A5033693721- Renal Transplantation Outcomes and Treatments
- Testicular diseases and treatments
- Metabolism and Genetic Disorders
- Pulmonary Hypertension Research and Treatments
- Neutropenia and Cancer Infections
- Gastrointestinal Bleeding Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Multiple Myeloma Research and Treatments
- Mycobacterium research and diagnosis
- Heme Oxygenase-1 and Carbon Monoxide
- Colorectal and Anal Carcinomas
- Respiratory Support and Mechanisms
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Vascular Malformations and Hemangiomas
- Neonatal Respiratory Health Research
- Autoimmune Bullous Skin Diseases
- Dysphagia Assessment and Management
- Drug-Induced Adverse Reactions
- Congenital Diaphragmatic Hernia Studies
- Antifungal resistance and susceptibility
- Oral health in cancer treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Urologic and reproductive health conditions
- Neonatal and Maternal Infections
- Legionella and Acanthamoeba research
Inje University Haeundae Paik Hospital
2014-2024
Catholic University of Korea
2020-2021
Seoul St. Mary's Hospital
2021
Seoul National University
2019
Inje University
2015
Hypochlorous acid (HOCl) is generated in the immune system to kill microorganisms. In Escherichia coli , a hypochlorite-specific transcription regulator, HypT, has been characterized. HypT belongs LysR-type transcriptional regulator (LTTR) family that contains DNA-binding domain (DBD) and regulatory (RD). Here, we identified hypT gene from Salmonella enterica serovar Typhimurium determined crystal structures of full-length protein RD. The structure reveals type tetrameric assembly LTTR...
Teratoma of mediastinum is rare germ cell tumor. Anterior the most common extragonadal site. Benign mediastinal teratoma accounts for 60% all tumors. mature has excellent prognosis after surgical excision. We present a case 20-year-old woman diagnosed as benign which compressed main pulmonary trunk. The patient underwent
Sepsis is a life-threatening condition and remains major cause of mortality. The aim this study was to evaluate the role biomarkers in diagnosis sepsis septic shock patients admitted emergency department (ED). Medical records who underwent measurement serum including lactic acid, C-reactive protein, procalcitonin (PCT), presepsin ED between May 2019 2020 were retrospectively reviewed. Patients subdivided into 3 groups; non-sepsis, sepsis, according new definition using sequential organ...
Objectives: There have been few clinical studies of ECMO-related alterations the PK meropenem and conflicting results were reported. This study investigated pharmacokinetics (PK) in critically ill adult patients receiving extracorporeal membrane oxygenation (ECMO) used Monte Carlo simulations to determine appropriate dosage regimens. Methods: After a single 0.5 or 1 g dose meropenem, 7 blood samples drawn. A population model was developed using nonlinear mixed-effects modeling. The...
Although the primary cause of acute coronary syndrome is atherosclerotic disease, it important to include other causes myocardial infarction. This report describes case a 53-year-old man with myeloid leukemia, who was referred our cardiology department for treatment infarction ST segment elevation on an electrocardiogram. Portable echocardiography showed large areas vegetation anterior mitral leaflet, while angiography demonstrated total occlusion left descending artery. A histologic...
A pulmonary artery aneurysm is an uncommon anomaly. The clinical manifestations are mostly nonspecific, and management controversial. We report a case of 67-year-old woman with main who did not take surgical intervention. Subsequently, there was no increase in size for 3 years.
Hand-foot-and-mouth disease, a highly contagious viral infection, occurs more common in children than adults.However, there was recent outbreak of Coxsackievirus A6induced infection with an atypical presentation among the adult population.Stevens-Johnson syndrome is severe mucocutaneous disease characterized by extensive necrosis and detachment epidermis, this condition commonly caused medications.Herein, we describe 30-year-old male patient taking allopurinol for management gout.The...
Inhalation injury from smoke or chemical products and carbon monoxide poisoning are major causes of death in burn patients fire accidents. Respiratory tract injuries inhalation can lead to acute respiratory distress syndrome cytokine storm syndrome. In the case failure needing mechanical ventilation accompanied by storm, mortality is high immediate adequate treatment at emergency department very important.This report describes a followed 34-year-old Korean male patient who was house fire,...
Donor lymphocyte infusion (DLI) is performed to augment an anti-tumor immune response or ensure donor stem cells remain engrafted following allogeneic cell transplantation but may induce graft-versus-host disease (GVHD) involving skin, intestine, and liver.Although hepatic involvement of GVHD can manifest as mild severe hepatitis, few reports have mentioned acute liver dysfunction with encephalopathy.We experienced a case semicoma after DLI in patient relapsed multiple myeloma...
Emphysematous prostatitis with an abscess is extremely rare but lethal infection, characterized by the accumulation of gas and purulent exudates. Due to its rarity, severity, nonspecific presentation, prompt diagnosis treatment are crucial achieve favorable clinical outcomes. This report presents a 43-year-old male hemodialysis-dependent end-stage kidney disease who reported 3-day history fever, urinary incontinence, dysuria, dyspnea. His condition rapidly deteriorated due septic shock...
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with poor prognosis and cough the one of most common major symptoms in IPF. The aim this study was to evaluate clinical efficacy Mixture Ivy Leaf Extract Coptidis rhizome (Synatura®) patients This prospective, open-label, single-center, single-arm Korea from October 2019 September 2020. IPF chronic bronchitis were enrolled. Between baseline eight weeks after use Synatura®, measures regarding health-related quality...
Membranous glomerulonephritis is one of the most common causes nephrotic syndrome in adults.Pulmonary alveolar proteinosis (PAP) a rare lung disease which abnormal accumulation surfactant occurs within alveoli.We describe 61-year-old man with concurrent membranous and PAP, very rare; both are pathophysiologically related to an immune response.A patient came hospital leg edema but no respiratory symptoms.Chest X-ray CT showed classical PAP findings, ground-glass opacities interlobular septal...
Ulcerative colitis (UC) is a chronic idiopathic inflammatory disorder of the colon with variable clinical course exacerbation and remission. Extraintestinal manifestations UC, including hematological disorders, such as rare immune thrombocytopenic purpura (ITP), may be presenting symptoms. We encountered case 23-year-old man UC who showed typical symptoms endoscopic findings. Despite receiving steroid treatment, patient developed severe thrombocytopenia. He was diagnosed ITP, characterized...
Background: Circulating bacterial DNA fragment is known to be related chronic systemic inflammatory state of end-stage renal disease (ESRD) patients undergoing dialysis.We conducted a study based on the hypothesis that if dialysis undergo kidney transplantation (KT), conditions will resolved and circulating levels drop.In addition, resolution condition reduces use antibiotics, it expected diversity intestinal flora can restored, this measured by metagenomics analysis fragments.Methods:...
Abstract Background Gastrointestinal dysbiosis due to antibiotics and mucosal injury by intensive chemotherapy are important risk factors for Enterococcal infection in patients with acute leukemia. However, there is still disagreement about trends of incidence outcome bloodstream (BSI) Enterococcus species. This study aimed identify the changes epidemiology BSI estimate long-term impact on an leukemia cohort. Methods All adult diagnosed (N = 512) between 2014 2018 at Catholic Hematology...