A5060657924- Alzheimer's disease research and treatments
- Advanced Proteomics Techniques and Applications
- MicroRNA in disease regulation
- Cholinesterase and Neurodegenerative Diseases
- Neuroscience and Neuropharmacology Research
- Metabolomics and Mass Spectrometry Studies
- Machine Learning in Bioinformatics
- Food composition and properties
- Extracellular vesicles in disease
- Olfactory and Sensory Function Studies
- Genetic Mapping and Diversity in Plants and Animals
- Epilepsy research and treatment
- Biological Research and Disease Studies
- Plant tissue culture and regeneration
- Health, Environment, Cognitive Aging
- Vagus Nerve Stimulation Research
- Long-Term Effects of COVID-19
- S100 Proteins and Annexins
- Plant Gene Expression Analysis
- Neurogenesis and neuroplasticity mechanisms
- RNA Interference and Gene Delivery
- Pharmacological Effects and Toxicity Studies
- Crop Yield and Soil Fertility
- Protein Structure and Dynamics
- Bioinformatics and Genomic Networks
Universidad de Guadalajara
2015-2021
Instituto Politécnico Nacional
2013-2016
Center for Research and Advanced Studies of the National Polytechnic Institute
2011-2016
Centro de Investigación en Materiales Avanzados
2010
Dendrites and dendritic spines are dynamic structures with pivotal roles in brain connectivity have been recognized as the locus of long-term synaptic plasticity related to cognitive processes such learning memory. In neurodegenerative diseases, spine morphology alteration, shape density, affects functional characteristics leading dysfunction impairment. Recent evidence implicates a critical feature pathogenesis dementia, particularly Alzheimer's disease. The alteration their loss is...
Alzheimer's disease (AD) is the most common cause of dementia in elderly. AD brains are characterized by presence neurofibrillary tangles (NFTs) and neuritic plaques. NFTs constituted paired helical filaments, which structurally composed assembled hyperphosphorylated truncated tau polypeptides. To date, integral constituents remain unknown mainly due to high insolubility NFTs. The aim this study was identify tandem mass spectrometry, polypeptides contained both isolated laser capture...
Alzheimer׳s disease is one of the main causes dementia in elderly and its frequency on rise worldwide. It considered result complex interactions between genetic environmental factors, being many them unknown. Therefore, there a dire necessity for identification novel molecular players understanding this disease. In data article we determined protein expression profiles whole extracts from cortex regions brains patients with comparison to normal brain. We identified 721 iTRAQ-labeled...
Abstract Maize is one of the three staple foods in world. The white variety represents 60% maize importation with a world consumption 1125 million tons 2019/2020. Currently, new technologies could contribute to analysis this seed, supporting quality control and improvement. This study aims carry out morphological proteomic comparison between hybrid MR2008 its parental lines LUG03 CML491 through mass spectrometry bioinformatics analysis. Herein, we identified that 34.8% proteome differs from...
Alzheimer's disease (AD) is the most common form of dementia in elderly, affecting around 24.3 million people worldwide. As a consequence rapid demographic ageing, AD has become one severe progressive socio-economical and medical burdens facing countries all over world. brains are characterized by presence extracellular deposits amyloid-b-containing plaques intracellular neurofibrillary tangles (NFTs) composed paired helical filaments hyperphosphorylated Tau protein. considered to be result...
There are 36 million people worldwide diagnosed with dementia and it is expected that this number will double by year 2030. Alzheimer’s disease (AD) the most common type of in elderly, corresponding to approximately 60 80% all cases. AD linked a complex series events involving both genetic environmental factors. To gain further insights into complexity, we quantitatively analyzed proteome brains AD, using bottom-up proteomics approach, including iTRAQ-labeling two consecutive separation...
Alzheimer's disease (AD) is the most common form of dementia affecting around 24.3 million people worldwide. As a consequence rapid demographic ageing, AD has become one severe progressive socio-economical and medical burdens facing countries all over world. considered to be result complex events involving both genetic environmental factors. Initial changes in brain might occur decades prior onset clinical symptoms. brains are characterized by presence extracellular deposits amyloid-b...
Alzheimer's disease (AD) is the most common form of dementia affecting around 24.3 million people worldwide. As a consequence rapid demographic ageing, AD has become one severe progressive socio-economical and medical burdens facing countries all over world. considered to be result complex events involving both genetic environmental factors. Initial changes in brain might occur decades prior onset clinical symptoms. brains are characterized by presence extracellular deposits...
Alzheimer's disease (AD) is the commonest cause of dementia in elderly. Histopathologically AD brains are characterized by presence neurofibrillary tangles (NFTs), intracellular and extracellular (I-NFT E-NFT, respectively) neuritics plaques. Both structures represent dense accumulations abnormal insoluble filaments. NFTs formed paired helical filaments (PHFs), which structurally composed assembled tau protein. To date, integral constituents PHF remain unknown mainly due to highly...
Proteomics and some other cutting-edge technologies have generated information clusters in sequencing protein studies for plants, which can be used areas, such as food quality control, pharmacological allergens, characterizations of organisms biological agronomic vegetables. The following is a description the that found databases (DB) their interrelations with specialized DB, all references to describe protein. For this investigation we storage protein, Glutelin-2 (Zea mays), show...