Liu Bao-chen

ORCID: 0000-0002-0067-3497
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About
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Research Areas
  • Civil and Geotechnical Engineering Research
  • Geoscience and Mining Technology
  • Geomechanics and Mining Engineering
  • Landslides and related hazards
  • Grouting, Rheology, and Soil Mechanics
  • Blasting Impact and Analysis
  • Soil, Finite Element Methods
  • Geotechnical Engineering and Analysis
  • Geotechnical Engineering and Soil Stabilization
  • Advanced Decision-Making Techniques
  • Geotechnical Engineering and Underground Structures
  • Polymer crystallization and properties
  • Abdominal vascular conditions and treatments
  • Evaluation and Optimization Models
  • Polymer Foaming and Composites
  • Liver Disease and Transplantation
  • Dam Engineering and Safety
  • Injection Molding Process and Properties
  • biodegradable polymer synthesis and properties
  • Vascular anomalies and interventions
  • Rock Mechanics and Modeling
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Geotechnical Engineering and Soil Mechanics
  • Railway Engineering and Dynamics
  • Evaluation Methods in Various Fields

Guilin University of Electronic Technology
2018-2024

Shanghai Electric (China)
2024

Qingdao University
2024

Shandong Jianzhu University
2024

China Academy of Railway Sciences
2024

Zhengzhou University
2008-2023

Nanjing University
2013-2023

Nanjing General Hospital of Nanjing Military Command
2014-2023

Guilin University of Technology
2006-2021

Central South University
2006-2018

Microvascular endothelial damage caused by intestinal ischemia‒reperfusion (II/R) is a primary catalyst for microcirculation dysfunction and enterogenous infection. Previous studies have mainly focused on how neutrophil extracellular traps (NETs) ferroptosis cause epithelial injury, little attention has been given to NETs, from circulatory neutrophils, affect cells during II/R. This study aimed unravel the mechanisms through which NETs microvascular dysfunction. We first detected heightened...

10.1016/j.redox.2023.102906 article EN cc-by-nc-nd Redox Biology 2023-10-04

Background: Hesperetin (HES), one of the major flavonoids that has various biological activities, such as anti-inflammatory and antioxidant may preserve intestinal barrier during sepsis. However, detailed mechanism remains unclear. Our previous studies confirmed neutrophil extracellular traps (NETs) jeopardize via a reactive oxygen species (ROS)-dependent pathway Therefore, we hypothesized HES inhibit NET formation protect function Methods: Mice were pretreated with (50 mg kg-1)...

10.1039/d2fo02707k article EN Food & Function 2023-01-01

A soil–rock mixture consists of soil and broken rocks mixed proportionally, it has more complicated seepage characteristics than pure or rocks. Current research on the mixtures is still limited to empirical equations. This paper presents an improved theoretical compound model for permeability coefficient relative concentrations individual constituents (i.e., rocks). considers gap filled by particle grains in a under same compaction level, as well reduced porosity decreased caused fine...

10.1061/(asce)gm.1943-5622.0000768 article EN International Journal of Geomechanics 2016-09-20

A growing number of studies have recently revealed a potential role for neutrophil extracellular traps (NETs) in the development inflammation, coagulation and cell death. Deleterious consequences NETs been identified ischemia-reperfusion (I/R)-induced organ damage, thrombosis sepsis. And exogenous DNase-I has suggested as therapeutic strategy to attenuate (I/R) injuries kidney, brain myocardium. Herein, we designed study investigate whether contribute pathogenesis intestinal I/R injury...

10.1038/s41598-018-36198-2 article EN cc-by Scientific Reports 2018-12-06

Soil–rock mixture is a typical discontinuous material and often used as roadbed filler. Rock content key factor in this mixture's properties. The damage pattern of soil–rock mixtures with different rock contents after freeze–thaw cycles more complicated than that normal state. behaviour analysed study. Firstly, size-distributed subgrade coarse grained soil samples (35, 45, 55 65%) are prepared. subjected to periodically (24 h per cycle) for times (0 10). Large-scale indoor triaxial tests...

