- Genetic Mapping and Diversity in Plants and Animals
- Genetic and phenotypic traits in livestock
- Genetics and Plant Breeding
- Plant and animal studies
- Insect and Arachnid Ecology and Behavior
- Asthma and respiratory diseases
- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Plant nutrient uptake and metabolism
- IL-33, ST2, and ILC Pathways
- Resilience and Mental Health
- Metabolism, Diabetes, and Cancer
- Genetic diversity and population structure
- Crop Yield and Soil Fertility
- High Altitude and Hypoxia
- Acupuncture Treatment Research Studies
- Childhood Cancer Survivors' Quality of Life
- Wheat and Barley Genetics and Pathology
- Cardiovascular and exercise physiology
- Neurobiology and Insect Physiology Research
- dental development and anomalies
- Allergic Rhinitis and Sensitization
- Animal Behavior and Reproduction
- Bipolar Disorder and Treatment
- Optical Imaging and Spectroscopy Techniques
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2024
Xiamen University
2020-2024
Northwest A&F University
2018-2024
Sichuan Agricultural University
2013-2023
Nanjing Medical University
2022-2023
Tianjin Medical University General Hospital
2023
Chinese Academy of Agricultural Sciences
2020-2023
Chengdu University
2023
Ningxia Medical University
2023
Northeast Agricultural University
2021-2023
Hyperuricemia (HUA) is a metabolic disease characterized by elevated serum uric acid (SUA).Empagliflozin, kind of sodium-glucose cotransporter 2 inhibitors, has recently emerged as new antidiabetic agent facilitating glucose excretion in urine.Moreover, there was evidence SUA reduction following treatment with empagliflozin addition to glycaemic control, while the molecular mechanisms remain unknown.To investigate potential mechanisms, model type diabetes (T2DM) HUA established combination...
Research has indicated that clinical serious disease may lead to posttraumatic growth (PTG). However, little is known about PTG among hemodialysis (HD) patients. The study examined the relationship resilience, rumination and Chinese HD 196 patients were recruited from a tertiary hospital in Northern city of China between 1 June 2015 30 May 2016. Patients surveyed using Posttraumatic Growth Inventory-Chinese version, Connor-Davidson Resilience Scale, Event Related Rumination Inventory....
The study presents a case of INOCA attributed to CMVD in 53-year-old male patient experiencing exertional angina, despite the absence significant coronary artery stenosis on angiography. presented with reversible myocardial ischemia detected by perfusion imaging, an ischemic area accounting for 12% left ventricular wall. Diagnostic tests revealed elevated index microcirculatory resistance (IMR = 46.3) and quantitative flow ratio (QFR 0.94), confirming CMVD. Genetic testing identified NOTCH1...
Background The burden of illness associated with bipolar disorder ( BD ) warrants early pre‐emption/prevention. Prediction models limited to psychiatric phenomenology have insufficient predictive power. Herein, we aimed evaluate whether the presence overweight/obesity is greater cognitive decline in individuals at high risk HR or ultra UHR for . Methods We conducted a retrospective analysis investigate moderational role body mass index BMI on measures function. Subjects between ages 8 and 28...
Increasing grain yield is a primary objective of maize breeding. Dissecting the genetic architecture furthers improvements to increase yield. Presented here an association panel composed 126 inbreds (AM126), which were genotyped by genotyping-by-sequencing (tGBS) method. We performed characterization and analysis related in panel. In total, 46,046 SNPs with minor allele frequency (MAF) ≥0.01 used assess diversity kinship AM126. The results showed that average MAF polymorphism information...
Allergic asthma is one of the inflammatory diseases, which has become a major public health problem. Qu zhi qiao (QZQ), dry and immature fruit Citrus paradisi cv. Changshanhuyou, various flavonoids with pharmacological properties. However, there knowledge gap on properties QZQ allergic asthma. Therefore, here, we explored efficacy mechanism total from (TFCH) We extracted purified TFCH conducted animal experiments using an Ovalbumin (OVA)-induced mice model. Bronchoalveolar lavage fluid...
Background: Suicide is a common and complex symptom of schizophrenia that may be related to clinical variables neurocognitive function. This study aimed investigate the associated correlates suicide attempts in Chinese middle-aged elderly inpatients with schizophrenia, including demographic characteristics cognitive level, which has not yet been reported. Methods: A total 426 were recruited for this study. Clinical symptoms evaluated using Positive Negative Syndrome Scale (PANSS)....
