- Retinal Development and Disorders
- Adsorption and Cooling Systems
- Phase Change Materials Research
- Solar Thermal and Photovoltaic Systems
- Retinal Diseases and Treatments
- Ionic liquids properties and applications
- Air Quality and Health Impacts
- Pluripotent Stem Cells Research
- Neuroscience and Neural Engineering
- Toxic Organic Pollutants Impact
- Chemical Synthesis and Reactions
- Per- and polyfluoroalkyl substances research
- Environmental remediation with nanomaterials
- Magnesium Oxide Properties and Applications
- Carbon Dioxide Capture Technologies
- 3D Printing in Biomedical Research
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Energy and Environmental Systems
- Zebrafish Biomedical Research Applications
- Birth, Development, and Health
- RNA regulation and disease
- Nerve injury and regeneration
- Extracellular vesicles in disease
- Aquaculture Nutrition and Growth
Hunan University of Traditional Chinese Medicine
2025
Army Medical University
2016-2025
Southwest Hospital
2016-2025
Dalian Medical University
2023-2025
Chongqing Medical University
2023-2025
Second Affiliated Hospital of Chongqing Medical University
2023-2025
Shenyang University of Technology
2025
Guangdong Research Institute of Water Resources and Hydropower
2024
Systems Engineering Society of China
2024
Guilin University of Technology
2024
Investigations about how to recycle the deactivated nanomaterials are well-needed. This work was designed explore recycling strategy of Mg(OH)2 nanoadsorbent during treating low concentration CrVI solution as an example. It demonstrated that a reversible route between Cr-adsorbed nano-Mg(OH)2 and Cr-desorbed bulk-MgCO3·3H2O can be established by using CO2 phase transformation medium. In each adsorption−desorption cycle, with initial 10 mg·L−1 could enriched over 40 times. An...
Stem cell therapy may replace lost photoreceptors and preserve residual during retinal degeneration (RD). Unfortunately, the degenerative microenvironment compromises fate of grafted cells, demanding supplementary strategies for regulation. Donor cells with both proper regeneration capability intrinsic ability to improve are highly desired. Here, we use surface markers (C-Kit+/SSEA4-) effectively eliminate tumorigenic embryonic enrich progenitor (RPCs) from human stem (hESC)-derived...
Sodium dodecyl sulfate (SDS) and alkylphenol polyoxyethylene ether (OP-10) mixed templates, microencapsulated phase change materials (MEPCMs) with an n-tetradecane core, calcium carbonate (CaCO3) shell were prepared by a self-assembly method. The effects of the core/shell mass ratio SDS/OP-10 on morphology enthalpy synthesized MEPCMs investigated polarized optical microscope (POM) differential scanning calorimetry (DSC), respectively. structure thermal performance systematically...
Increasing evidence demonstrated that PM2.5 could cross the placenta and fetal blood–brain barrier, causing neurotoxicity of embryonic development. The retina, an embryologic extension central nervous system, is extremely sensitive vulnerable to environmental insults. adverse effects exposure on retina during neurodevelopment are still largely unknown. Our goal was investigate effect human retinal development, which recapitulated by stem cell (hESC)-derived organoids (hEROs). In present...
Increasing evidence in animal models has suggested that polybrominated diphenyl ethers (PBDEs), a class of brominated flame retardants, can cause retinotoxicity. However, data on the influence PBDE treatment human retinal development are scarce due to lack appropriate models. In present study, we report utilization embryonic stem cell-derived organoids (hESC-ROs) for toxicity assessment most common congener (BDE-47) during early stages development. Exposure BDE-47 decreased thickness and...
Perfluorooctanoic acid (PFOA) is widely present in the environment and has been reported to induce hepatic toxicity animals humans. In this study, mice were orally administered different concentrations of PFOA (2.5, 5, or 10 mg/kg/day). Histological examination showed that exposure for 14 consecutive days led serious hepatocellular injury obvious inflammatory cell infiltration. addition, malondialdehyde formation hydrogen peroxide generation, indicators oxidative stress, significantly...
Perfluorooctane acid (PFOA) is a hazardous environmental pollutant that has been reported to exert adverse effects on animal and human health. In this study, male mice were orally administered different concentrations of PFOA (2.5, 5, or 10 mg/kg/day) evaluate the reproductive toxicity. Exposure for 14 consecutive days obviously disrupted seminiferous tubules reduced sperm count. The highest concentration (10 caused growth retardation diminished absolute testis weight. Furthermore, treatment...
Retinitis pigmentosa (RP) is a progressive hereditary retinal degenerative disease in which photoreceptor cells undergo degeneration and apoptosis, eventually resulting irreversible loss of visual function. Currently, no effective treatment exists for this disease. Neuroprotection inflammation suppression have been reported to delay the development RP. Metformin well-tested drug used treat type 2 diabetes, it has exert beneficial effects neurodegenerative diseases, such as Parkinson's...
A controllable perfusion microfluidic chip with the advantages of precisely controlling fluidic shear stress and oxygen concentration distribution is designed to promote development retinal organoids.