- Nerve Injury and Rehabilitation
- Reconstructive Surgery and Microvascular Techniques
- Peripheral Nerve Disorders
- Nerve injury and regeneration
- Orthopedic Surgery and Rehabilitation
- Organ and Tissue Transplantation Research
- Neurofibromatosis and Schwannoma Cases
- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- Trauma Management and Diagnosis
- Silk-based biomaterials and applications
- Vascular Procedures and Complications
- Shoulder and Clavicle Injuries
- Urological Disorders and Treatments
- Spinal Cord Injury Research
- Elbow and Forearm Trauma Treatment
- Surgical site infection prevention
- Foot and Ankle Surgery
- Shoulder Injury and Treatment
- Anatomy and Medical Technology
- Spinal Fractures and Fixation Techniques
- Bone Tissue Engineering Materials
- Cleft Lip and Palate Research
- Rabies epidemiology and control
- Urologic and reproductive health conditions
Sun Yat-sen University
2009-2024
Sun Yat-sen Memorial Hospital
2024
First Affiliated Hospital of Jinan University
2017-2021
The First Affiliated Hospital, Sun Yat-sen University
2009-2016
First Affiliated Hospital of Henan University of Science and Technology
2016
Zero to Three
2014
Shandong University
2012
Background: Treatment of Bayne and Klug type III radial longitudinal deficiency with fibular epiphyseal transplantation in children has had limited success to date. The purpose this investigation was review the authors' results microvascular for deficiency. Methods: Between 2007 2009, four a mean age 4.3 years (range, 3.3 5.8 years) who underwent microsurgical reconstruction distal radius vascularized proximal transplantation, including physis, partial superior tibiofibular joint, variable...
Abstract In the study, functional recovery and relative comprehensive quality of life cases global brachial plexus treated with free functioning muscle transfers were investigated. Patients who received gracilis transfer between August 1999 October 2014 to reconstruct elbow flexion, wrist fingers extension recruited. The mean age patients was 26.36 (range, 16–42) years. period time from last follow-up 54.5 months 12–185 months). Muscle power, active range motion total recorded. SDS, SAS DASH...
The reconstruction of peripheral nerves has lately received great attention as many patients suffer from nerve injury every year around the world. However, damage to human cells different degrees irreversibility due a slow growth speed and low adhesion with surrounding tissues. In an effort overcome this challenge, we applied novel laminin (LN)-modified thiolated gellan gum (TGG) loaded factor (NGF) tissue engineering scaffold for facilitating neuronal stem cell proliferation via synergy...
Abstract Three-dimensional diffusion-weighted steady-state free precession (3D DW-SSFP) of high-resolution magnetic resonance has emerged as a promising method to visualize the peripheral nerves. In this study, application value 3D DW-SSFP brachial plexus imaging in diagnosis injury (BPI) was investigated. 33 patients with BPI were prospectively examined using MR neurography (MRN) plexus. Results MRN compared intraoperative findings and measurements electromyogram (EMG) or somatosensory...
The authors described a modified pathological classification (PC) of brachial plexus injury (BPI) and its magnetic resonance (MR) imaging characteristics. reliability diagnostic accuracy MR for detecting nerve was discussed. Between 2006 2010, 86 patients with BPI were managed surgically in our department. Their preoperative images surgical findings analyzed retrospectively. PC classified into five types: (I) root continuity (including Sunderland grade I-IV injury); (II) postganglionic...
Current research on bone marrow stem cell transplantation and autologous or xenogenic nerve for peripheral regeneration has mainly focused the repair of defects in rodents. In this study, we established a standardized experimental model radial primates evaluated effect injury. We repaired 2.5-cm lesions rhesus monkeys by autografts, acellular allografts, allografts seeded with cells. Five months after surgery, regenerated tissue was assessed function, electrophysiology, histomorphometry....
Arthroscopy-assisted closed reduction and percutaneous internal fixation is a minimally invasive technique for medial malleolus fracture treatment. The purpose of the study was to assess quality functional outcomes this technique.
Background . Large scalp defects, especially those complicated by calvarial titanium mesh exposure, or cerebrospinal fluid (CSF) leak, pose a challenge for the neurosurgeon and plastic surgeon. Here, we describe our experience of reconstructing complex defect with free flap transfer. Methods From October 2012 to September 2017, 8 patients underwent transfer reconstruction defects. Five presented tumor other 3 necrosis ulceration (2 plate exposure). Seven anterolateral thigh flaps one radial...
