Zhongxiang Sun

ORCID: 0000-0002-0176-581X
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About
Contact & Profiles
Research Areas
  • Insect Resistance and Genetics
  • Insect-Plant Interactions and Control
  • Insect Pest Control Strategies
  • Insect and Pesticide Research
  • HIV/AIDS drug development and treatment
  • Quinazolinone synthesis and applications
  • Hepatitis C virus research
  • Insect symbiosis and bacterial influences
  • Mycorrhizal Fungi and Plant Interactions
  • Plant Parasitism and Resistance
  • Neurobiology and Insect Physiology Research
  • Synthesis and Biological Evaluation
  • Insect and Arachnid Ecology and Behavior
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Synthesis and Reactivity of Heterocycles
  • Bacteriophages and microbial interactions
  • Catalytic C–H Functionalization Methods
  • Catalytic Cross-Coupling Reactions
  • Allelopathy and phytotoxic interactions
  • Aluminum toxicity and tolerance in plants and animals
  • Plant Virus Research Studies
  • RNA and protein synthesis mechanisms
  • Silicon Effects in Agriculture
  • Chemical Synthesis and Analysis
  • Plant-Microbe Interactions and Immunity

Yunnan Agricultural University
2022-2025

Qiqihar University
2025

Shenyang Ligong University
2023-2024

Fujian Agriculture and Forestry University
2015-2023

Beijing University of Technology
2023

Merck & Co., Inc., Rahway, NJ, USA (United States)
2016-2021

Sun Yat-sen University
2011-2018

Roots of most terrestrial plants form symbiotic associations (mycorrhiza) with soil- borne arbuscular mycorrhizal fungi (AMF). Many studies show that colonization enhances plant resistance against pathogenic fungi. However, the mechanism mycorrhiza-induced disease remains equivocal. In this study, we found inoculation AMF Funneliformis mosseae significantly alleviated tomato (Solanum lycopersicum Mill.) early blight caused by Alternaria solani Sorauer. pre-inoculation led to significant...

10.3389/fpls.2015.00786 article EN cc-by Frontiers in Plant Science 2015-09-28

Frankliniella occidentalis is a highly destructive and invasive agricultural pest that has developed resistance to variety of insecticide classes. Different planting structures use frequency can directly affect the development F. occidentalis. In this study, susceptibility three field strains occidentalis, collected over one year (April November) from habitat conditions (facility agriculture area, FA; open crop OF; agroforestry intersection AI), spinetoram, spinosad, emamectin benzoate,...

10.3390/insects14070643 article EN cc-by Insects 2023-07-17

As an r-strategy insect species, the brown planthopper (BPH) Nilaparvata lugens (Stål) is a serious pest of rice crops in temperate and tropical regions Asia Australia, which may be due to its robust fecundity. Here we combined 2-DE comparative proteomic RNA-seq transcriptomic analyses identify fecundity-related proteins genes. Using high- low-fecundity populations as sample groups, total 54 75 were significantly altered third sixth day brachypterous female stages, respectively, 39 these...

10.1021/pr400561c article EN Journal of Proteome Research 2013-10-02

Abstract The target of rapamycin (TOR) positively controls cell growth in response to nutrients such as amino acids. However, research on the specific sensed by TOR is limited. Glutamine (Gln), a particularly important acid involved metabolism organisms, synthesised and catalysed exclusively glutamine synthetase (GS) our previous studies have shown that Gln may regulate fecundity vivo levels brown planthopper (BPH) Nilaparvata lugens. Until now, it has remained unclear whether activates or...

10.1038/srep10694 article EN cc-by Scientific Reports 2015-05-29

Silicon (Si) application can significantly enhance rice resistance against herbivorous insects. However, the underlying mechanism is elusive. In this study, silicon transporter mutant OsLsi1 and corresponding wild-type (WT) were treated with without Si to determine effects on leaffolder (LF), Cnaphalocrocis medinalis (Guenée) (Lepidoptera: Pyralidae). WT plants promoted plant growth, upregulated expression level of increased accumulation in leaves roots, as well effectively reduced LF weight...

10.3389/fpls.2019.00652 article EN cc-by Frontiers in Plant Science 2019-05-24

Although the induction of cytochrome P450 monooxygenases involved in insect detoxification has been well documented, underlying regulatory mechanisms remain obscure. In Spodoptera litura, CYP321A subfamily members were effectively induced by exposure to flavone, xanthotoxin, curcumin, and λ-cyhalothrin, while knockdown genes increased larval susceptibility these xenobiotics. Homology modeling molecular docking analyses showed that four xenobiotics could stably bind enzymes. Furthermore, two...

10.1021/acs.jafc.3c05423 article EN Journal of Agricultural and Food Chemistry 2023-10-04

Abuse of chemical fertilizers and insecticides has created many environmental human health hazards. We hypothesized that high nitrogen (N) in crops changes insect gut microbiota leading to enhanced insecticide tolerance. investigated the effect N maize on tolerance polyphagous pest Spodoptera litura. Bioassays showed applied both plants artificial diets significantly larval growth but reduced sensitivity methomyl. High promoted bacterial abundance genus Enterococcus. Inoculation with two...

10.1016/j.isci.2021.103726 article EN cc-by-nc-nd iScience 2022-01-01

The involvement of carboxylesterases (CarEs) in resistance to chlorpyrifos has been confirmed by the synergism analysis Nilaparvata lugens. However, function specific CarE gene and transcriptional regulatory mechanism are obscure. Herein, expression patterns 29 genes susceptible chlorpyrifos-resistant strains were analyzed. Among them, CarE3, CarE17 CarE19 overexpressed resistant strain, knockdown either RNA interference significantly increased susceptibility chlorpyrifos. Remarkably,...

