column ions focal region.
We retrospectively investigated the efficacy and feasibility of concurrent chemoradiotherapy for patients with severe dysphagia caused by oesophageal squamous cell carcinoma. Concurrent was performed in 57 T3 or T4 disease containing M1 lymph node (LYM) disease. Chemotherapy consisted protracted infusion 5-fluorouracil (5-FU) 400 mg m(-2) 24 h(-1) on days 1-5 8-12, combined 2-h cisplatin (CDDP) 40 1 8. Radiation treatment at a dose 30 Gy 15 fractions mediastinum administered concomitantly...
Abstract With the incorporation of immune checkpoint inhibitors into treatment endometrial cancer (EC), a deeper understanding tumor microenvironment is critical. Tertiary lymphoid structures (TLSs) are considered favorable prognostic factors for EC, but significance their spatial distribution remains unclear. B cell receptor repertoire analysis performed using six TLS samples located at various distances from showed that TLSs in distal areas had more shared clones with tumor-infiltrating...
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-dependent food allergy that causes vomiting, extreme lethargy, marked pallor, diarrhoea and hypotension following ingestion of allergens [1, 2]. Although cytometric transcriptome analysis peripheral blood after the onset symptoms in patients with FPIES has revealed activation systemic innate immune responses [3, 4], few studies have explored these at earlier time points. Therefore, this study, we aimed to elucidate pathogenic...
Abstract The adap1 (ADP‐ribosylation factor GTPase‐activating protein [ArfGAP] with dual pleckstrin homology [PH] domains 1) gene is predominantly expressed in the mouse brain and important neural differentiation development. However, functions of morphogenesis, locomotor activity, behaviors vertebrates are not fully understood. Whole‐mount situ hybridization (WISH) analysis revealed that was widely zebrafish brain, including forebrain, midbrain, hindbrain, during early embryogenesis. To...
Abstract Purpose: The purpose is to compare the molecular characteristics of serrated adenomas (SAs) with those conventional (CADs) and hyperplastic polyps (HPs). Experimental Design: We evaluated proliferative activity alterations in 47 SAs (25 pure-type 22 mixed-type), 71 CADs, 23 HPs. Results: SAs, as by Ki-67 expression, was intermediate between CADs There no significant difference incidence KRAS or p53 mutations three histological groups. In microsatellite instability (MSI) analysis,...
Observations of the polar region Sun are critically important for understanding solar dynamo and acceleration wind. We carried out precise magnetic observations on both North quiet at East limb with Spectro-Polarimeter Solar Optical Telescope aboard Hinode to characterize respect Sun. The average area total flux kG concentrations in appear be larger than those field vectors classified as vertical have symmetric histograms around zero strengths, showing balanced positive negative flux, while...
Objectives The clinical success of per‐oral endoscopic myotomy ( POEM ) has led to the development a new field ‘submucosal endoscopy’. This study aimed evaluate safety, efficacy, and limitations tumor resection POET in management submucosal tumors SMT s) esophagus gastric cardia. Methods was performed 47 patients from January 2011 December 2017. indication for s ≤ 30 mm minor axis diameter. Patient characteristics (age, gender, location, size, histology), operative results (procedure time...
Being able to control the acoustic events (AEs) which we want listen would allow development of more controllable hearable devices.This paper addresses AE sound selection (or removal) problems, that define as extraction suppression) all sounds belong one or multiple desired classes.Although this problem could be addressed with a combination source separation followed by classification, is sub-optimal way solving problem.Moreover, usually requires knowing maximum number sources, may not...
The interaction of free electrons with intense laser beams in vacuum is studied using a three-dimensional test particle simulation model that solves the relativistic Newton–Lorentz equations motion analytically specified fields. Recently, group solutions was found for very fields show interesting and unusual characteristics. In particular, it an electron can be captured within high-intensity region, rather than expelled from it, accelerated to GeV energies acceleration gradients on order...
Using a gas-jet flow, via the interaction between an ultrashort high-intensity laser pulse and plasma in presence of perpendicular external dc magnetic field, short radiation from magnetized wakefield has been observed. Different nozzles are used order to generate different densities gas profiles. The neutral density flow measured with Mach-Zehnder interferometer is found be proportional back pressure jet range 1 8 atm. Strength applied field varies 0 kG at region. frequency emitted width...
Germline point or small frameshift mutations of the CDH1 (E-cadherin) gene are known to cause familial gastric cancer (FGC), but frequency is low in Japanese patients with FGC. Because recent studies have reported germline large genomic deletions European and Canadian FGC, present study we examined DNA samples from 13 FGC determine whether similar changes were this population. Using a sequencing analysis, 1-bp deletion (c.1212delC), leading production truncated protein (p.Asn405IlefsX12),...
High power testing methods for HV DC circuit breaker (DCCB) were investigated. Short breaking tests using quasi-DC current performed DCCB based on the oscillation scheme with active injection. This has a high voltage vacuum as interrupter unit. The two kinds of method (power frequency peak and charged reactor method) which have different waveforms. Interruption performance evaluated results obtained from each method. In results, interruption these was same. Moreover, effect saturable...
This case documents a seldom-described event of retained products conception masquerading as an acquired arteriovenous malformation (AVM) the uterus. The patient presented with sudden onset heavy vaginal bleeding 6 weeks after artificial abortion. Ultrasonography and magnetic resonance imaging revealed diffuse intramural lesion predominantly consisting prominent vessels, which raised suspicion AVM. Hysterectomy placenta that were necrotic encroached into thin myometrium.
Magnifying chromoendoscopy is an exciting new tool and offers detailed analysis of the morphological architecture mucosal crypt orifices. In this review, we principally show efficacy magnifying for differential diagnosis colorectal lesions such as prediction between non‐neoplastic neoplastic ones, distinction endoscopically treatable early invasive cancers untreatable based on a review literature our experience at two National Cancer Centers in Japan. Overall diagnostic accuracy by...
The identification of circulating tumour cells (CTCs) in peripheral blood is a useful approach to estimate prognosis, monitor disease progression, and measure treatment effects various malignancies. However, clinical relevance CTCs controversial. We attempted detect viable the gastric cancer patients using telomerase-specific viral agent. took 7.5-ml sample from 65 treatment-negative before surgery 10 healthy volunteers. detected samples after incubating them with telomerase-specific,...