A5101602192- COVID-19 and Mental Health
- Pharmacological Effects of Natural Compounds
- Metabolism, Diabetes, and Cancer
- Morinda citrifolia extract uses
- Adipose Tissue and Metabolism
- Pancreatic function and diabetes
- Microbial Metabolism and Applications
- Health disparities and outcomes
- Circadian rhythm and melatonin
- Mental Health Research Topics
- Cancer Immunotherapy and Biomarkers
- Ferroptosis and cancer prognosis
- Mental Health Treatment and Access
- Dietary Effects on Health
- Digital Mental Health Interventions
- Ginseng Biological Effects and Applications
- Advanced Battery Materials and Technologies
- Pancreatic and Hepatic Oncology Research
- Radiomics and Machine Learning in Medical Imaging
- Psychosomatic Disorders and Their Treatments
- Insect and Pesticide Research
- Tryptophan and brain disorders
- Acupuncture Treatment Research Studies
- COVID-19 Pandemic Impacts
- COVID-19 epidemiological studies
China University of Geosciences
2022-2024
The Seventh Affiliated Hospital of Sun Yat-sen University
2020-2024
Sun Yat-sen University
2020-2024
Ningbo University
2023-2024
Xinjiang University
2023
South China Agricultural University
2020-2021
Weatherford College
2021
Sichuan University
2020-2021
State Council of the People's Republic of China
2020
West China Hospital of Sichuan University
2020
To examine the knowledge level, behaviors, and psychological status of Chinese population during COVID-19 pandemic, to explore differences between urban rural areas.We carried out a cross-sectional survey knowledge, behaviors related COVID-19, mental health in probability sample 3001 community residents 30 provinces or districts across China from February 16-23, 2020. Convenience sampling snowball were adopted. We used General Anxiety Disorder (GAD), 9-item Patient Health Questionnaire...
Recent reports support the involvement of hypothalamic orexigenic peptides in stimulating ethanol intake. Our previous studies have examined effects on peptide systems paraventricular nucleus (PVN) and identified a positive feedback loop which PVN peptides, such as enkephalin galanin, stimulate intake ethanol, turn, stimulates expression these peptides. Recently, orexin (OX), produced mainly by cells perifornical lateral hypothalamus (PFLH), has been shown to play an important role mediating...
AimsThis study explored the molecular and biologic mechanisms underlying association between circadian rhythm disorders (CRD) increased risk for hepatocellular carcinoma (HCC).BackgroundCRD are linked to HCC, but this limited.ObjectiveThe constructed validated a CRD related gene model as an independent prognostic factor providing insight into linking HCC identifying potential indicators efficacy of immunotherapy anticancer drugs. This helps provide important clues personalized treatment...
As the infection by <italic>Helicobacter pylori</italic> (<italic>H. pylori</italic>, HP) remains for a lifetime and may induce diseases such as gastric cancer, it is vital to detect diagnose it.
Abstract Background Caloric restriction (CR) has become increasingly attractive in the treatment of type 2 diabetes mellitus (T2DM) because common high-calorie diet and sedentary lifestyle. This study aimed to evaluate role CR T2DM further explore its potential molecular mechanisms. Methods Sixty male Sprague–Dawley rats were used this study. The model was induced by 8 weeks high-fat (HFD) followed a single dose streptozotocin injection (30 mg/kg). Subsequently, diabetic fed HFD at 28 g/day...
The related research of coronavirus disease 2019 (COVID-19) pandemic on the mental health community residents is still lacking. Here we reported status Chinese as well community's prevention and control during period COVID-19 further explored influencing factors status.In this cross-sectional study, convenience sampling snowball methods were adopted from February 16 to 23, 2020, included according inclusion exclusion criteria. Three questionnaires, including General Anxiety Disorder 7...
Abstract Objective The aim of this study was to evaluate the efficacy and safety modified fasting therapy, a retrospective conducted analyze changes in clinical indicators hospitalized patients. Methods A total 2054 patients were enrolled observational study. All participants underwent 7 days therapy. biomarkers, indicators, body composition measured before after fasting. Results therapy reduced weight, BMI, abdominal circumference, systolic blood pressure, diastolic pressure significantly....
