A5068439544- Edible Oils Quality and Analysis
- Analytical Chemistry and Chromatography
- Metabolomics and Mass Spectrometry Studies
- Antibiotics Pharmacokinetics and Efficacy
- Saffron Plant Research Studies
- Cholesterol and Lipid Metabolism
- Antimicrobial Resistance in Staphylococcus
- Spectroscopy and Chemometric Analyses
- Phytochemistry and Biological Activities
- Analytical Methods in Pharmaceuticals
- Pharmaceutical and Antibiotic Environmental Impacts
- Essential Oils and Antimicrobial Activity
- Flavonoids in Medical Research
- Fatty Acid Research and Health
- Pneumonia and Respiratory Infections
- Pesticide and Herbicide Environmental Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Phytochemicals and Antioxidant Activities
- Antibiotic Resistance in Bacteria
- Pesticide Residue Analysis and Safety
- Mitochondrial Function and Pathology
- Natural product bioactivities and synthesis
- Mass Spectrometry Techniques and Applications
- Advanced Chemical Sensor Technologies
- Birth, Development, and Health
National and Kapodistrian University of Athens
2016-2025
Hippocration General Hospital
2023
Goulandris Natural History Museum
2004-2021
University of Patras
2004-2007
Aristotle University of Thessaloniki
2007
American Museum of Natural History
2003
The high polyphenol content of the wastewater is major environmental problem caused by olive mills. A pilot scale system for treatment oil mills was developed aiming at recovery added value-contained polyphenols and reduction problems. consists three main successive sections: first one includes filtration stages gradual suspended solids up to a limit 25 μm. second section passing filtered through series adsorbent resins (XAD16 XAD7HP) in order achieve deodoring decolorization removal/...
The aim of the current study was qualitative exploration and quantitative monitoring key olive secondary metabolites in different production steps (drupes, paste, first final oil) throughout a virgin oil line. Greek variety Koroneiki selected as one most representative olives, which is rich biological active compounds. For time, an HPLC-Orbitrap platform employed for both purposes. Fifty-two components belonging to phenyl alcohols, secoiridoids, flavonoids, triterpenes, lactones were...
The chemical compositions of the essential oils obtained from aerial parts five taxa Sideritis were analyzed using various GC-MS techniques. A total 99 different compounds was identified, and significant differences (qualitative quantitative) observed between samples. in vitro antimicrobial activity against six bacteria three fungi is also reported.
The content of polyphenols in table olives is highly influenced by the olive variety and debittering process applied on fruits. Nine commercial types Greek were examined for their oleuropein hydroxytyrosol. A very simple extraction procedure a chromatographic methodology simultaneous quantitation (OE) hydroxytyrosol (HT) drupes, using boiling water followed direct HPLC analysis. Hydroxytyrosol was found all that studied. Kalamata Green "tsakistes" Megaritiki contained highest quantity...
Vaccination is currently the most effective strategy for mitigation of COVID-19 pandemic. mRNA vaccines trigger immune system to produce neutralizing antibodies (NAbs) against SARS-CoV-2 spike proteins. However, underlying molecular processes affecting response after vaccination remain poorly understood, while there significant heterogeneity in among individuals. Metabolomics have often been used provide a deeper understanding cell responses, but context such data are scarce. Mass...
ABSTRACT Early life stress exposure exerts detrimental effects in adulthood and is a risk factor for psychiatric disorders. Studies addressing the molecular mechanisms of early have primarily focused on hormones circuits. However, little known how mitochondria mitochondrial dynamics (i.e., orchestration fission, fusion, mitophagy, biogenesis) modulate responses. Here, we used maternal separation with weaning (MSEW) paradigm to investigate behavioral stress‐elicited male female C57BL/6 mice...
Anxiety and stress-related disorders affect all ages in geographical areas. As high anxiety chronic stress result the modulation of mitochondrial pathways, intensive research is being carried out on pharmaceutical interventions that alleviate pertinent symptomatology. Therefore, innovative approaches currently pursued include substances target mitochondria bearing an antioxidant moiety. In this study, a newly synthesized consisting triphenylphosphine (TPP), six-carbon alkyl spacer,...
Abstract This study demonstrates a simple method for one‐step isolation of the main secondary metabolites hydroalcoholic extract Crocus sativus stigmas (saffron) using step‐gradient centrifugal partition chromatography. The analysis was performed in dual and elution−extrusion mode, five biphasic systems solvents heptane/ethyl acetate/butanol/ethanol/water ratios 4:10:0:4:10, 1:13:0:4:10, 1:12:1:4:10, 1:10:3:4:10, 1:7:6:4:10. Five major crocins, picrocrocin, crocetin were directly isolated...
This work deals with the design, synthesis, and evaluation of cardioprotective properties a number novel hybrid compounds combining adenine nucleus suitable H2S slow-releasing moiety, coupled via stable ether bond. The release rate hybrids their ability to increase cGMP were estimated in vitro. most promising derivatives 4 11, both containing 4-hydroxythiobenzamide moiety as donor, selected for further vivo evaluation. Their was recorded using new fully validated UPLC-DAD method. Both...
A method based on liquid chromatography-tandem mass spectrometry was developed and validated for the qualitative quantitative detection of chloramphenicol (CAP) in seafood samples. The analysis CAP residues is important because can cause serious acute reactions humans, including aplastic anemia leukemia. proposed methodology includes a cleanup solid-phase extraction procedure with high recovery efficiency (>90%). Chromatographic separation internal standard (IS) carried out C(18) column,...
Abstract Oleuropein (OE) is the cardinal bioactive compound derived from Olea europaea and possesses numerous beneficial properties for human health. However, despite plethora of analytical methods that have studied biological fate olive oil‐derived compounds, no validated methodology has been published to date simultaneous determination OE, along with all its major metabolites. In this study, a liquid chromatography‐electrospray ionization‐tandem mass spectrometry (LC‐ESI MS/MS) method...