Julian Thalhammer
- Immunodeficiency and Autoimmune Disorders
- Autoimmune and Inflammatory Disorders Research
- Immune Cell Function and Interaction
- Abdominal Trauma and Injuries
- Histiocytic Disorders and Treatments
- Poisoning and overdose treatments
- Platelet Disorders and Treatments
- Viral-associated cancers and disorders
- Parvovirus B19 Infection Studies
- Restraint-Related Deaths
- Glioma Diagnosis and Treatment
- Animal health and immunology
- Hepatitis C virus research
- Chronic Lymphocytic Leukemia Research
- Neonatal Health and Biochemistry
- Epigenetics and DNA Methylation
- Boron Compounds in Chemistry
- Liver physiology and pathology
- Traumatic Ocular and Foreign Body Injuries
- Hemoglobinopathies and Related Disorders
- Plant tissue culture and regeneration
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Plant Genetic and Mutation Studies
- Plant Pathogens and Resistance
Centre de Recherche en Cancérologie de Lyon
2024
Institut d’Hématologie et d’Oncologie Pédiatrique
2023-2024
Centre Léon Bérard
2024
University of Freiburg
2019-2023
University Medical Center Freiburg
2019-2023
Great North Children's Hospital
2023
Newcastle University
2023
Klinik und Poliklinik für Kinder- und Jugendmedizin
2021
Hôpital Necker-Enfants Malades
2016
Klinikum rechts der Isar
2015
Ductular reactions (DRs) are observed in virtually all forms of human liver disease; however, the histogenesis and function DRs injury not entirely understood. It is widely believed that contain bipotential progenitor cells (LPCs) serve as an emergency cell pool to regenerate both cholangiocytes hepatocytes may eventually give rise hepatocellular carcinoma (HCC). Here, we used a murine model allows highly efficient specific lineage labeling biliary compartment analyze their potential...
The identification and characterization of rare immune cell populations in humans can be facilitated by their growth advantage the context specific genetic diseases. Here, we use autoimmune lymphoproliferative syndrome to identify a population FAS-controlled TCRαβ+ T cells. They include CD4+, CD8+, double-negative cells defined CD38+CD45RA+T-BET− expression pattern. These unconventional are present healthy individuals, generated before birth, enriched lymphoid tissue, do not expand during...
In recent years, the application of rare cutting restriction enzymes, separation resulting DNA fragments on pulsed-field gels and subsequent Southern blot analysis using radioactively labeled probes have been standard laboratory methods to create long-range physical maps complex genomes. The disadvantages this technology are hazardous handling risks when working with radioactivity long exposure times. paper, we describe use nonradioactively for single-copy sequence detection in a plant...
Cure of hepatoblastoma requires complete macro- and microscopic resection the tumor, without tumor rupture. In case with intra-atrial extension (ITE), "en bloc" hepatic ITE, minimal risk postoperative liver failure, constitutes a surgical challenge. We report on 3 year old child right lobe, ITE through upper Inferior Vena Cava. Initial chemotherapy (SIOPEL IV HR) induced good response, but persisted inside atrium tight adhesions to cardiac wall. "En extended hepatectomy removal...
Abstract BACKGROUND Since 2016, the WHO classification of CNS tumors groups all midline gliomas with H3K27me3 loss under term diffuse glioma (DMG), H3K27-altered. Molecular characteristics enable their sub-classification based on driver mutations, co-driver mutations and epigenetic alterations. Predominantly studied in pons (Diffuse Intrinsic Pontine Glioma, DIPG), where these are mainly pediatric a median overall survival (OS) one year, fewer studies have been conducted non-pontine DMG...