Background: In patients with hepatocellular carcinoma (HCC), the tumor microenvironment (TME) is resistant to immunotherapy because of its specificity. It meaningful explore role macrophage, which one most abundant immune cells in TME, cellular communication and effect on prognosis HCC. Methods: Dimensionality reduction clustering single-cell RNA-seq data from GSE149614 dataset were carried out identify composition CellChat was used analyze between different cells. The specifically highly...
Clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses (HPAIVs) have caused outbreaks in poultry the world. Some of these acquired internal genes from other subtype (AIVs) such as H9 and H6 for generation novel reassortant continually circulated poultry. Here, we applied a duck-origin virus DK87 chicken-origin CK66 to assess biological characteristics H5N6 HPAIVs its pathogenesis ducks. A genetic analysis indicated that HA two were closely related H5 clade circulating Eastern Asia...
Background Using Minnesota Multiphasic Personality Inventory-2 (MMPI-2) clinical scales to evaluate symptoms in schizophrenia is a well-studied topic. Nonetheless, research focuses less on how these interact with each other. Aims Investigates the network structure and interaction of MMPI-2 between healthy individuals patients through Bayesian network. Method Data was collected from Wuhan Psychiatric Hospital March 2008 May 2018. A total 714 subjects were identified propensity score matching...
Abstract Background. Jiawei Ling Gui Zhu Gan Decoction (JW-LZD) is based on LingguiZhugan (LZD) and adds eight traditional Chinese medicines: Codonopsispilosula, Astragalus membranaceus, Yam, Epimedium, Morinda officinalis, TangerinePeel, Pinellia ternata Coix Seed, which can be used for the treatment of obesityin clinical. In this study, we determined molecular targets mechanismsinvolved in obesity through network pharmacological analysis, andmolecular docking technology. Material Methods....
Abstract BACKGROUND The related research of coronavirus disease 2019 (COVID-19) epidemic on mental health community residents is still lacking. Here we reported the status Chinese as well community’s prevention and control during period COVID-19, further explored influencing factors status. METHODS In this cross-sectional study, a convenience sampling snowball methods were adopted from February16 to February 23, 2020 included according inclusion exclusion criteria. Three questionnaires...
Abstract Background. Jiawei Ling Gui Zhu Gan Decoction (JW-LZD) is based on LingguiZhugan (LZD) and adds eight traditional Chinese medicines: Codonopsispilosula, Astragalus membranaceus, Yam, Epimedium, Morinda officinalis, TangerinePeel, Pinellia ternata Coix Seed, which can be used for the treatment of obesityin clinical. In this study, we determined molecular targets mechanismsinvolved in obesity through network pharmacological analysis, andmolecular docking technology. Material Methods....
Abstract Objective. Clinical studies have reported that moxibustion alleviates the side effects of chemotherapy, such as myelosuppression; however, its therapeutic mechanisms remain unclear. We investigated whether moxa cone (MCM) promotes recovery from chemotherapy-induced myelosuppression via hypothalamus-pituitary adrenal (HPA) axis. Methods. A model was established in mice using cyclophosphamide (CTX), and they were grouped into control, model, groups. In group, received MCM at ST36 for...
With the growth of world population, limited non-renewable energy sources, oil and coal mine are becoming increasingly exhausted. The long-term consumption fossil not only causes an crisis, but also makes ecological environmental problems more significant. Therefore, lithium batteries, as storage tool, have been studied by a number researchers due to their advantages such high specific energy, little pollution long cycle life. For secondary performance electrode materials affects development...
Abstract Background Caloric restriction (CR), as the only approved scientific method that can retard aging, has become more and attractive in treatment of type 2 diabetes mellitus (T2DM) due to increasingly common high calorie diet sedentary lifestyle. This study aimed evaluate its role T2DM further explored potential molecular mechanism. Methods A total 60 male SD rats were used this study. Diabetes model was induced by 8 weeks high-fat (HFD) followed a single dose streptozotocin injection...
Abstract Background: Jiawei Ling Gui Zhu Gan Decoction (JW-LZD) is based on Linggui Zhugan (LZD) and adds eight traditional Chinese medicines: Codonopsis pilosula, Astragalus membranaceus, Yam, Epimedium, Morinda officinalis, Tangerine Peel, Pinellia ternata Coix Seed , which can be used for the treatment of obesity in clinical. However, pharmacological mechanisms JW-LZD remain unclear. Methods: In this study, we determined molecular targets mechanismsinvolved through network analysis,...