Zhitong Zhang

ORCID: 0000-0002-0708-0096
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About
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Research Areas
  • Antibiotic Use and Resistance
  • Pneumonia and Respiratory Infections
  • Tuberculosis Research and Epidemiology
  • Robotic Locomotion and Control
  • Advanced Sensor and Energy Harvesting Materials
  • Patient Satisfaction in Healthcare
  • Medication Adherence and Compliance
  • Dermatology and Skin Diseases
  • Advancements in Transdermal Drug Delivery
  • Health Systems, Economic Evaluations, Quality of Life
  • Prosthetics and Rehabilitation Robotics
  • Gene Regulatory Network Analysis
  • Neuroscience and Neural Engineering
  • Chronic Disease Management Strategies
  • Geotechnical Engineering and Underground Structures
  • Contact Dermatitis and Allergies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Theoretical and Computational Physics
  • Additive Manufacturing and 3D Printing Technologies
  • Mobile Health and mHealth Applications
  • Human Pose and Action Recognition
  • Advanced oxidation water treatment
  • HIV/AIDS Research and Interventions
  • Healthcare Systems and Reforms
  • Pharmaceutical Practices and Patient Outcomes

Peking University
2021-2025

Shanghai CASB Biotechnology (China)
2025

Nanjing University of Chinese Medicine
2024

Guangzhou University of Chinese Medicine
2024

Jinggangshan University
2024

Public Health Ontario
2020-2024

University of Toronto
2020-2024

University of Wisconsin–Madison
2024

Beijing Advanced Sciences and Innovation Center
2023-2024

National University of Defense Technology
2018-2023

BackgroundInappropriate antibiotic prescribing contributes to the generation of drug resistance worldwide, and is particularly common in China. We assessed effectiveness an antimicrobial stewardship programme aiming reduce inappropriate paediatric outpatients by targeting providers caregivers primary care hospitals rural China.MethodsWe did a pragmatic, cluster-randomised controlled trial with 6-month intervention period. Clusters were township two counties Guangxi province China, which...

10.1016/s2214-109x(17)30383-2 article EN cc-by-nc-nd The Lancet Global Health 2017-11-05

Inappropriate antibiotic prescribing causes widespread serious health problems. To reduce of antibiotics in Chinese primary care to children with upper respiratory tract infections (URTIs), we developed an intervention comprising clinical guidelines, monthly review meetings, doctor-patient communication skills training, and education materials for caregivers. We previously evaluated our using unblinded cluster-randomised controlled trial (cRCT) 25 facilities across two rural counties. When...

10.1371/journal.pmed.1002733 article EN cc-by PLoS Medicine 2019-02-05

Highlights Polyimide-based flexible microneedle array (PI-MNA) electrodes realize high electrical/mechanical performance and are compatible with wearable wireless recording systems. The normalized electrode–skin interface impedance (EII) of the PI-MNA reaches 0.98 kΩ cm 2 at 1 kHz 1.50 10 Hz, approximately 1/250 clinical standard electrodes. This is first report on study applied to long-term continuous monitoring for polysomnography. Abstract Microneedle (MNA) an effective solution achieve...

10.1007/s40820-022-00870-0 article EN cc-by Nano-Micro Letters 2022-06-14

Microneedles, especially hollow microneedles (HMNs), play an important role in drug delivery, but most of the current HMNs are manufactured based on silicon microfabrication (lithography, etching, etc.), which slightly conservative due to lack low-cost, batch-scale and customized preparation approach, for with flexible substrate. For first time, we propose use a high-precision 3D printed master mold followed by dual-molding process different shapes, heights, inner outer diameters satisfy...

10.1002/btm2.10530 article EN cc-by Bioengineering & Translational Medicine 2023-05-02

Developing monolithic carbon-based catalyst with low cost, easy separation and high performance to degrade pollutants via PMS activation is crucial. In this work, a series of novel Me-CA catalysts based on biomass derived carbon aerogel were prepared by hydrothermal method using waste watermelon peel as raw material. Co-CA showed excellent activate for 2, 4-DCP degradation in different temperature water matrices. Different pollutants, such ciprofloxacin (CIP), bisphenol A (BPA),...

