A5017554590- Bone health and osteoporosis research
- Cardiac Imaging and Diagnostics
- Bone and Joint Diseases
- Advanced MRI Techniques and Applications
- Elasticity and Material Modeling
- Bone fractures and treatments
- Bone health and treatments
- Medical Imaging and Analysis
- Orthopaedic implants and arthroplasty
- Radiomics and Machine Learning in Medical Imaging
- Cardiac pacing and defibrillation studies
- Infectious Diseases and Tuberculosis
- Orthopedic Infections and Treatments
- COVID-19 diagnosis using AI
- Advanced X-ray and CT Imaging
- Hip and Femur Fractures
- Cardiovascular Function and Risk Factors
- Bone Tissue Engineering Materials
- Medical Imaging Techniques and Applications
- Spine and Intervertebral Disc Pathology
- Intracranial Aneurysms: Treatment and Complications
- Hip disorders and treatments
- Gout, Hyperuricemia, Uric Acid
- Hematological disorders and diagnostics
- Spinal Fractures and Fixation Techniques
Centre National de la Recherche Scientifique
2005-2025
Hôpital Lariboisière
2013-2025
Université Paris Cité
2011-2025
Assistance Publique – Hôpitaux de Paris
2012-2025
Hôpital américain de paris
2025
Inserm
2025
Institut Cardiovasculaire Paris Sud
2025
Hôpital Privé Jacques Cartier
2025
Siemens (France)
2025
Hôpital Fernand-Widal
2020-2024
Abstract Standardized particulate bone constructs, obtained by expanding autologous mesenchymal stem cells (MSCs) onto coral granules in vitro, were transplanted into long‐bone, critical‐size defects sheep. Control experiments also performed which grafts implanted. Defect cavities lined with a preformed vascularized membrane (induced temporarily inserting cement spacer for 6 weeks prior to construct implantation), served as mold keeping the engineered place. Radiographic, histological, and...
Objectives— To report an ovine model that can be used to evaluate the efficacy of bone substitutes for repair segmental diaphyseal defects. Study Design— Experimental study. Animals— Eleven 2‐year‐old Pré‐Alpes Sheep. Methods— Mid‐diaphyseal metatarsal defects (25 mm long) were stabilized by a dynamic compression plate over polymethylmethacrylate (PMMA) cement spacer, and external coaptation. The PMMA spacer was removed at 6 weeks incising encapsulating membrane. defect remained unfilled...
Large bone defects are still a challenge to orthopedic surgeons. In this study, massive defect with clinically relevant volume was efficiently reconstructed by transplanting an engineered in which mesenchymal stem cells (MSCs) expanded autologous serum (AS) were combined porous scaffold. the first step, we established that way MSCs distributed over scaffold affects ultimate bone-forming ability of transplant: constructs consisting natural coral and pseudo-periosteal layer surrounding implant...
Background There are conflicting data regarding the diagnostic performance of chest CT for COVID-19 pneumonia. Disease extent at has been reported to influence prognosis. Purpose To create a large publicly available set and assess prognostic value in Materials Methods This multicenter, observational, retrospective cohort study involved 20 French university hospitals. Eligible patients presented emergency departments hospitals between March 1 April 30th, 2020, underwent both thoracic reverse...
A cardiac MRI model incorporating the ischemic late gadolinium enhancement (LGE) parameters of extent, transmurality, location, and midwall LGE significantly outperformed traditional risk factors in predicting all-cause mortality participants with cardiomyopathy.
Background Multimodality imaging is essential for personalized prognostic stratification in suspected coronary artery disease (CAD). Machine learning (ML) methods can help address this complexity by incorporating a broader spectrum of variables. Purpose To investigate the performance an ML model that uses both stress cardiac MRI and CT angiography (CCTA) data to predict major adverse cardiovascular events (MACE) patients with newly diagnosed CAD. Materials Methods This retrospective study...
Abstract Background Late gadolinium enhancement (LGE) extent is the basis for risk stratification of hypertrophic cardiomyopathy (HCM) using cardiac magnetic resonance (CMR). LGE has been recently added in guidelines by European Society Cardiology (ESC) and American College (ACC), setting a threshold at ≥15% left ventricular mass. However, SCD become an uncommon event this population, mortality now mostly related to other phenotypes, such as stroke heart failure. While previous studies have...
Abstract Background Cardiac sarcoidosis (CS) is an underdiagnosed condition characterized by the formation of non-caseating granuloma in myocardium, potentially leading to arrhythmia, acute heart failure and sudden cardiac death. Early screening for diagnosis crucial optimize treatment delay progression. Hemodynamic forces (HDFs) are a measurement global force exchanged between blood volume myocardium assessed during magnetic resonance imaging (CMR), novel noninvasive parameter used detect...
Abstract Background Systemic sclerosis (SSc) is a connective tissue disease characterized by sustained inflammation, microvascular pathology changes and fibrosis. Cardiac comorbidities, particularly pulmonary arterial hypertension (PAH), are the leading cause of mortality among SSc patients. Early PAH diagnosis remains difficult. Cardiovascular magnetic resonance imaging (CMR) has emerged as great noninvasive tool to assess cardiological impact in SSc. Hemodynamic forces (HDF) measurement...
Abstract Background Although the presence and extent of ischaemic late gadolinium enhancement (LGE) as assessed by cardiovascular magnetic resonance (CMR) have emerged robust predictors outcomes in patients with cardiomyopathy (ICM), prognostic significance non-ischaemic LGE is not well established. Objective To assess impact a large cohort ICM reduced left ventricular ejection fraction (LVEF) undergoing CMR for myocardial viability. Methods Between 2008 2022, all consecutive referred...
Abstract Background Although the presence and extent of ischaemic late gadolinium enhancement (LGE) assessed by cardiovascular magnetic resonance (CMR) are robust predictors outcomes in patients with cardiomyopathy (ICM), prognostic significance other ischaemic-LGE parameters is not well established, no integrated score exists. Purpose This study aims to evaluate additional value a model that assesses granularity over traditional factors predicting mortality ICM patients. The includes...
The main objective of the study was to evaluate kinetics tophus volume measured with dual-energy CT (DECT) and ultrasound (US) in patients gout during their first 24 months treat-to-target (T2T) urate-lowering therapy. This a prospective, multicenter, 24-month longitudinal pilot including ULT-naïve US tophi. Clinical visits, DECT scans knees feet were performed at baseline, 6, 12 months. largest identified by chosen as index tophus. primary outcome change absolute relative from baseline all...
MR Angiography for the Long-Term Follow-Up of Dissecting Aneurysms Extracranial Internal Carotid ArteryHocine Djouhri1, Benoît Guillon2, Laurent Brunereau1, Claude Lévy1, Valérie Bousson1, Biousse2, Lionel Arrivé1 and Jean Michel Tubiana1Audio Available | Share
: To realize a tool for automatic segmentation and detection of lumbar disc degenerative disease fractures in MRI images using convolutional neural networks. We developed, on one hand, Picture Archiving Communication System (PACS) with DICOM viewer (Digital Imaging Communications Medicine) to extract training data implement 2 CNN networks dedicated the task other analysis simple pathologies hand.Two hundred forty-four scans T2 weighted sagittal were selected at university hospital Pasteur...