A5062579404- Environmental Toxicology and Ecotoxicology
- Medieval Literature and History
- Fungal Infections and Studies
- Garlic and Onion Studies
- Heavy metals in environment
- Aquatic Invertebrate Ecology and Behavior
- Plant and animal studies
- Antifungal resistance and susceptibility
- Space Science and Extraterrestrial Life
- Parasitic Infections and Diagnostics
- Photoreceptor and optogenetics research
- Genetic Associations and Epidemiology
- Light effects on plants
- Cardiac Imaging and Diagnostics
- Birth, Development, and Health
- Photosynthetic Processes and Mechanisms
- Blood Pressure and Hypertension Studies
- Origins and Evolution of Life
- Pediatric Urology and Nephrology Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Female Genital Mutilation/Cutting Issues
- Trace Elements in Health
- Phosphodiesterase function and regulation
- Mollusks and Parasites Studies
- Plant Parasitism and Resistance
National Library of Scotland
2024
University of Oxford
2020-2024
British Academy
2024
British Library
2024
Cambridge College
2024
University of Cambridge
2024
Society of Antiquaries
2024
Royal Society
2024
Medical Research Council
2021-2022
Churchill Hospital
2020-2022
The Mexico City Prospective Study is a prospective cohort of more than 150,000 adults recruited two decades ago from the urban districts Coyoacán and Iztapalapa in
Whole garlic (Allium sativum L.) extract and some of its components were assayed for antigiardial activity. gave an IC50 at 24 h 0·3 mg ml−1. Most the inhibitory to organism, especially allyl alcohol mercaptan, with values 7 μg ml−1 37 respectively. Studies calcofluor white indicated that whole collapse transmembrane electrochemical membrane potential (Δψ) as by uptake fluorochrome. Electron microscopy allowed morphological changes occur inhibition be recorded. Both surface topography...
Aims: To determine the effects of fresh and freeze‐dried extracts Allium sativum on physiology morphology Candida albicans. Methods Results: Inhibition growth in glucose‐yeast extract‐peptone was measured using a multiwell plate reader. Scanning transmission electron microscopy investigations indicated loss structural integrity. Gas chromatography‐mass spectrometry employed to separate quantify putative inhibitory sulphur‐containing components. Conclusions: Fresh garlic extract has greater...
Christine Clayton *, Mark Adams , Renata Almeida Theo Baltz Mike Barrett Patrick Bastien Sabina Belli Stephen Beverley Nicolas Biteau Jenefer Blackwell Blaineau Michael Boshart Frederic Bringaud George Cross Angela Cruz Wim Degrave John Donelson Najib El-Sayed Gioliang Fu Klaus Ersfeld Wendy Gibson Keith Gull Alasdair Ivens Kelly Daniel Lawson Lebowitz Phelix Majiwa Matthews Sara Melville Gilles Merlin Paul Michels Peter Myler Alan Norrish Fred Opperdoes Barbara Papadopoulou Marilyn Parsons...
It is well established that decreased kidney function can increase blood pressure (BP), but it unproven whether moderately elevated BP causes chronic disease (CKD) or glomerular hyperfiltration.311 119 White British UK Biobank participants were included in logistic regression analyses to estimate the odds of CKD (defined as long-term replacement therapy, estimated filtration rate [eGFR]< 60mL/min/1.73m2, urinary albumin:creatinine ratio ≥3 mg/mmol) associated with higher genetically...
The labella of Maxillaria acuminata Lindl., M. cerifera Barb. Rodr. and notylioglossa Rchb.f., all members the alliance, produce a viscid wax-like secretion. Histochemical analysis revealed that chemical composition secretion is similar in three species, consisting largely lipid protein. Light microscopy low-vacuum scanning electron were used to investigate secretory process. In fourth taxon, cf. notylioglossa, transmission showed bodies are associated with smooth endoplasmic reticulum or...
A continuous culture of Saccharomyces cerevisiae IFO 0233, growing with glucose as the major carbon and energy source, shows oscillations respiration a period 48 min. Samples taken at maxima minima indicate that (i) periodic changes do not occur result depletion, (ii) intrinsic differences in respiratory activity washed organisms (iii) inhibitor accumulates during oscillations. Plasma membrane inner mitochondrial membranes generate transmembrane electrochemical potentials; these can be...