10.1016/j.ecoenv.2021.112381 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2021-06-03

Abstract Facial palsy (FP) profoundly influences interpersonal communication and emotional expression, necessitating precise diagnostic monitoring tools for optimal care. However, current electromyography (EMG) systems are limited by their bulky nature, complex setups, dependence on skilled technicians. Here we report an innovative biosensing approach that utilizes a PEDOT:PSS-modified flexible microneedle electrode array (P-FMNEA) to overcome the limitations of existing EMG devices. Supple...

10.1038/s41746-024-01002-1 article EN cc-by npj Digital Medicine 2024-01-15

Background: Overuse of antibiotics contributes to the development antimicrobial resistance.Objective: This study aims assess condition antibiotic use at health facilities county, township and village levels in rural Guangxi, China.Methods: We conducted a cross-sectional outpatient prescriptions 2014 for children aged 2–14 years with upper respiratory infections (URI). Twenty were randomly selected, including four county hospitals, eight hospitals clinics. Prescriptions extracted from...

10.1080/16549716.2017.1287334 article EN cc-by Global Health Action 2017-01-01

Weaning stress induces pigs oxidative stress, which decreases growth performance, causes intestinal damage, and increases diarrhea death in piglets. Microbe-derived antioxidants (MA) have an antioxidant immune-modulatory role, but the impacts of MA on structure function, inflammatory response weaned piglets are unclear. To elucidate whether can modulate response, barrier function impairment possible mechanisms its modulation, a total 60 DLY (a crossbreed Duroc, Landrance, Yorkshire) were...

10.1111/1750-3841.70064 article EN Journal of Food Science 2025-03-01

To evaluate the impact of national essential medicines scheme and zero-mark-up policy on antibiotic prescribing behaviour.In rural Guangxi, a natural experiment compared one county hospital which implemented with comparison did not. All outpatient inpatient records in 2011 2014 were extracted from two hospitals. Primary outcome indicator was rate (APR) among children aged 2-14 presenting outpatients primary diagnosis upper respiratory tract infection (URTI). We organised independent...

10.1111/tmi.12922 article EN Tropical Medicine & International Health 2017-06-30

Shandong Province has implemented the standardised treatment of multidrug-resistant tuberculosis (MDR-TB) supported by Global Fund. The study aimed to understand managements and delays patients with MDR-TB before initiating their treatments.All who had completed intensive phase from January 2010 May 2012 were interviewed using a structured questionnaire. Delays treatments analysed. Diagnosis delay is defined as period between having sputum smear results drug susceptibility test (DST)...

10.1111/tmi.12566 article EN Tropical Medicine & International Health 2015-07-14

Objective This study aims to assess whether a standard intervention package of cardiovascular disease (CVD) care was being delivered effectively, and if it associated with improved lifestyle biomedical indicators. Methods In rural China, we implemented pragmatic cluster randomized controlled trial for 12 months, at the township hospital level, compared usual care. Intervention case management guideline, training performance monitoring meeting patient support activities were designed fit...

10.1371/journal.pone.0183169 article EN cc-by PLoS ONE 2017-08-16

Abstract Background Tuberculosis (TB) is a major global health threat and the leading infectious disease cause of death worldwide. Access to retention in TB care remains challenge for patients, particularly those living rural remote settings. This qualitative study explored barriers facilitators accessing maintaining contact with services communities Xigaze (Shigatse) prefecture, Xizang Autonomous Region (Tibet Region), China from perspective persons impacted by TB. Methods We conduced...

10.1186/s40249-021-00906-4 article EN cc-by Infectious Diseases of Poverty 2021-09-20

Background: World Health Organisation recommends that electronic medication monitors (EMMs), a form of digital adherence technology, complement directly observed treatment (DOT) for tuberculosis (TB), as DOT is inconvenient and costly. However, existing evidence about their effectiveness inconclusive. We evaluated the comprehensive package based on EMMs among TB patients in Tibet.Methods: conducted this pragmatic, unblinded, multi-centre, individually-randomised, controlled, superiority...

10.2139/ssrn.4387313 preprint EN 2023-01-01
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