- Ovarian function and disorders
- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Reproductive Biology and Fertility
- Intensive Care Unit Cognitive Disorders
- Reproductive System and Pregnancy
- Ovarian cancer diagnosis and treatment
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Pregnancy and preeclampsia studies
- Genetic Associations and Epidemiology
- Urinary Bladder and Prostate Research
- Anesthesia and Neurotoxicity Research
- Pelvic floor disorders treatments
- Urologic and reproductive health conditions
- Gestational Diabetes Research and Management
- Ocular Surface and Contact Lens
- Gastroesophageal reflux and treatments
- Cancer, Stress, Anesthesia, and Immune Response
- Music Therapy and Health
- Ectopic Pregnancy Diagnosis and Management
- Bioinformatics and Genomic Networks
- Reproductive Health and Contraception
- Ocular Diseases and Behçet’s Syndrome
Nanjing Medical University
2015-2025
Nanjing University
2014-2025
Nanjing General Hospital of Nanjing Military Command
2014-2025
Shanghai Jiao Tong University
2012-2024
Shenyang First People's Hospital
2024
Tongren Hospital
2021-2024
Kangda College of Nanjing Medical University
2021-2024
The First People’s Hospital of Lianyungang
2019-2024
Lianyungang Oriental Hospital
2024
Xuzhou Medical College
2024
This study aimed to identify key genes linked resistance a combination treatment regimen of bevacizumab and pemetrexed in non-small cell lung cancer (NSCLC) through bioinformatics analysis their associated pathways. Expression data from the Gene Omnibus (GEO) database (GSE154286) were analyzed. The differentially expressed (DEGs) between tissues sensitive resistant combined NSCLC identified. Ontology (GO) Kyoto Encyclopedia Genes Genomes (KEGG) enrichment was investigated, protein-protein...
Purpose To measure the change in visual acuity and vision-related quality of life patients with both age-related cataract bilateral macular degeneration (AMD) after surgery. Setting Department Ophthalmology, Shanghai General Hospital, Jiao Tong University, Shanghai, China. Design Prospective case series. Methods Patients advanced AMD who were diagnosed treated between January 2006 2012 enrolled. The had successful phacoemulsification foldable posterior chamber intraocular lens implantation....
Introduction Determining the causal relationship between polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM) holds significant implications for GDM prevention treatment. Despite numerous observational studies suggesting an association PCOS GDM, it remains unclear whether a definitive exists these two conditions which specific features of contribute to increased incidence GDM. Methods The (PCOS), its characteristic indices, was investigated using two-sample Mendelian...
This study investigates the prognostic value of apparent diffusion coefficient (ADC) in MRI for patients with acute posterior circulation stroke (PCS) undergoing endovascular therapy (EVT).
To demonstrate longitudinal postoperative vision-related quality of life and visual acuity changes after cataract surgery in advanced glaucoma patients.In total, 93 patients who underwent surgeries were collected from June 2010 through 2013 Shanghai First People's Hospital, Jiao Tong University, followed up for at least 3 months. Patients with glaucoma, here defined as near total cupping the optic nerve severe field loss within 10 degrees fixation, enrolled. A standard phacoemulsification...
Background This study aimed to evaluate and compare the utility values associated with diabetic retinopathy (DR) in a sample of Chinese patients ophthalmologists. Methods Utility were evaluated by both time trade-off (TTO) rating scale (RS) methods for 109 eligible DR 2 experienced Patients stratified Snellen best-corrected visual acuity (BCVA) better-seeing eye. The correlations between general vision-related health status measures analyzed. These compared data from two other studies....
Abstract Repeated implantation failure (RIF) greatly influences pregnancy rate after assisted reproductive technologies (ART) with elusive causes. Our study aimed to explore coagulation parameters in association RIF and establish a model predict the risk of Chinese women. Coagulation parameters, including prothrombin time (PT), thrombin (TT), activated partial (APTT), D-dimer (DD), fibrin degradation products (FDP), fibrinogen (FG), platelet aggregation induced by arachidonic acid (AA)...
Rhegmatenous retinal detachment (RRD) is one of the most serious complications after phacoemulsification combined with intraocular lens implantation surgery. It has been reported that vision-related quality life (VRQoL), as well visual acuity rapidly decreased when RRD developed. However, little known VRQoL in those patients anatomical re-attachment, especially whether or not higher than before cataract In this prospective case series study, we use Chinese-version low vision questionnaire...
To explore clinical indicators to predict perceived pain during second-eye phacoemulsification surgery in patients with bilateral cataracts.Shanghai General Hospital, China.A case‒control study and a prospective cohort study.Patients age-related cataract who underwent first-eye or uneventful were enrolled. Before surgery, ocular examination results, including vessel area density (VAD) skeleton (VSD), obtained by optical coherence tomography angiography of the iris performed. Patients...
ABSTRACT Research question Polycystic ovary syndrome (PCOS) is a common endocrine disorder with unclear etiology. Are there any genes that are pleiotropically or potentially causally associated PCOS? Design We applied the summary data-based Mendelian randomization (SMR) method integrating genome-wide association study (GWAS) for PCOS and expression quantitative trait loci (eQTL) data to identify were PCOS. performed separate SMR analysis using eQTL in whole blood. Results Although no showed...
Objective To evaluate the effects of sevoflurane on development posttraumatic stress disorder (PTSD) in rats and role hippocampal glycogen synthase kinase-3beta (GSK-3β).Methods Forty male Sprague-Dawley rats,weighing 250-300 g,aged 2 months,were randomly divided into 4 groups (n =10 each):control group (group C) ; PTSD P) S) lithium chloride (LiC1) + LS).Establishment model:the received 15 footshocks (1 mA,1 s shocks with a variable intershock interval 240-480 s) room A first day.On second...
Abstract Background Polycystic ovary syndrome (PCOS) poses a challenge in reproductive medicine, particularly understanding the role of hyperhomocysteinemia its pathogenesis, especially among women experiencing recurrent pregnancy loss (RPL). Objective We aimed to assess predictive value homocysteine (HCY) levels for outcomes with PCOS. Materials and Methods A consecutive series PCOS-diagnosed patients participated this prospective study. Pregnancy were collected prospectively. Women PCOS...
Background: Until recently, most enucleation techniques of the prostate were performed with application morcellator. We introduce a modified technique thulium laser non-morcellator approach, which is about incising and vaporizing remaining tissue instead Methods: A retrospective evaluation 223 patients undergoing ThuLEP from January 2014 to December 2015 was in our institution. One hundred five used morcellator while other 118 approach. All assessed International Prostate Symptom Score...