A5018290790- Health Systems, Economic Evaluations, Quality of Life
- Hematopoietic Stem Cell Transplantation
- Lipoproteins and Cardiovascular Health
- Heart Failure Treatment and Management
- Healthcare Policy and Management
- Pharmaceutical Economics and Policy
- Cardiac pacing and defibrillation studies
- Renal Transplantation Outcomes and Treatments
- Mechanical Circulatory Support Devices
- Acute Lymphoblastic Leukemia research
- Transplantation: Methods and Outcomes
- Chronic Lymphocytic Leukemia Research
- Acute Myeloid Leukemia Research
- Cancer, Lipids, and Metabolism
- Atrial Fibrillation Management and Outcomes
- Multiple Myeloma Research and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Primary Care and Health Outcomes
- Venous Thromboembolism Diagnosis and Management
- Autoimmune and Inflammatory Disorders Research
- Organ Transplantation Techniques and Outcomes
- Acute Myocardial Infarction Research
- Cardiac Health and Mental Health
- Potassium and Related Disorders
Princess Margaret Cancer Centre
2023-2025
University of Toronto
2015-2025
Baylor University Medical Center
2019-2024
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2021-2024
Yale University
2016-2024
University Health Network
2023-2024
Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College
2024
The University of Texas Southwestern Medical Center
2022
Yale New Haven Hospital
2014-2022
Case Western Reserve University
2021
Introduction: To highlight the benefits and provide a framework for integrated multispecialty team involvement in management of hyperkalemia patients with heart failure kidney disease, to ensure that receive optimal medical therapy improve their clinical outcomes. Case presentation: This report highlights hypothetical “complex” case patient an acute decompensation who experiences following up-titration renin–angiotensin–aldosterone system inhibitor (RAASi) therapy. Two scenarios treatment...
Post-transplant cyclophosphamide (PTCy) is a promising graft-versus-host disease (GvHD) prophylaxis in haploidentical and matched unrelated donor hematopoietic stem cell transplantation (HSCT), but its role sibling (MSD) transplants remains unclear.We conducted retrospective study of 413 MSD-HSCT patients receiving peripheral blood (PBSC) grafts from January 2010 to 2023. Patients were categorized into four groups: Group I (CNI + MTX or MMF), II MMF ATG), III (PTCy ATG CNI), IV CNI MMF)....
ABSTRACT Pure red cell aplasia (PRCA) is a rare but significant complication following major ABO‐incompatible allogeneic hematopoietic stem transplantation (HSCT). The persistence of recipient B lymphocytes producing anti‐donor isohemagglutinins leads to reticulocytopenia and anemia, often resulting in transfusion dependence. Current treatment options for post‐HSCT PRCA are limited frequently yield suboptimal responses, complicating patient management. Herein, we report three cases...
Background: When presenting for atrial fibrillation (AF) ablation, women, compared with men, tend to have more nonpulmonary vein triggers and advanced disease. Whether this informs differences in AF ablation strategy is not well described. We aimed characterize complications by sex, using the Get With The Guidelines-AF registry. Methods: From registry feature, we included patients who underwent initial procedure between January 7, 2016, December 27, 2019. Patients were stratified based on...
Abstract Letermovir, a novel anti‐cytomegalovirus (CMV) agent acts by inhibiting the viral terminase complex and is approved for primary prophylaxis in CMV seropositive patients post allogeneic hematopoietic cell transplantation (HCT). The favorable efficacy safety profile make it an attractive option use as secondary at high‐risk reactivation. In this study, we report of letermovir after least one treated episode reactivation cohort 39 patients. Thirty two (82%) received anti‐thymocyte...
Background: Machine learning methods may complement traditional analytic for medical device surveillance. Methods and results: Using data from the National Cardiovascular Data Registry implantable cardioverter–defibrillators (ICDs) linked to Medicare administrative claims longitudinal follow-up, we applied three statistical approaches safety-signal detection commonly used dual-chamber ICDs that two propensity score (PS) models: one specified by subject-matter experts (PS-SME), other machine...
Abstract Introduction Pneumocystis jirovecii pneumonia (PJP) is a rare complication of hematopoietic stem cell transplantation (HSCT). Primary prophylaxis for 6–12 months post‐HSCT the standard approach. However, there no consensus regarding optimal duration prophylaxis. Methods We identified patients who developed PJP more than 1‐year post‐HSCT. All had previously received 12 was diagnosed based on clinical findings and detection P. in bronchoalveolar lavage (BAL) using polymerase chain...
Sudden cardiac death (SCD) is the most lethal manifestation of heart disease. In an Indian study SCDs contribute about 10% total mortality and SCD post ST elevation myocardial infarction (MI) constitutes for half deaths.
Hemophagocytic lymphohistiocytosis (HLH) is an aggressive hematological disorder caused by uncontrolled activation of cytotoxic T-cells (CTL), natural killer (NK) cells, and macrophages leading to hyperinflammation cytokine storm. The clinical course characterized high-grade fever, cytopenia, multiorgan dysfunction. HLH classified as either primary/familial or secondary, the latter being most often triggered infections, malignancies, autoimmune disorders. Viral infections are commonly known...