Alexandra Wagner

ORCID: 0000-0002-0443-6384
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About
Contact & Profiles
Research Areas
  • Civil and Structural Engineering Research
  • Folate and B Vitamins Research
  • Trace Elements in Health
  • Pluripotent Stem Cells Research
  • Iron Metabolism and Disorders
  • Bone health and osteoporosis research
  • Osteoarthritis Treatment and Mechanisms
  • Bone and Joint Diseases
  • Extracellular vesicles in disease
  • Physics and Engineering Research Articles
  • Photoacoustic and Ultrasonic Imaging
  • CRISPR and Genetic Engineering
  • Sensor Technology and Measurement Systems
  • Dermatologic Treatments and Research
  • Non-Invasive Vital Sign Monitoring
  • Salmonella and Campylobacter epidemiology
  • Nuclear Receptors and Signaling
  • German Literature and Culture Studies
  • Sperm and Testicular Function
  • Viral gastroenteritis research and epidemiology
  • Sirtuins and Resveratrol in Medicine
  • ECG Monitoring and Analysis
  • Blood disorders and treatments
  • Boron Compounds in Chemistry
  • Oral microbiology and periodontitis research

TechnoPhage (Portugal)
2022-2024

Comenius University Bratislava
2013-2022

Slovak Academy of Sciences
2022

Cancer Research Institute of the Slovak Academy of Sciences
2022

Saarland University
2008-2020

Ruhr University Bochum
2019-2020

Institute of Physics of the Slovak Academy of Sciences
2017

RWTH Aachen University
2016

Charité - Universitätsmedizin Berlin
2008

AO Foundation
2008

Resveratrol is a natural polyphenol studied for its possible protective properties in inflammatory bowel diseases. Moreover, it has been shown to interact with estrogen receptors. In the present study, we aimed investigate diverse effects of resveratrol on female and male mice DSS-induced colitis. Thirty-seven C57BL/6 (21 16 male) were divided into three groups each sex. The first group received pure water (CTRL). other two 1.5% dextran sulfate sodium (DSS) induce colitis from which one was...

10.1155/2017/8051870 article EN cc-by Gastroenterology Research and Practice 2017-01-01

Iron is very important element for functioning of the brain. Its concentration changes with aging brain or during disease. The aim our work was histological examination content ferritin and free iron (unbound) in cortex association Abeta plaques from their earliest stages accumulation amyloid plaque forming APP/PS1 transgenic mice. Light microscopy revealed onset formation at 8-monthage. Detectable traces no were found around this age, while rate elevated 13 months age. Ferritin accumulated...

10.33549/physiolres.934383 article EN cc-by-nc Physiological Research 2019-01-01

Hyperhomocysteinemia (HHCY) has been linked to fragility fractures and osteoporosis. Folate vitamin B(12) deficiencies are among the main causes of HHCY. However, impact these vitamins on bone health poorly studied. This study analyzed effect folate deficiency in rats. We used two groups rats: a control group (Co, n = 10) vitamin-deficient (VitDef, 10). VitDef animals were fed for 12 wk with folate- B(12)-free diet. Co received an equicaloric Tissue plasma concentrations homocysteine (HCY),...

10.1359/jbmr.081211 article EN Journal of Bone and Mineral Research 2008-12-02

Since the original study by Takahashi and Yamanaka in 2006, there have been significant advances field of induced pluripotent stem cells. However, to best our knowledge, all studies published date are based on ex vivo gene delivery subsequent reimplantation By contrast, reprogramming allows direct administration DNA encoding factors into target tissue. In previous we demonstrated beneficial effects Salmonella‑mediated oral genes colonic mucosa as a therapy for colitis. present study, effect...

10.3892/mmr.2014.2244 article EN Molecular Medicine Reports 2014-05-16

Abstract Background Diabetic Foot Ulcers (DFU) are a major complication in patients with diabetes and affect globally 170 million patients. Approximately 28% of infected DFU require amputation. foot infections (DFI) caused by persistent or multidrug resistant organisms threat to the outcome therapy. Infections mostly polymicrobial, pathogens include Staphylococcus aureus Pseudomonas aeruginosa. A promising new approach using phages may potentially be novel modality increase treatment...

10.1093/ofid/ofac492.1320 article EN Open Forum Infectious Diseases 2022-12-01

Dysbiosis of intestinal microbiota and hyperactive immune responses seem to be crucial for the uncontrolled inflammation in inflammatory bowel diseases (IBD). Modulation microbiome stimulation epithelium were suggested as therapeutic approaches. In this study, live attenuated dead bacterial cells Salmonella Typhimurium SL7207 - a widely used vector gene therapy administered DSS-induced colitis mice. C57BL/6 mice divided into four groups. The first group received pure water (CTRL). other...

10.1111/lam.12632 article EN Letters in Applied Microbiology 2016-08-08
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