A5088085923- Heart Rate Variability and Autonomic Control
- Functional Brain Connectivity Studies
- Cardiac electrophysiology and arrhythmias
- ECG Monitoring and Analysis
- Mental Health Research Topics
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Cardiovascular Syncope and Autonomic Disorders
- Non-Invasive Vital Sign Monitoring
- Complex Systems and Time Series Analysis
- Soil and Land Suitability Analysis
- Smart Agriculture and AI
- Soil Geostatistics and Mapping
- Cardiac Health and Mental Health
- Blood Pressure and Hypertension Studies
- Neuroscience of respiration and sleep
- Cardiovascular Health and Disease Prevention
- Adenosine and Purinergic Signaling
- Neonatal and fetal brain pathology
- Mindfulness and Compassion Interventions
- Neuroscience and Neuropharmacology Research
- Vestibular and auditory disorders
- Cardiovascular and exercise physiology
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
Charité - Universitätsmedizin Berlin
2011-2025
Humboldt-Universität zu Berlin
2021-2025
Freie Universität Berlin
2021-2025
Deutsche Gesellschaft für Internationale Zusammenarbeit
2022-2025
Heidelberg University
1997-2024
University of Siegen
2024
University Medical Centre Mannheim
2024
University Hospital Heidelberg
2024
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2024
Ernst Abbe University of Applied Sciences Jena
2012-2022
To investigate cardiac autonomic dysfunction in patients with major depressive disorder (MDD). Research this area has faced several limitations because of the heterogeneity disease, influence medication, and methodological shortcomings.Participants were 75 suffering from an acute recurrent episode MDD matched controls. All participants assessed at baseline for linear nonlinear parameters heart rate variability, QT variability baroreflex sensitivity. Participants reassessed after 7 to 9 days...
Major depressive disorders (MDD) are associated with an increased risk for cardiovascular morbidity and mortality. Even if it is known that MDD accompanied by autonomic dysbalance sympathetic and/or reduced parasympathetic activity, to date only limited information available about the degree complexity of regulation. The aim this study was investigate influence on autonomous nervous system means linear nonlinear indices from heart rate blood pressure variability (HRV, BPV). From 57...
Older adults with concerns of falling show decrements gait stability under single (ST) and dual task (DT) conditions. To compare the effects a DT training integrating managing strategies for independent living older without concern about (CoF) to non-training control group on walking performance ST Single center parallel blind randomized controlled trial group-based interventions (DT-managing balance training) compared (Ninety-five adults; 71.5 ± 5.2 years). A progressive (12 sessions; 60...
Recent studies revealed cardiac autonomic dysfunction in patients with acute schizophrenia, which appears to be mainly related reduced vagal and increased sympathetic modulation. To understand the significance of function we extended these relatives patients. In this study, assessed modulation healthy first-degree schizophrenia (n = 36) investigate a putative genetic influence. Data were compared control subjects matched for age, gender, physical activity as well suffering from...
In addition to the sensitization of pain fibers in inflamed tissues, increased excitability spinal cord is an important mechanism inflammatory pain. Furthermore, neuronal has been suggested play a role modulating peripheral inflammation. This study was undertaken test hypothesis that actions proinflammatory cytokine tumor necrosis factor alpha (TNFalpha) add significantly both hyperalgesia and maintenance inflammation.Rats with antigen-induced arthritis (AIA) were treated intrathecally...
Abstract. Up-to-date digital soil resource information and its comprehensive understanding are crucial to supporting crop production sustainable agricultural development. Generating such through conventional approaches consumes time resources, is difficult for developing countries. In Ethiopia, the map that was in use qualitative, dated (since 1984), small scaled (1 : 2 M), which limit practical applicability. Yet, a large legacy profile dataset accumulated over emerging machine-learning...
Age has been identified as an independent risk factor for cardiovascular diseases. In addition, autonomic imbalance toward sympathetic preponderance shown to facilitate the occurrence of heart disease. Here, we aimed assess modulation parameters during normal ageing applying well-established linear and novel nonlinear parameters.Linear measures rate variability complexity well QT interval baroreflex sensitivity were obtained from a total 131 healthy, medication-free participants continuous...
Decreased heart rate variability (HRV) was shown for unmedicated patients with schizophrenia and their first-degree relatives, implying genetic associations. This is known to be an important risk factor increased cardiac mortality in other diseases. The interaction of cardio-respiratory function respiratory physiology has never been investigated the disease although it might closely related pattern autonomic dysfunction. We hypothesized that breathing rates reduced coupling acute would...
