Manoj Chadha

ORCID: 0000-0002-5005-7799
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About
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Research Areas
  • Diabetes Management and Research
  • Diabetes Treatment and Management
  • Bone health and osteoporosis research
  • Diabetes and associated disorders
  • Parathyroid Disorders and Treatments
  • Hip and Femur Fractures
  • Pancreatic function and diabetes
  • Metabolism, Diabetes, and Cancer
  • Vitamin D Research Studies
  • Pituitary Gland Disorders and Treatments
  • Bone health and treatments
  • Diabetes Management and Education
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Bone Metabolism and Diseases
  • Pharmacology and Obesity Treatment
  • Lipoproteins and Cardiovascular Health
  • Cardiac, Anesthesia and Surgical Outcomes
  • Hormonal Regulation and Hypertension
  • Hormonal and reproductive studies
  • Celiac Disease Research and Management
  • Sexual Differentiation and Disorders
  • Digestive system and related health
  • Clinical practice guidelines implementation
  • Adrenal and Paraganglionic Tumors
  • Adrenal Hormones and Disorders

P. D. Hinduja Hospital and Medical Research Centre
2012-2024

Creative Commons
2023

Society for Vascular Surgery
2023

National Hospital
2011-2022

Dr. Balabhai Nanavati Hospital
2018

Bharti Hospital
2018

All India Institute of Medical Sciences
2017

Government Medical College
2017

Doncaster Royal Infirmary
2017

Topiwala National Medical College & BYL Nair Charitable Hospital
2013-2015

Hip fracture is a major public health problem. Earlier studies projected that the total number of hip will increase dramatically by 2050, and most occur in Asia. To date, only few provided updated projection, none them focused on projection Thus, it essential to provide up date prediction Asia, evaluate direct medical cost We 9 Asian Federation Osteoporosis Societies members using incidence rate population size. show from 1,124,060 2018 2,563,488 2.28-fold increase. This mainly due changes...

10.1016/j.afos.2018.03.003 article EN cc-by-nc-nd Osteoporosis and Sarcopenia 2018-03-01

Type 1 diabetes mellitus (T1DM) has been inconsistently associated with low bone mineral density (BMD) and increased fracture risk. 86 consecutive T1DM cases 140 unrelated age sex matched healthy nondiabetic controls were included in the study. After history examination, BMD body composition assessed by dual energy X-ray absorptiometry (DXA). Serum samples analyzed for calcium, phosphorus, albumin, creatinine, alkaline phosphatase, 25 (OH) vitamin D3, intact parathormone (PTH) levels (both...

10.1155/2013/397814 article EN cc-by Journal of Osteoporosis 2013-01-01

Guidelines for doctors managing osteoporosis in the Asia-Pacific region vary widely. We compared 18 guidelines similarities and differences five key areas. then used a structured consensus process to develop clinical standards of care diagnosis management improving quality care. Minimum assessment are needed (AP) inform practice (CPGs) improve present framework these describe its development. conducted comparative analysis existing CPGs AP using "5IQ" model (identification, investigation,...

10.1007/s00198-020-05742-0 article EN cc-by-nc Osteoporosis International 2021-01-27

The Asian-Indian phenotype of type 2 diabetes mellitus is uniquely characterized for cardio-metabolic risk. In the context implementing patient-centric holistic risk management as a priority, choice various combinations antidiabetic agents should be individualized. Combined therapy with two classes agents, namely, dipeptidyl peptidase 4 inhibitors and sodium-glucose co-transporter-2 inhibitors, target several pathophysiological pathways. wide-ranging clinical outcomes associated this...

10.1007/s13300-022-01219-x article EN cc-by-nc Diabetes Therapy 2022-03-25

The First Basal Insulin Evaluation (FINE) Asia study is a multinational, prospective, observational of insulin-naïve Type 2 diabetes mellitus (T2DM) patients in Asia, uncontrolled (A1c ≥ 8%) on oral hypoglycemic agents, designed to evaluate the impact basal insulin initiation.Basal was initiated with or without concomitant therapy and doses were adjusted individually. All treatment choices, including decision initiate insulin, at physician's discretion reflect real-life practice.Patients...

10.1111/j.1753-0407.2011.00137.x article EN Journal of Diabetes 2011-05-17

Conventional recommendation systems (RSs) are typically optimized to enhance performance metrics uniformly across all training samples, inadvertently overlooking the needs of diverse user populations. The disparity among various populations can harm model's robustness sub-populations due varying properties. While large language models (LLMs) show promise in enhancing RS performance, their practical applicability is hindered by high costs, inference latency, and degraded on long queries. To...

10.48550/arxiv.2501.04762 preprint EN arXiv (Cornell University) 2025-01-08

Primary hypothyroidism has been thought of as an inflammatory condition characterized by raised levels cytokines such C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α). Depression is also well known to occur in hypothyroidism. elevated cytokines. We planned study whether play important part linking these two conditions.(1) To know the prevalence depression overt due autoimmune thyroid disease. (2) correlate markers with occurrence depression. (3) effect...