10.1080/10298436.2018.1435879 article EN International Journal of Pavement Engineering 2018-02-23

Abstract Neutrophil extracellular trap (NET) has been confirmed to be related gut barrier injury during intestinal ischaemia–reperfusion (II/R). However, the specific molecular regulatory mechanism of NETs in II/R‐induced damage yet fully elucidated. Here, we reported increased infiltration accompanied by elevated inflammatory cytokines, cellular necroptosis and tight junction disruption intestine human II/R patients. Meanwhile, aggravated Caco‐2 epithelial cell necroptosis, impairing...

10.1111/cpr.13538 article EN cc-by Cell Proliferation 2023-09-10

Taking the red clay from Guilin, China as object, this paper prepares samples with different initial water contents, extracts crack parameters images on under cyclic drying and wetting through image processing, analyzes laws of development. In addition, parallel were subject to shrinkage tests direct shear same wetting. Based test results, authors discussed deformaiton strength change for wetting, examined relationship between cracking, properties, detiroation clay. The results show that:...

10.1016/j.aej.2021.08.011 article EN cc-by-nc-nd Alexandria Engineering Journal 2021-08-14

During the excavation of large-scale underground caverns, in which dynamic feedback analysis is required, efficiency and accuracy determining mechanical parameters surrounding rock masses have significant influences on safety effectiveness construction. In this study, a novel intelligent displacement back-analysis method proposed to determine geomechanical parameters. method, parameter determination transformed into global optimization problem, treats error between situ measured...

10.1061/(asce)gm.1943-5622.0001657 article EN International Journal of Geomechanics 2020-03-12

Background: Acute mesenteric ischemia (AMI) is a rare life-threatening condition, especially for the patients with transmural intestinal necrosis (TIN). However, optimal time surgical intervention controversial. As series study, this study aimed to identify outcomes and clinical characteristic of TIN.Methods: Clinical data 158 AMI from January 2010 December 2017 were retrospectively analyzed in national gastrointestinal referral center China confirm predictors TIN.Results: According results...

10.1080/00365521.2019.1646800 article EN Scandinavian Journal of Gastroenterology 2019-07-30

Morphological variations of lamellae isotactic polypropylene (iPP) grown in thin films have been examined experimentally by optical microscopy (OM), atomic force (AFM), and transmission electron (TEM). A flower-shaped morphology iPP crystals, composed several petal-like radiating from a nucleus, was typically found. At crystallization temperatures (Tc) below 135 °C, initially with flat α-iPP backbone many regular branches were formed, which able to induce epitaxial nucleation γ-iPP,...

10.1021/acs.macromol.7b01381 article EN Macromolecules 2017-08-04

Injection processing parameters directly influence the final fiber length and may have a negative effect on mechanical properties of part. The aim work is to investigate quantify effects injection rate (2/10/50 cm 3 /s) length, distribution, orientation during molding long‐glass‐fiber‐reinforced polypropylene (LGF/PP) by experimental simulated methods. When increases from 2 10 /s, sharply decreases original 11 mm 3.43 at nozzle 1.30 filling end, almost 88% fibers are less than when 50 /s. A...

10.1002/pen.25254 article EN Polymer Engineering and Science 2019-11-01

Abstract The nucleated isotactic polypropylene (iPP) was molded by water‐assisted injection molding. crystalline morphology and orientation distribution were studied. results show that shear brought melt filling pressurized water penetration can separately induce the formation of oriented structures in skin region (i.e., near mold cavity wall) channel region. For virgin iPP, slightly lamellae appear exclusively above aforementioned regions. However, shish‐kebab structure occurs not only iPP...

10.1002/pen.22095 article EN Polymer Engineering and Science 2012-02-17

Abstract High density polyethylene (HDPE) was molded by a new polymer processing method, that is, water‐assisted injection molding (WAIM), and its hierarchical structure studied two‐dimensional small angle X‐ray scattering (SAXS). For comparison, the of HDPE conventional (CIM) also characterized. The result shows WAIM part exhibits distinct skin‐core‐water channel which is different from skin‐core for CIM part. In skin layer both parts, shish‐kebab formed due to shear stress brought melt...

10.1002/app.36408 article EN Journal of Applied Polymer Science 2012-01-22
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