A5100644679- Immune Cell Function and Interaction
- Diverse Approaches in Healthcare and Education Studies
- T-cell and B-cell Immunology
- Mesenchymal stem cell research
- Periodontal Regeneration and Treatments
- FinTech, Crowdfunding, Digital Finance
- Microfinance and Financial Inclusion
- dental development and anomalies
- Diverse Topics in Contemporary Research
- Psychosocial Factors Impacting Youth
- CAR-T cell therapy research
- Digital Marketing and Social Media
- Oral and Maxillofacial Pathology
- Sharing Economy and Platforms
- Immunotherapy and Immune Responses
- Surface and Thin Film Phenomena
- Cleft Lip and Palate Research
- Immune Response and Inflammation
- Molecular Sensors and Ion Detection
- Education, Safety, and Science Studies
- Advanced biosensing and bioanalysis techniques
- Temporomandibular Joint Disorders
- ZnO doping and properties
- Electrokinetic Soil Remediation Techniques
- Consumer Perception and Purchasing Behavior
Seoul National University Dental Hospital
2011-2025
Seoul National University
2006-2024
University of California, San Francisco
2022
National Cancer Institute
2013-2022
Center for Cancer Research
2017-2022
Samsung Medical Center
2022
University of Illinois Chicago
2022
Myongji University
2022
EuBiologics (South Korea)
2022
Peking University
2017-2021
It was reported that postnatal stem cells are present in adult tissues such as bone marrow, liver, muscle, dental pulp, and periodontal ligament. We isolated from human pulp (DPSC), ligament (PDLSC), periapical follicle (PAFSC), the surrounding mandibular marrow (MBMSC) to ascertain their properties. Immunocytochemistry proved existence of these cell populations using STRO-1 a marker. These also expressed mesenchymal (MSC) markers CD29 CD44. The showed self-renewal capabilities...
The platelet-rich fibrin (PRF) is known as a rich source of autologous cytokines and growth factors universally used for tissue regeneration in current clinical medicine. However, the microstructure PRF has not been fully investigated nor have studied key molecules that differ from plasma. We fabricated under Choukroun's protocol produced its extract (PRFe) by freezing at -80°C. conventional histological, immunohistological staining, scanning electron microscopy images showed PRF, appearing...
Periodontitis is the most common cause for tooth loss in adults and advanced types affect 10-15% of worldwide. The attempts to save regenerate periodontal apparatus including cementum, ligament, alveolar bone reach dental tissue-derived stem cell therapy. Although there have been several periodontitis models suggested, apical involvement root especially challenging be regenerated therapy state has never investigated. Three kinds adult cells (aDSCs) were obtained from extracted immature...
This communication presents a fluorescent chemosensor for detecting Pb(II) and Hg(II) in aqueous solutions. The sensor showed turn-on response to by an enhancement of emission intensity at 380 nm intensities 475 nm. We have first characterized unique function tryptophan as ligand well quencher recognition change metal binding event.
Prior research in behavioral economics has examined the effects of nudging and diverse aspects choice on individuals' decisions behaviors. Based this premise, current offers a novel timely view by examining how communication messages public service advertisements (PSAs) can alter perception threat under uncertain situations such as SARS-CoV-2 coronavirus pandemic. This article investigates role additional relative statistical information stockpiling intention. First, we examine whether there...
Abstract Current field sampling techniques are not readily able to produce high-quality undisturbed granular soil specimens for laboratory testing at an affordable cost. Accordingly, numerous specimen reconstitution methods have been developed use in the laboratory. Among these methods, moist tamping has advantage that it is relatively easy control global density achieved, even loose specimens, although unfortunately method also qualitatively shown yield less uniform specimens. This paper...
Calcium hydroxide has been extensively and steadily used for direct pulp capping in modern clinical dentistry. As it was known to have potential induce hard tissue repair, this chemical applied the exposed dental is expected be regenerated above pulp. During reparative process of pulp, primary odontoblasts that were lost as a result extensive damage are replaced with newly differentiated odontoblast-like cells. This follow sequential steps proliferation, migration, differentiation progenitor...
Trichostatin A (TSA) is a potent histone deacetylase (HDAC) inhibitor with broad spectrum of epigenetic activities known to regulate diverse cellular mechanisms, including differentiation mesenchymal stem cells. In this study, we demonstrate that TSA promotes proliferation and odontoblast human dental pulp cells (hDPSCs) in vitro has the ability enhance dentin formation vivo during tooth development. We observed increased expression proliferating cell nuclear antigen cyclin D1 hDPSCs at...
Fluorescent chemosensors (1 and 2, Py-(Arg)nGlyGlyGly(Arg)nLys(Py)-NH2, n = 2 3) bearing two pyrene (Py) labeled heparin-binding peptides were synthesized for the sensitive ratiometric detection of heparin. The peptidyl 2) sensitively detected nanomolar concentrations heparin in aqueous solutions serum samples via a response. In 100% at pH 7.4, both exhibited significant excimer emission 486 nm as well weak monomer absence Upon addition into solution, increased with blue shift (10 nm) 376...
This research draws data from survey responses and actual transaction to examine the effect of primary motivations on funding behavior in reward-based crowdfunding platforms. Findings show that altruistic are associated with early funding, larger stages. In contrast, reward late across Furthermore, women funders stronger relationships between timing, especially advances understandings about crowdfunding, individual funder theories motivation. Practically, findings suggest project creators...
Platelet-rich plasma (PRP) is fabricated from autologous blood and extensively used to promote soft hard tissue healing. In the dental field, PRP widely combined with implant installation bone graft. This study will evaluate biologic effect of on proliferation differentiation human stem cells, find key cytokines inducing these effects estimate clinical feasibility for engineering.Venous was obtained four individuals each fabricated. The cells were periodontal ligament (PDL) pulp surgically...
Zbtb16 encodes the zinc-finger protein PLZF, which is often used as a lineage marker for innate-like T cells and specifically required generation of invariant natural killer (iNKT) in thymus. Here, we report that not only PLZF expression itself but also relative abundance proteins plays critical roles iNKT cell development. Utilizing hypomorphic allele, PLZFGFPCre, produces at half level wild-type show decreased results significant decrease numbers, further associated with profound...
The coronavirus disease 2019 (COVID-19) pandemic has accelerated digital transformation (DT). We investigated the trend of public interest in technologies regarding DT and Koreans' experiences their perceptions future impact these technologies. Using Google Trends, relative search volume (RSV) for topics including "coronavirus," "artificial intelligence," "cloud," "big data," "metaverse" were retrieved period from January 2020 to 2022. A survey was conducted assess population's knowledge,...
518 Background: Notwithstanding the pressing need for adjuvant therapy hepatocellular carcinoma (HCC), most therapies, including atezolizumab/bevacizumab, have failed. Meanwhile, immunotherapy utilizing autologous cytokine-induced killer (CIK) cells HCC improved recurrence-free survival (RFS) in a previously reported randomized controlled trial (RCT) and real-world data. This study aimed to assess longer-term outcomes of RCT elucidate underlying mechanisms sustained effects CIK cell...