- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Molecular Biology Techniques and Applications
- RNA modifications and cancer
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Colorectal Cancer Treatments and Studies
- Aquaculture disease management and microbiota
- Acoustic Wave Resonator Technologies
- Identification and Quantification in Food
- Epigenetics and DNA Methylation
- Advanced Biosensing Techniques and Applications
- Genetic factors in colorectal cancer
- Analytical Chemistry and Sensors
- Microfluidic and Bio-sensing Technologies
- RNA Interference and Gene Delivery
- Extracellular vesicles in disease
- S100 Proteins and Annexins
- MicroRNA in disease regulation
- SARS-CoV-2 detection and testing
- CRISPR and Genetic Engineering
- Digital Imaging for Blood Diseases
- Spectroscopy Techniques in Biomedical and Chemical Research
- Microfluidic and Capillary Electrophoresis Applications
- Cancer, Hypoxia, and Metabolism
Army Medical University
2015-2025
Daping Hospital
2019-2025
Hainan University
2025
Shanghai Institute of Technology
2025
Jianghan University
2024
Hunan Agricultural University
2017-2024
ZheJiang Institute For Food and Drug Control
2024
The Seventh Affiliated Hospital of Sun Yat-sen University
2023-2024
Sun Yat-sen University
2023-2024
Lanzhou Petrochemical Polytechnic
2022-2024
Abstract The development of artificial intelligence-enabled medical health care has created both opportunities and challenges for next-generation biosensor technology. Proteins are extensively used as biological macromolecular markers in disease diagnosis the analysis therapeutic effects. Electrochemical protein biosensors have achieved desirable specificity by using specific antibody–antigen binding principle immunology. However, active centers biomarkers surrounded a peptide matrix, which...
The atherogenic index of plasma (AIP) is an important alternative metabolic biomarker atherosclerosis and cardiovascular diseases. Nevertheless, the correlation between AIP carotid unknown among general population.A total 52,380 community residents, aged ≥ 40 years who underwentcervical vascular ultrasound from December 2017 to 2020 in Hunan China, were selected for retrospective analysis. was calculated as a logarithmically converted ratio triglycerides (TG) high-density...
Herein, we report a facile approach to decorate graphene oxide (GO) sheets with poly(vinyl acetate) (PVAc) by γ-ray irradiation-induced graft polymerization. The content of PVAc in the obtained sample, i.e., grafted GO (GO-g-PVAc) is calculated loss weight thermogravimetric analysis (TGA) curves. A GO-g-PVAc sample degree grafting (DG) 28.5% was well dispersed common organic solvents and dispersions were extremely stable at room temperature without any aggregation, even after standing for 2...
Rice (Oryza sativa L.) is the most widely consumed staple crop for approximately half of world’s population. Many interactions take place in paddy soil, particularly rice mycorrhizosphere region. Arbuscular mycorrhizal fungi (AMF) and soil microbe are among important influential processes that occur, as they significantly influence plant growth structure properties. Their may be crucial importance to sustainable, low-input productivity ecosystems. In this study, we summarize major groups...
Here we demonstrated the potential and applicability of terahertz (THz) spectroscopy to detect four commonly found bacteria in infectious diseases. Besides different spectral characteristics between bacterial species, THz absorption differences for living bacteria, dead powder same species were also investigated. Our results revealed that small water contents cells account distinct discrepancies coefficients, which can be used identification. Furthermore, showed coefficients as a result...
Although conventional lubricant additives containing sulfur and phosphorus elements have been widely utilized to lower friction wear, harmful emissions caused by the lubrication processes resulted in serious environmental concerns. In this work, a series of polymer–nanoparticle networks situ constructed base oil coupling phenylboronic ester-containing telechelic polymers silica or titania nanoparticles via dynamic B–O covalent bonds. These sulfur- phosphorus-free composites appear as form...
A terahertz (THz) spectroscopic study is carried out to analyze DNA mutations in a label-free manner. Three newly designed liquid sample cells are considered and the best selected as carrier for THz transmission analyses. Discrimination based on spectral signatures of single-base single-stranded 20 nt oligonucleotides has been shown possible experimentally. The results clearly attest ability this promising approach analyses molecules. This demonstrated that technology can be potential...
BACKGROUND: MicroRNA (miR)-376 family play crucial roles in cancer formation and progression. OBJECTIVE: To investigate expression patterns of circulating miR-376 members glioma patients, to explore their diagnostic prognostic values. METHODS: Expression serum sampl es from 100 patients 50 healthy controls were detected by quantitative real-time PCR. RESULTS: Serum miR-376a, miR-376b miR-376c significantly lower than those (all P< 0.05). Their could efficiently distinguish the according...
The COVID-19 pandemic has spread worldwide, and rapid detection of the SARS-CoV-2 virus is crucial for infection surveillance epidemic control. This study developed a centrifugal microfluidics-based multiplex reverse transcription recombinase polymerase amplification (RT-RPA) assay endpoint fluorescence E, N, ORF1ab genes SARS-CoV-2. microscope slide-shaped microfluidic chip could simultaneously accomplish three target one reference human gene (i.e., ACTB) RT-RPA reactions in 30 min,...
Urinary proteins are predictive and prognostic markers for diabetes nephropathy. Conventional methods the quantification of urinary proteins, however, time-consuming, most require radioactive labeling. We designed a label-free piezoelectric quartz crystal microbalance (QCM) immunosensor array to simultaneously quantify 4 proteins.We constructed 2 x 5 model fabricated with disposable crystals microalbumin, alpha1-microglobulin, beta2-microglobulin, IgG in urine. made calibration curves after...