10.4103/ijem.ijem_265_17 article EN cc-by-nc-sa Indian Journal of Endocrinology and Metabolism 2017-01-01

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by recalcitrant hypophosphatemia. Reports from the Indian subcontinent are scarce, with most being single center experiences involving few patients. Herein, we conducted retrospective analysis of 30 patients TIO diagnosed at three tertiary care hospitals in India. Patients persistent hypophosphatemia (despite correction hypovitaminosis D), normocalcemia, elevated alkaline phosphatase, low TmP/GFR and or...

10.1530/ec-18-0552 article EN cc-by-nc-nd Endocrine Connections 2019-02-13

Advances in the treatment of diabetes have led to an increase number injectable therapies, such as human insulin, insulin analogues, and glucagon-like peptide-1 analogues. The efficacy injection therapy depends on correct technique, among many other factors. Good technique is vital achieving glycemic control thus preventing complications diabetes. From patients' health-care providers' perspective, it essential guidelines understand injections techniques. abridged version First Indian Insulin...

10.4103/2230-8210.102929 article EN cc-by-nc-sa Indian Journal of Endocrinology and Metabolism 2012-01-01

Type 1 diabetes mellitus (T1DM) has a wide presence in children and high mortality rates. The disease, if left unmanaged, poses various challenges to the patient healthcare providers, including development of diabetic complications thus decreasing life expectancy affected child. T1DM include awareness disease that is very poor among general public also parents along with health care professionals. challenge lack can be met by increasing programs, conducting workshops for educators regarding...

10.4103/2230-8210.155339 article EN cc-by-nc-sa Indian Journal of Endocrinology and Metabolism 2015-01-01

We here report the demographic and clinical profile of patients enrolled in Indian Council Medical Research funded Registry people with diabetes India young age at onset (YDR) from 1 January 2000 to 31 July 2011.The YDR registry recruits all cases (newly diagnosed or treated) reporting on after diagnosis ≤25 years, residing within assigned geographical area centres. A baseline proforma was used obtain information details registration.The has 5546 (49.5% male; 50.5% female) youth 205 centres...

10.1111/pedi.12973 article EN Pediatric Diabetes 2019-12-30

Peripheral arterial disease (PAD) is one of the underdiagnosed and undertreated vascular diseases despite its significant burden in India. In India, etiological aspects, diagnostic approaches, treatment modalities, other preventive measures probably vary different regions. Therefore, this consensus was developed that provides a unified approach for physicians to effectively diagnose manage PAD consensus, we identify prevalence varies from 5% 25% Indian setting. Both atherosclerotic...

10.4103/1561-8811.383634 article EN cc-by-nc-sa Journal of Indian College of Cardiology 2023-08-01

A 65-year-old female at a district place with aches, pains and weakness of couple hour's duration visits an outpatient clinic. few investigations calcium vitamin D are advised in addition to blood glucose levels thyroid function test, she is do dual energy X-ray absorptiometry (DXA) scan, which didn't manage for next months as the same available bigger city, 3 h travel ultimately lands up hip fracture. The treated, discharged advice get DXA scan treatment osteoporosis deferred same. In...

10.4103/2230-8210.137482 article EN cc-by-nc-sa Indian Journal of Endocrinology and Metabolism 2014-01-01

Purpose: Osteoporosis is a global health disease. Increasing life span will add to the burden of osteoporosis, especially in postmenopausal women. The lifetime risk osteoporotic fractures 30% 40%. Fractures pose an extensive on healthcare resources. Therefore, early diagnosis osteoporosis necessary. Methods: In this review, we provide comprehensive approach current epidemiology, aspects, treatments and fracture management relation osteoporosis. Results: assessing patients, good medical...

10.4236/ojo.2022.124016 article EN Open Journal of Orthopedics 2022-01-01

The prevalence of autoimmune thyroid disease (AITD) is 10-12% in the general population worldwide. Among various disorders co-existing with AITD, concomitance celiac (CD) AITD results poor absorption medications and higher doses same. Institution gluten-free diet (GFD) this cohort helps reduce medication doses.To screen patients for presence autoimmunity (CA).A total 280 consecutive attending Out-patient Department a tertiary care hospital were screened tissue transglutaminase antibodies...

10.4103/2230-8210.172241 article EN cc-by-nc-sa Indian Journal of Endocrinology and Metabolism 2015-12-21

Abstract Summary This pilot audit explored how bone health is assessed patients with diabetes in diverse centres across Asia. Only 343 of 1092 (31%) audited had a assessment, 27% whom were diagnosed osteoporosis. Quality improvement strategies are needed to address gaps patient care this area. Purpose The Asia Pacific Consortium on Osteoporosis (APCO) Framework outlines clinical standards for assessing and managing A evaluated adherence standard 4, which states that should be conditions...

10.1007/s11657-024-01399-y article EN cc-by Archives of Osteoporosis 2024-06-11
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