10.1016/j.ecoenv.2022.113738 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2022-06-06

The rhizospheric microbial community affects the population establishment of invasive plants in introduced areas, among which Bacillus has numerous functions promoting plant growth. This study isolated and enriched soil Ageratina adenophora native accompanying Rabdosia amethystoides. effects these communities on growth competition A. R. amethystoides were evaluated pot experiments. results showed that number diversity higher than those (A. adenophora: 122 strains soil, 16 taxa;...

10.3389/fpls.2022.882255 article EN cc-by Frontiers in Plant Science 2022-06-14

We previously reported that the general odorant-binding protein GOBP2 enhances chlorpyrifos tolerance in Spodoptera litura by perceiving herbicides. However, direct interaction between and pesticides remains unknown. Herein, we verified effect of binding to on herbicide-induced insecticide S. litura. Fluorescence competitive assays indicated exhibits high affinities herbicide trifluralin insecticides indoxacarb, chlorpyrifos, fipronil, with Ki values ranging from 1.95 13.01 μM. Moreover,...

10.1021/acs.jafc.4c12251 article EN Journal of Agricultural and Food Chemistry 2025-02-06

As an significant tool for communicating and disseminating information, language could not only symbolize general literacy of individuals, but also reflect the socio-cultural profile. With awakening females in English countries, some sexism words, especially those which discriminate against women are concerned. This paper is going to take sexist vocabulary as entry point, systematically analyse features composition semantics, then explore reasons behind countermeasures eliminate linguistic...

10.54254/2753-7048/2025.21112 article EN cc-by Lecture Notes in Education Psychology and Public Media 2025-02-21

ABSTRACT As a migratory agricultural pest, the fall armyworm has been in spotlight since it invaded Africa 2016. Invasive populations have now colonized much of Eastern Hemisphere, causing severe damage to wide range crops. However, there is still disagreement internationally on origin and mode invasion populations, especially from Americas China. In this study, we provided an in‐depth insight into hemisphere based genome‐wide data 124 individuals collected 14 sites across three continents...

10.1111/eva.70086 article EN cc-by Evolutionary Applications 2025-02-01

The fall armyworm (Spodoptera frugiperda, FAW) is one of the most devastating invasive pests in world, owing to its extraordinary migration performance. Research has clarified migratory pathways and external environmental factors affecting FAW migration. However, internal genes loci regulating or reside remain largely unknown. In this study, we used a tethered flight mill system distinguish resident individuals, which exhibit significant differences flight-related traits such as distance,...

10.1002/ps.8682 article EN Pest Management Science 2025-02-24

Plants produce secondary metabolites to provide chemical defense against herbivorous insects, whereas insects can induce the expression of detoxification metabolism-related unigenes in counter plant xenobiotics. Tomatine is an important metabolite tomato (Lycopersicon esculentum L.) that protect from bacteria and insects. However, mechanism underlying adaptation Spodoptera litura, a major pest, tomatine largely unclear. In this study, we first found levels tomatoes subjected S. litura...

10.3389/fphys.2019.00008 article EN cc-by Frontiers in Physiology 2019-01-22

A practical approach toward the synthesis of 2-arylazoles via direct arylation is described. The transformation relies on a Pd/Cu cocatalyst system that operates with low catalyst loadings. reaction conditions were found to be tolerant wide range functional groups and nitrogen-containing heterocycles commonly employed in drug discovery setting.

10.1021/acs.orglett.1c00100 article EN Organic Letters 2021-03-05

The fall armyworm (FAW), Spodoptera frugiperda, is one of the most important invasive species and causes great damage to various host crops in China. In this study, diversity function gut bacteria 5th instar larvae FAW fed on maize, wheat, potato tobacco leaves were analyzed through 16S rRNA sequencing. A total 1324.25 ± 199.73, 1313.5 74.87, 1873.00 190.66 1435.25 139.87 operational taxonomic units (OTUs) from these four different plants detected, respectively. Firmicutes, Proteobacteria...

10.3390/insects13040373 article EN cc-by Insects 2022-04-11

Abstract Background Fall armyworm, Spodoptera frugiperda , a formidable agricultural pest, has developed resistance to various synthetic insecticides. However, how S. utilizes its limited energy and resources deal with insecticides remains largely unexplored. Results We utilized transcriptome sequencing decipher the broad‐spectrum adaptation mechanism of eight distinct modes‐of‐action. Analysis Venn diagram revealed that 1014 upregulated genes 778 downregulated were present in treated at...

10.1002/ps.8054 article EN Pest Management Science 2024-03-01

Abstract Background The brown planthopper (BPH), Nilaparvata lugens , is the most devastating rice pest in many areas throughout Asia. reproductive system of female N. consists a pair ovaries with 24-33 ovarioles per ovary individuals which determine its fecundity. fork head (Fox) transcriptional regulatory molecule, regulates and controls physiological processes eukaryotes. Fox family has several subclasses members, factors have been reported to be involved regulating Results We cloned gene...

10.1186/1471-2199-12-53 article EN cc-by BMC Molecular Biology 2011-12-01

Type 2 diabetes mellitus (T2DM) is an ever increasing worldwide epidemic, and the identification of safe effective insulin sensitizers, absent weight gain, has been a long-standing goal research. G-protein coupled receptor 120 (GPR120) recently emerged as potential therapeutic target for treating T2DM. Natural occurring, more recently, synthetic agonists have associated with sensitizing, anti-inflammatory, fat metabolism effects. Herein we describe design, synthesis, evaluation novel...

10.1021/acsmedchemlett.6b00360 article EN ACS Medicinal Chemistry Letters 2016-11-17
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