The intestinal tract is a typical radiosensitive tissue, and radiation rectal injury severe side effect that limits the prescribed dose in radiotherapy of abdominal pelvic region. Understanding post-irradiation kinetics Lgr5-positive stem cells crucial comprehending this adverse process. In study, we utilized Lgr5-EGFP knock-in mice expressing EGFP LGR5 antibody fluorescence staining wild-type mice. At state injury, qPCR analysis showed significant decrease expression level Lgr5 epithelial...

Abstract Mandibular reconstruction using computer-aided design and computer-assisted manufacturing (CAD/CAM) techniques has received recent attention. This technique theoretical advantages, although this approach can be commercially used in the limited area of world. The aim is to describe our experience in-house CAD/CAM guides situations which may present benefit region where commercial are unavailable. authors developed In-house for mandibular reconstructions with a free fibular flap....

Postoperative seroma is still the main complication after a latissimus dorsi (LD) flap procedure. The etiology of currently thought to comprise tissue fluids resulting from inflammatory reactions in affected caused by use monopolar electrocautery (EC). It possible that formation can be reduced using alternative devices such as PEAK PlasmaBlade (PPB), which provides atraumatic scalpel-like cutting precision while blade temperature remains close body temperature. subjects were 44 patients who...

Computer-aided design/computer-aided manufacturing (CAD/CAM) guides are now widely used in maxillofacial reconstruction. However, there few reports of CAD/CAM being for scapular flaps. The authors performed the secondary maxillary and orbital floor reconstruction using a free latissimus dorsi muscle, cutaneous tissue, flap designed techniques 72-year-old man who had undergone partial maxillectomy four years previously. patient diplopia, vertical dystopia eye position, large...

Summary: A defect of the central upper lip vermillion generally requires “like for like” reconstruction because this part can attract attention and has a unique structure color. In article, we report use labial artery-based horizontal long cross-lip flap reconstruction. first stage surgery, from lower starting at left commissure with vascular pedicle containing an inferior artery was raised transposed to defect. second stage, 12 days later, divided complete There were no postoperative...

Surgical osteotomy guides created by computer-aided design/computer-aided manufacturing (CAD/CAM) have been developed and are now widely used in maxillofacial reconstruction. However, there no standard procedures for dealing with an intraoperative change defect size. We report on a case which we our CAD/CAM to deal size maxillary planned the reconstruction using free fibula flap because of left sinus cancer 73-year-old man. In Japan, cannot use commercially supplied these not approved...

Computer-aided design/computer-assisted manufacturing (CAD/CAM) is now being evaluated as a preparative technique for maxillofacial surgery. Because this expensive and available in only limited areas of the world, we developed novel CAD/CAM surgical guide using an in-house approach. By CAD software, maxillary resection area cutting planes fibular angles are determined. Once decided, necessary faces extracted Boolean modifier. These superficial united to fit surface bones thickened stabilize...

A 64-year-old man was referred from a local clinic with chief complaint of cough. Computed tomography (CT) revealed mass comprising tumor in the right lower lobe and enlarged mediastinal lymph nodes, whole-body workup positron emission tomography-CT showed bilateral node enlargement cancerous pericarditis. Biopsy bronchoscopy confirmed histological findings small cell lung carcinoma. The clinical diagnosis extensive-stage cancer (ES-SCLC) confirmed, first-line treatment carboplatin,...

ABSTRACT Background The recipient vessel choice is very important when performing free‐flap breast reconstructions. Usually, the concomitant vein of artery anastomosed, and mismatches in diameter are occasionally observed. We consider thoracoepigastric (TEV) as a potential useful vein. use TEV not novel technique. It has been used by surgeons for anastomoses axillary region, but usually an anastomotic site second However, anatomical findings such diameter, its deficiency rate, influence on...

A deep inferior epigastric artery perforator (DIEP) flap has unique variations in the anatomy of vascular supply, and this idea been adapted to venous system. Venous system patterns, including connections between superficial vein (SDC) or across midline-crossing linking veins (MCLV), have gradually become recognized as a cause fat necrosis induration due congestion. Therefore, it is important select patients who are appropriate for transplantation by evaluating blood flow based on these...

The L\'evy walk, a type of random walk characterized by linear step lengths that follow power-law distribution, is observed in the migratory behaviors various organisms, ranging from bacteria to humans. Notably, walks with power exponents close two are frequently observed, though their underlying causes remain elusive. This study introduces simplified, abstract model designed produce inverse square walks, also known as Cauchy and explores conditions facilitate these phenomena. In our model,...

Problems in breast reconstruction with deep inferior epigastric perforator (DIEP) flaps include postoperative fat induration and necrosis. A resulting clinical symptom is palpable indurated tissue, but it difficult to measure the stiffness of transplanted tissues objectively at a site. The ability perform shear-wave elastography (SWE) was recently added some common ultrasonic echo devices, enabling objective three-dimensional measurements tissue stiffness. In this study, we measured DIEP...

Smooth interactions between talkers can be realized by transmitting and receiving mutual video images voices in remote communication. However, such communication, it is difficult to generate a sense of unity an interactive atmosphere because humans recognize screens as boundary the physical space. Therefore, essential develop communication system that share interaction-activated even if are places. In this study, we developed speech-driven avatar robot incorporating estimation model...

The optimum number of microvascular anastomoses for safe free tissue transfer is controversial. Although the case 2 venous versus 1 anastomosis has been argued, use an additional arterial not examined in detail.Twelve patients who underwent a flap were identified retrospectively from medical records undergoing reconstruction head and neck cancer. flaps limited to anterolateral thigh (ALT) flaps.All survived. Complications included thrombosis (n = 1), reexploration leakage 3). vascular...

BACKGROUND:Pharyngocutaneous fistulas are often difficult to treat because pharyngeal contents tend leak into the cervical layer causing wound infections or abscesses. If reconstruction with free flaps is difficult, pedicled pectoralis major an option. CASE REPORT:A 51-year-old male patient who had undergone radiation and chemotherapy for laryngeal cancer was scheduled total laryngectomy combined skin resection local tumor recurrence. Reconstruction a left deltopectoral (DP) flap performed....