OBJECT Donor-side morbidity associated with contralateral C-7 (CC7) nerve transfer remains controversial. The purpose of this study was to evaluate functional deficits in the donor limb resulting from prespinal route CC7 transfer. METHODS A total 63 patients were included. Forty-one had undergone surgery at least 6 months previously and assigned one 2 groups based on duration postoperative follow-up. Group 1 (n = 21) consisted who between years previously, 20) more than previously. An...
<b>Background</b> This study describes a modified classification and management protocol for perineal soft tissue injuries associated with pelvic fractures. <b>Methods</b> A total of 11 patients open fractures were studied retrospectively. The classified into three types based on the area defect: type (urogenital zone), B (anal C (both urogenital anal zones). Each included following subclasses: A1 (without urethra injuries), A2 (with B1 anorectal B2 C1 B1), C2 C3 B2), C4 B2). was planned...
Brachial plexus injuries (BPI) are devastating events that frequently result in severe functional impairment of the upper extremity, and yet, present surgical reconstruction provides limited results. An animal model is an important tool to study peripheral nerve repair regeneration. Here, a passive traction apparatus allowed multidirectional force exerted on fixed forelimb was designed produce BPI rat noninvasive manner. Behavioral histological analyses were carried out assess suitability...
OBJECTIVE:In gracilis functioning free muscle transplantation, the limited caliber of dominant vascular pedicle increases complexity anastomosis and risk compromise.The purpose this study was to characterize results using a T-shaped for flow-through in transplantation brachial plexus injury.METHODS: The outcomes patients with injury who received either conventional end-to-end or from 2005 2013 were retrospectively compared.In group, comprised segment profunda femoris nutrient artery...
To establish a model for nerve grafts and determine the anatomic characteristics of brachial plexus in rhesus monkeys. Ten specimens were obtained from five monkey cadavers. Anatomic dissection was systemically performed. The length each root, trunk, division measured using Vernier caliper proximodistally. distributions suprascapular, axillary, musculocutaneous documented. monkeys included spinal nerves or roots C5, C6, C7, C8, T1 (80%, 8/10), with small contribution C4 root (20%, 2/10)...
The objective of this study was to provide anatomical data on modified contralateral C7 (cC7) nerve root transfers by dissecting and measuring the separable lengths root, trunk, divisions.Fifteen adult cervicothoracic specimens were dissected measured using Vernier calipers after exposing brachial plexus. Measurements included length from root-trunk-anterior division (and posterior division). epineuria at root-division-cord junctions opened until internal bundles fused together could not be...
OBJECTIVE:To investigate the feasibility of using free gracilis muscle transfer along with brachialis branch musculocutaneous nerve to restore finger and thumb flexion in lower trunk brachial plexus injury according an anatomical study a case report.METHODS: Thirty formalin-fixed upper extremities from 15 adult cadavers were used this study.The distance point at which originates midpoint humeral condylar was measured, as well length, diameter, course type nerve.An 18-year-old male who...
Objective: Functional reconstruction following severe traumatic muscle loss may cause problems for reconstructive surgeons. In such situations, functioning free transplantation (FFMT) represents an important alternative treatment option.Methods: The clinico-demographic characteristics of 11 patients receiving modified FFMT between 2005–2013 were retrospectively reviewed. strength, range joint motion (ROM), total active (TAM) the fingers, and Disability Arm Shoulder Hand (DASH) score adopted...
To evaluate the capacity and efficiency of human umbilical cord mesenchymal stem cells (HUCMSCs) to differentiate into neuron- like after induction with B27- supplemented serum- free medium.HUCMSCs at passage 4 were cultured for 14 days serum-containing medium (SCM) (group A), SCM 20 ng/mL nerve growth factor (NGF) 10 basic fibroblast (bFGF) B), serum-free (SFM) C), or SFM NGF bFGF. The culture changed every 3 neurospheres was observed using an inverted microscope. cell markers analyzed flow...
To analyze the effectiveness of proximal humeral internal locking system (Philos) plate for humerus fracture.Thirty-three patients with fracture were treated open reduction and fixation Philos between January 2009 2014. There 19 males 14 females, aged 23-89 years (mean, 56.6 years). The left side was involved in 15 cases, right 18 cases. injury causes included falling 20 cases traffic accident 13 All received X-ray CT scan three-dimensional reconstruction before operation. According to Neer...
Objective To investigate the quality of life on brachial plexus injury patients in crosssectional study method and acquire related data. analysis effect factors try to methods which help improve these patients. our knowledge, this is first that measures China. Methods Research participants completed Chinese version World Health Organization Quality Life Assessment-Bref (WHOQOL-BREF) 5-items International Index Erectile Dysfunction Questionnaire (IIEF-5) for male.Data were typed into computer...