With the gradual deepening of understanding systemic health and quality life, factors affecting osteoarthritis (OA) are not limited to mechanical injury, metabolic abnormality, age obesity, etc., but circadian rhythm, which plays a non-negligible role in human daily life. The purpose this study was explore molecular mechanism chronic rhythm disturbance (CRD) inducing cartilage OA-like degeneration. Rats with anterior cruciate ligament excision transection (ACLT) were used establish...
Abstract Methyl-CpG-binding protein 2(MeCP2) is an important epigenetic regulatory factor that promotes many tumor developments, such as liver cancer, breast and colorectal cancer. So far, no pan-cancer analysis has been reported. Therefore, this study aims to explore pan-cancer's prognostic value, immune infiltration pattern, biological function. We used bioinformatics methods analyze the expression significance of MeCP2, relationship between MeCP2 clinicopathological parameters, genetic...
Abstract Grain chalkiness is an important index of rice appearance quality and negatively associated with processing eating quality. However, the genetic mechanism underlying formation largely unknown. To identify basis chalkiness, 410 recombinant inbred lines (RILs) derived from two representative indica varieties, Shuhui498 (R498) Yihui3551 (R3551), were used to discover quantitative trait loci (QTLs). The parental RILs grown in three locations China under controlled fertilizer application...
Maize grain size is the main factor determining yield. Dissecting genetic basis of maize may help reveal regulatory mechanism seed development and yield formation. In this study, two associated populations were used for genome-wide association analysis kernel length, width, thickness, hundred-kernel weight from multiple locations in AM122 AM180, respectively. Then, mapping was performed based on 6H90K SNP chip. A total 139 loci identified as with four traits p < 1 × 10-4 using models...
Objective: This report describes the design and printing of personalized nasal stents for cleft lip using 3-dimensional (3D) technology. Materials Methods: We used silicone rubber to make impressions, a 3D laser scanner obtain data, Dental SG resin cartridges as material. printed photosensitive printer. Results: placed in patients after surgery. They enabled adjustment good anastomosis, with low probability slipping from cavity. Conclusion: With this technique, we can provide support lip.
Cupping therapy is a promising method to cure or reduce the symptoms of some diseases including muscle pain/tendency/fatigue.Although applications cupping have thousand-year history in traditional Chinese medicine, therapeutic effect still questionable due lack scientific evidence and absence physiological observations.In our previous study, we utilized near-infrared spectroscopy (NIRS) assess concentration change surrounding site found significant elevation oxy-hemoglobin (HbO 2 ).To...
摘要: 以粳糯稻品种糯89-1与籼型重穗型杂交稻骨干恢复系蜀恢527杂交构建的籼粳交F7代RIL群体的169个家系为作图群体,构建了一张含105个微卫星(SSR)标记的分子连锁图谱。定位了水稻正季7个农艺性状的QTL 15个,分布在第1、第2、第3、第5、第6、第7、第10染色体上,LOD值介于2.10~7.51,贡献率3.77%~25.37%,其中贡献率10.0%以上的QTL 7个,单个性状的QTL 1~4个;定位了水稻再生季7个农艺性状的QTL 19个,分布在第1、第2、第3、第4、第5、第6、第7、第10染色体上,LOD值介于2.17~18.34,贡献率3.23%~37.66%,其中贡献率10.0%以上的QTL 7个,单个性状的QTL1~5个;定位了影响水稻再生力(最终再生率)的QTL 2个(qRa4,qRa5),分别在第4和第5染色体上,贡献率分别为8.17%和7.09%,加性效应分别为0.32和-0.39,贡献率和加性效应均较小,属微效基因。共检测到两季农艺性状QTL 36个,同一性状被重复检测的QTL...
Mandibular distraction osteogenesis (MDO) effectively improves airway obstruction in Pierre Robin syndrome (PRS) patients. However, whether or not early MDO is beneficial to the development of children still controversial. To observe influence PRS patient age at time on their development, authors retrospectively analyzed preoperative and postoperative body weight 41 with who underwent treatment from 2014 2016. The infants birth, first visit, surgery, distractor removal, palatoplasty surgery...
The performance of maize hybrids largely depend on two parental inbred lines. Improving lines using artificial selection is a key task in breeding programs. However, it important to elucidate the effects this Altogether, 208 from heterosis groups, named Shaan A and B, were sequenced by genotype-by-sequencing detect genomic changes under pressures. In addition, we completed genome-wide association analysis 121 identify candidate genes for ear morphology related traits. scan, B groups showed...