A5025756297- Muscle activation and electromyography studies
- Exercise and Physiological Responses
- Muscle metabolism and nutrition
- Cell Adhesion Molecules Research
- Cardiovascular and exercise physiology
- Per- and polyfluoroalkyl substances research
- Sports Performance and Training
- Cardiovascular Function and Risk Factors
- TGF-β signaling in diseases
- Renal Diseases and Glomerulopathies
- Dialysis and Renal Disease Management
- Children's Physical and Motor Development
- Infant Development and Preterm Care
- Cardiovascular Health and Disease Prevention
- Child Nutrition and Feeding Issues
- Health Systems, Economic Evaluations, Quality of Life
- Renal and related cancers
- Motor Control and Adaptation
- Healthcare cost, quality, practices
- Thermoregulation and physiological responses
- Breastfeeding Practices and Influences
- Organ Donation and Transplantation
- Blood Pressure and Hypertension Studies
- Air Quality and Health Impacts
- Cerebrovascular and Carotid Artery Diseases
Queensland University of Technology
2020-2023
Finis Terrae University
2016-2021
European Food Safety Authority
2012-2020
University of Florida
2013-2017
UNESCO
2016
Conseil de L'Europe
2016
Consejería de Educación, Universidades, Ciencia y Portavocía
2016
West Virginia University
1996-2015
National Institutes of Health Clinical Center
1995
National Cancer Institute
1995
The European Commission asked EFSA for a scientific evaluation on the risks to human health related presence of perfluoroalkyl substances (PFASs) in food. Based several similar effects animals, toxicokinetics and observed concentrations blood, CONTAM Panel decided perform assessment sum four PFASs: PFOA, PFNA, PFHxS PFOS. These made up half lower bound (LB) exposure those PFASs with available occurrence data, remaining contribution being primarily from short half-lives. Equal potencies were...
The European Commission asked EFSA for a scientific evaluation on the risks to human health related presence of perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic (PFOA) in food. Regarding PFOS PFOA occurrence, final data set available dietary exposure assessment contained total 20,019 analytical results (PFOS n = 10,191 9,828). There were large differences between upper lower bound due methods with insufficient sensitivity. CONTAM Panel considered estimates be closer true levels....
Dialysis patients are increasingly characterized by older age, multiple comorbidities, and shortened life expectancy. This study investigated whether the "surprise" question, "Would I be surprised if this patient died in next year?" identifies who at high risk for early mortality.
Proliferation of resident glomerular cells and the accumulation mesangial matrix are histologic abnormalities which observed in course many progressive diseases. We explored potential regulatory effects transforming growth factor-beta (TGF-beta) on these processes. found that cultured mouse endothelial, mesangial, epithelial as well isolated intact rat glomeruli possess high-affinity receptors for TGF-beta. also that, although TGF-beta consistently inhibited proliferation endothelial cells,...
This study investigated the effects of high-intensity resistance training on estimates motor neuron persistent inward current (PIC) in older adults. Seventeen participants (68.5 ± 2.8 yr) completed a 2-wk nonexercise control period followed by 6 wk training. Surface electromyographic signals were collected with two 32-channel electrodes placed over soleus to investigate unit discharge rates. Paired analysis was used calculate delta frequency (ΔF) as an estimate PIC amplitudes during 1)...
The mesangial cells, as part of their smooth muscle cell function, are actively involved in regulating glomerular hemodynamics. Their overlying endothelium is fenestrated; therefore, these cells directly exposed to plasma substances, including hormones such insulin and insulin-like growth factor I (IGF-I). These peptides may contribute the sclerosis cellular hyperplasia that characterize diabetic glomerulopathy. We report herein characterization receptors mitogenic effects IGF-I on mouse...
This study tested whether estimates of persistent inward currents (PICs) in the human plantar flexors would increase with level voluntary drive. High-density surface electromyograms were collected from soleus and gastrocnemius medialis 21 participants (29.2 ± 2.6 yr) during ramp-shaped isometric contractions to 10%, 20%, 30% (torque rise decline 2%/s 30-s duration) each participant's maximal torque. Motor units identified all contraction intensities included paired-motor unit analysis...