Maintaining and improving fitness are associated with a lower risk of premature death from cardiovascular disease. Patients schizophrenia known to exercise less have poorer health behaviors than average. Physical physiological regulation during tasks not been investigated date among patients schizophrenia. We studied autonomic modulation in stepwise exhaustion protocol 23 matched controls, using spirometry lactate diagnostics. Parameters physical capacity were determined at the aerobic,...
Besides the well-known cardiac risk factors for schizophrenia, increasing concerns have been raised regarding side-effects of antipsychotic medications. A bivariate analysis autonomic regulation, based on cardiovascular coupling, can provide additional information about heart rate (HR) and blood pressure regulatory patterns within complex interactions system. We introduce a new high-resolution coupling method (HRJSD) joint symbolic dynamics (JSD), which is characterized by three symbols,...
The autonomic nervous system (ANS) dysfunction has been well described in schizophrenia (SZ), a severe mental disorder. Nevertheless, the coupling between ANS and central brain activity not addressed until now SZ. interactions (CNS) need to be considered as feedback–feed-forward that supports flexible adaptive responses specific demands. For first time, best of our knowledge, this study investigates central–autonomic couplings (CAC) studying heart rate, blood pressure electroencephalogram...
The detection and quantification of coupling strength direction are important aspects for achieving a deeper understanding physiological regulatory processes in the field network physiology. Due to limitations established approaches, we developed directionality indices based on simple mathematical symbolization principles computational procedures that allow quick comprehensive underlying couplings. We introduced new index ( D HRJSD ) derived from pattern family density matrix High-Resolution...
Abstract Underlying biological mechanisms leading to the dramatically increased cardiac mortality in patients with schizophrenia (SCZ) are largely unknown. Cardiac autonomic dysfunction (CADF), which has been extensively described SCZ, represents an important physiological link cardiovascular disease (CVD). This study investigated prevalence of CADF SCZ using HRV across multiple domains (time and frequency, nonlinear dynamics, complexity measures, symbolic segmented Poincaré plot analysis)....
<title>Abstract</title> <italic>In a rapidly changing world, designing resilient farming systems is critical. Recent socio-ecological research hypothesized that the general resilience of system to disturbances related interplay between four key attributes—Agencies, Buffers, Connectivity, and Diversity (ABCD). However, relative importance these attributes in coping with multiple concurrent remains unclear. This study leverages longitudinal data, including biotic, abiotic socio-political...
We investigated to what degree tonic skin conductance levels (SCL) and cardiac autonomic dysfunction are interrelated in schizophrenia. Heart rate variability (HRV) SCL were simultaneously assessed 18 unmedicated patients controls matched for age, sex, weight, smoking habits. For comparison prior studies, phasic sympathetic responses (SPR) also recorded. Compared controls, had prolonged SPR latency reduced amplitude with a right-greater-than-left asymmetry, which was inversely correlated...
In industrialized countries with aging populations, heart failure affects 0.3-2% of the general population. The investigation 24 h-ECG recordings revealed potential nonlinear indices rate variability (HRV) for enhanced risk stratification in patients ischemic (IHF). However, long-term analyses are time-consuming, expensive, and delay initial diagnosis. objective this study was to investigate whether 30 min short-term HRV analysis is sufficient comparable IHF comparison h-HRV analysis. From...
Schizophrenia is a severe mental disorder associated with significantly increased cardiovascular mortality rate. However, the underlying mechanisms leading to this disease (CVD) are not fully known. Therefore, objective of study was characterize cardiorespiratory influence by investigating heart rate, respiration and causal strength direction coupling (CRC), based mainly on entropy measures. We investigated 23 non-medicated patients schizophrenia (SZ), comparing them age- gender-matched...
Summary Objective The need for alternative pharmacologic strategies in treatment of epilepsies is pressing about 30% patients with epilepsy who do not experience satisfactory seizure control present treatments. In temporal lobe ( TLE ) even up to 80% are pharmacoresistant, and surgical resection the ictogenic tissue only possible a minority patients. this study we investigate purinergic modulation drug‐resistant seizure‐like events SLE s) human cortex slices. Methods Layer V/ VI field...
The purpose of this exploratory study was to determine whether liver dysfunction can be generally classified using a wearable electronic nose based on semiconductor metal oxide (MOx) gas sensors, and the extent quantified. MOx sensors are attractive because their simplicity, high sensitivity, low cost, stability. A total 30 participants were enrolled, 10 them being healthy controls, with compensated cirrhosis, decompensated cirrhosis. We used three sensor modules nine different layers detect...