Air samples collected aseptically over tropical India at various stratospheric altitudes ranging from 20 to 41 km using cryosampler assemblies carried on balloons flown Hyderabad have shown evidence of living microbial cells. Unambiguous cells came examining micropore filters which the were recovered with use voltage sensitive lipophilic dyes that could detect presents active Clumps viable found all this technique, and conclusion was be consistent images obtained electron microscopy. Since...
Respiratory oscillations in continuous yeast cultures can be accounted for by cyclic energization of mitochondria, dictated the demands a temperature‐compensated ultradian clock with period 50 min. Inner mitochondrial membranes show both ultrastructural modifications and electrochemical potential changes. Electron transport components (NADH cytochromes c oxidase) redox state changes as organisms cycle between their energized de‐energized phases. These regular cycles are transiently perturbed...
Abstract A role for the cAMP‐dependent pathway in regulation of cell wall model yeast Saccharomyces cerevisiae has recently been demonstrated. In this study we report results a phenotypic analysis Candida albicans mutant, characterized by constitutive activation cAMP due to deletion PDE2 , gene encoding high cAMP‐affinity phosphodiesterase. Unlike wild‐type strains, mutant an increased sensitivity and membrane perturbing agents such as SDS CFW, antifungals amphotericin B flucytosine....
Abstract Morphometric measurements of the volume fractions (Vv) two prominent metal‐sequestering compartments, chloragosome granules and debris vesicles, were made on transmission electron micrographs chloragocytes in Dendrodrilus rubidus (Annelida: Oligochaeta: Lumbricidae) from one uncontaminated site three qualitatively quantitatively different metalliferous soils associated with disused Pb/Zn mines. We also examined relative alimentary wall attached chloragogenous tissue by light...
Abstract The Mexico City Prospective Study (MCPS) is a prospective cohort of over 150,000 adults recruited two decades ago from the urban districts Coyoacán and Iztapalapa in City. We generated genotype exome sequencing data for all individuals, whole genome 10,000 selected individuals. uncovered high levels relatedness substantial heterogeneity ancestry composition across Most sequenced individuals had admixed Native American, European African ancestry, with extensive admixture indigenous...
Guidelines recommend deferral of testing for symptomatic people with suspected coronary artery disease (CAD) and low pretest probability. To our knowledge, no randomized trial has prospectively evaluated such a strategy.
Trophozoites of the microaerophilic flagellate parasitic protozoon Giardia intestinalis have only a limited capacity to detoxify O2. Thus, when exposed controlled concentrations dissolved O2 >8 μM, they gradually lose their ability scavenge In washed cell suspension stirred under 10% air in N2 (equivalent 25 μM O2), inactivation O2-consuming system was complete after 3·5 h; during this period accumulation H2O2 (3 μmol per 106 organisms) and oxidation cellular thiols 16% initial level...
Pseudopollen is found on the labella of several species Maxillaria and formed by fragmentation uniseriate, multicellular, moniliform trichomes. The resultant component cells are rich in protein. Since flowers pseudopollen-forming generally lack nectar, it probable that pseudopollen gradually replaced nectar as pollinator reward. However, direct evidence for this hypothesis lacking. present paper examines labellar micromorphology five Brazilian assigned to M. discolor alliance. two these...
Here it is shown that the flagellated protozoon Giardia intestinalis, commonly regarded as an early branching eukaryote because of its lack mitochondria, has membraneous structures partition cationic, membrane-potential-sensitive fluorophore rhodamine 123. This organism also reduces a tetrazolium fluorogen at discrete plasma-membrane-associated sites. That these functions occur in distinctive specialized membrane systems supports growing evidence G. intestinalis may not be primitive, but...
• Background and Aims The labellar 'hairs' of some Cymbidium spp. are said to be thin-walled contain 'plasma', oil sugars it has long been speculated that they may function as food-hairs. However, the present authors' preliminary studies showed certain atypical papillae have a different role and, by reflecting light, speculum. purpose paper is test this hypothesis.
Understanding the relationships between accumulated metal speciation in cells and tissues of ecologically significant taxa such as earthworms will improve risk assessments. Synchrotron-based μ-focus X-ray spectroscopy was used to detect, localize, determine ligand-speciation Zn Pb thin sections two epigeic earthworm species collected from a Pb/Zn-mine soil. The findings indicated that partition predominantly typical hard acids (i.e., strong affinities for O-donors) within liverlike...