Animal-based measures (ABM) can be used effectively in the on-farm evaluation of broiler welfare relation to laws, codes practice, quality assurance schemes, management and also partly for ante-mortem inspection.Some ABM taken post-mortem at slaughterhouse.Non-animal-based when association between them outcome is strong they are more efficient than as a means safeguard welfare.They useful predictors broilers.The choice animalbased will depend upon specific objectives assessment.The full list...
Despite the terms’ often being used interchangeably, it has been suggested that perceptions of effort and exertion may differ. Eccentric (ECC) cycling provide a model exercise by which differences between these can be examined. Purpose: To examine compare during ECC concentric (CONC) at 4 intensities. Methods: Ten healthy male participants (mean [SD]: age = 29.8 [2.3] y) performed an incremental test for determination maximal aerobic power output, followed in randomized crossover design,...
The European Commission asked EFSA to assess information provided by the Spanish Ministry of Agriculture, Food and Environment, on toxicity free gossypol in relation use whole cotton seed feed for ruminants, particular dairy cows, and, if necessary, update previous opinion Panel Contaminants Chain (CONTAM) as an undesirable substance animal feed.Gossypol is a polyphenolic compound that exists racemic mixture (+)-gossypol (-)-gossypol isomers.It occurs or (protein-) bound forms...
Delta-9-tetrahydrocannabinol (D 9 -THC) is a naturally occurring psychoactive compound derived from the hemp plant Cannabis sativa.In 2015, EFSA established an acute reference dose (ARfD) of 1 lg/kg body weight (bw) for D -THC and assessed dietary exposure milk dairy products.This resulted at most 3% 13% ARfD adults toddlers, respectively.Following European Commission Recommendation 2016/2115 on monitoring presence in food issuing new mandate, human to -THC.'Standard' categories were used as...
We identified transforming growth factor-beta (TGF-beta)-binding proteins which are distinct from previously described TGF-beta receptors or TGF-beta-binding proteins. These migrate as 150- and 180-kDa 125I-TGF-beta 1 affinity-labeled complexes consistently co-expressed in A549, Mv1Lu, MG-63, BS-C-1 cells. They differ the types I, II, III their electrophoretic mobilities, lack of binding to 2, failure undergo marked down-regulation seen with following a 16-h incubation 1. The also recently...
We have identified two distinct classes of transforming growth factor-beta (TGF-beta)-binding proteins by affinity labeling rat glomeruli with 125I-TGF-beta 1 and 2. The first type consists a group that bind TGF-beta but do not When affinity-labeled were separated under nonreducing conditions, four prominent bands Mr values 320,000, 260,000, 170,000, 90,000 observed. Following reduction, the 320,000 170,000 yielded only 100,000 band, 260,000 complex 200,000, 100,000, 85,000, band migrated an...
We aimed to compare the cardiorespiratory, metabolic, and perceptual responses high- moderate-intensity eccentric cycling versus concentric in chronic obstructive pulmonary disease (COPD) patients. Ten patients with moderate COPD (forced expiratory volume 1 s (FEV ) = 68.6% ± 20.4% of predicted; 68.3 9.1 years) performed 30 min (CONC-M: 50% maximum workload; W max ), (ECC-M: high-intensity (ECC-H: 100% cycling. Average power output, oxygen consumption (V̇O 2 minute ventilation (VE),...
The world population is ageing. According to the United Nation's 2019 World Population Prospects, by 2050, one in six people will be over age 65, a striking increase from 11 2019. More than ever, we need elucidate age-related adaptations of neuromuscular system implement interventions which can maintain or improve function older adults. We rely on firing characteristics our spinal motoneurons produce force, and so, perform daily activities such as regulating pedal force while driving,...
Given the importance of exercise economy to endurance performance, we implemented two strategies purported reduce oxygen cost within a 4 week training camp in 21 elite male race walkers. Fourteen athletes undertook crossover investigation with beetroot juice (BRJ) or placebo (PLA) [2 d preload, 2 h pre-exercise + 35 min during exercise] 26 km walking at speeds simulating competitive events. Separately, 19 parallel group multi-pronged strategy (MAX; n = 9) involving chronic (2 w high...