A5101954657- Urticaria and Related Conditions
- Biosensors and Analytical Detection
- Dermatology and Skin Diseases
- Autoimmune Bullous Skin Diseases
- Cytomegalovirus and herpesvirus research
- Food Allergy and Anaphylaxis Research
- Acne and Rosacea Treatments and Effects
- Herpesvirus Infections and Treatments
- Mast cells and histamine
- Bacteriophages and microbial interactions
- Systemic Lupus Erythematosus Research
- Synthesis and biological activity
- Peripheral Nerve Disorders
- Chromatography in Natural Products
- Healthcare professionals’ stress and burnout
- Spinal Cord Injury Research
- Cyclopropane Reaction Mechanisms
- Shoulder Injury and Treatment
- Medical Education and Admissions
- Diversity and Career in Medicine
- Fluorine in Organic Chemistry
- Advanced biosensing and bioanalysis techniques
- Bone Tumor Diagnosis and Treatments
- Radical Photochemical Reactions
- Atherosclerosis and Cardiovascular Diseases
Army Medical University
2011-2024
Southwest Hospital
2011-2024
WuXi AppTec (China)
2024
Huazhong Agricultural University
2018
Zhoushan Hospital
2017
Wenzhou Medical University
2017
University of Notre Dame
2015
Shanghai Medical College of Fudan University
2014
Zhejiang Hospital
2013
Second Hospital of Liaohe Oilfield
2011
Rapid emergence of antibiotic resistance is one the most challenging global public health concerns. In particular, vancomycin-resistant Enterococcus faecium infections have been increasing in frequency, representing 25% enterococci intensive care units. A novel class 1,2,4-triazolo[1,5-a]pyrimidines active against E. reported herein. We used a three-component Biginelli-like heterocyclization reaction for synthesis series these derivatives based on reactions aldehydes, β-dicarbonyl compounds,...
Health care workers are at the frontline in fight against infectious disease, and as a result high risk of infection. During 2014-2015 Ebola outbreak West Africa, many health contracted Ebola, some fatally. However, no members Chinese Anti-Ebola medical team, deployed to provide vital Liberia were infected. This study aims understand how this zero infection rate was achieved.Data collected through 15 in-depth interviews with participants from People's Liberation Army China team which...
Osteolysis at the tendon-bone interface can impair pullout strength during healing and lead to surgery failure, but effects of clinical treatments are not satisfactory. Mesenchymal stem cell (MSC)-derived exosomes have been used as potent feasible natural nanocarriers for drug delivery proven enhance strength, indicating that MSC-derived could be a promising therapeutic strategy. In this study, we explored Scleraxis (Scx) dynamically expressed in PDGFRα(+) bone marrow-derived mesenchymal...
<b><i>Introduction:</i></b> Atopy is an important and non-negligible clinical phenomenon in chronic spontaneous urticaria (CSU). However, the characteristics significance of atopy patients with CSU have not been fully described. This study aimed to analyze CSU. <b><i>Methods:</i></b> A descriptive cross-sectional design was used. The enrolled 176 All underwent total IgE, specific autologous serum skin tests (ASSTs). relationships between atopy,...
Objectives Hospitals devoted to maternal and child health represent unique healthcare institutions in China. Healthcare professionals these hospitals attend services for women children, also provide technical support district children’s as well family planning. However, few studies have examined occupational burnout among doctors employed hospitals. This research addresses the gap literature. Methods A cross-sectional survey of obstetricians paediatricians from 11 across China was conducted...
A cascade Michael addition/alkylation reaction between 3-chlorooxindoles and α-cyano chalcones catalyzed using a multifunctional quinine-derived aminoindanol-thiourea substance was investigated. series of spirooxindoles incorporating densely substituted cyclopropane motif were efficiently obtained with moderate to excellent diastereo- enantioselectivity further transformed products versatile structural diversity. Density functional theory (DFT) calculations indicated that the tentative...
Abstract Symptomatic dermographism (SD) is the most common form of chronic inducible urticarias. The etiology this disease has rarely been reported in literature. Minocycline widely used treatment acne, rosacea, and other inflammatory skin diseases. Herein we report four cases SD onset during minocycline administration. These were young women their 20s to 30s who taking orally for acne vulgaris or rosacea. They all experienced 2–3 weeks after drug, then complete disappearance 1 month...
Hepatopulmonary syndrome (HPS) is a serious complication of advanced liver disease, which markedly increases mortality. Pulmonary vascular remodelling (PVR) induced by circulating mediators plays an important role in the pathogenesis HPS, while underlying mechanism remains undefined. In present study, we reported that endothelin-1 (ET-1) up-regulated and annexin A1(ANXA1) down-regulated HPS rat, ET-1 decreases ANXA1 expression dose-dependent manner rat pulmonary arterial smooth muscle cells...
Abstract Fibular (peroneal) intraneural ganglia classically present with predominant tibialis anterior weakness, for which there is no clear anatomical explanation. We identified a new imaging pattern, consisted of involvement proximal branch, in patients fibular ganglia. This study characterizes the cystic this branch and evaluates its significance. The magnetic resonance (MRI) clinical data 23 were retrospectively reviewed. was consistently involved cyst, involvement, although variable,...
Background: The incidence of herpes zoster (HZ) in systemic lupus erythematosus (SLE) patients is high, and the symptoms are usually severe resistant to treatment, prognosis poor. Ultraviolet (UV) A1 a band UV light, UVA1 phototherapy has been widely used treat various inflammatory skin diseases. Objective: At present, considered as potential adjuvant therapy for HZ SLE patients. To best our knowledge, this first case report concerning successful application treatment secondary SLE. Methods:...
Chronic urticaria (CU) is not traditionally classified as an allergic disease, but emerging evidence suggests a link to atopy. The quintessential marker of atopy IgE sensitization, there scarce information on the sensitization characteristics CU.
Introduction: Bacteremia is a common complication in systemic lupus erythematosus (SLE) patients, causing high morbidity and mortality. We investigated characteristics, pathogens, sites of infection using cohort 64 female adults from single university hospital China.
 Methodology: SLE patients who had at least one episode bacteremia (n = 16) were compared with non-bacteremia 48) case-control fashion, matching for age diagnosis time admission. Demographic clinical laboratory data,...
Objectives: To evaluate the differentiating roles of computed tomography (CT) for invasive adenocarcinomas (IACs) lung from preinvasive lesions or minimally (MIAs) manifesting as part-solid ground-glass nodules (GGNs). Patients and Methods: All 230 were pathologically confirmed. Their size, CT parameters morphological features compared among three groups. Optimal cut-off values calculated with diagnostic value. Results: The diameter GGN lesion maximum solid part, well part differed...
<b><i>Background:</i></b> Acute urticaria (AU) may be associated with atopy, but the relationship between atopic status and clinical features of disease has not been fully described. <b><i>Objectives:</i></b> The aim study was to determine proportion atopy in AU patients see whether is related characteristics it an impact on outcome disease. <b><i>Materials Method:</i></b> A retrospective analysis performed. Demographic...
To investigate the drug resistance of enteric bacilli and its relation to gene cassette in variable region molecular evolution class-I integron.K-B assay was applied measure E.coli, E.cloacae A.baumannii isolated against twelve antibiotics. The integron cassettes were detected by PCR sequencing amplification products. genes integrons analyzed using Clustal X MEGA software.54.2%-100% isolates resistant penicillin cephem antibiotics, while E.coli had rates 41.6%-62.5% 62.5%(15/24) 67.9%(19/28)...