A5100385698- Cancer, Lipids, and Metabolism
- Ferroptosis and cancer prognosis
- 2D Materials and Applications
- Cancer-related molecular mechanisms research
- Immune cells in cancer
- Graphene research and applications
- Neonatal Respiratory Health Research
- MXene and MAX Phase Materials
- Cancer, Hypoxia, and Metabolism
- Neuroscience of respiration and sleep
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- Prostate Cancer Diagnosis and Treatment
- Photodynamic Therapy Research Studies
- Lung Cancer Diagnosis and Treatment
- Congenital Diaphragmatic Hernia Studies
- Hippo pathway signaling and YAP/TAZ
- Tannin, Tannase and Anticancer Activities
- Pulmonary Hypertension Research and Treatments
- Circular RNAs in diseases
- Neuroscience and Neuropharmacology Research
- RNA modifications and cancer
- Natural Language Processing Techniques
- Topic Modeling
- Topological Materials and Phenomena
Nanjing University of Chinese Medicine
2016-2025
Ministry of Agriculture and Rural Affairs
2025
Shanghai Ocean University
2025
Southeast University
2025
Jiangsu Province Hospital
2016-2024
Inner Mongolia Medical University
2024
Hangzhou Dianzi University
2024
The University of Texas at Austin
2015-2023
Peking University First Hospital
2022-2023
Peking University
2022-2023
By using a comprehensive form of scanning tunneling spectroscopy, we have revealed detailed quasi-particle electronic structures in transition metal dichalcogenides, including the gaps, critical point energy locations, and their origins Brillouin zones. We show that single layer WSe2 surprisingly has an indirect gap with conduction band minimum located at Q-point (instead K), albeit two states are nearly degenerate. further observed rich dichalcogenides as function atomic spin–orbit...
Dehydrocostus lactone (Dehy), a natural sesquiterpene from Saussurea lappa Clarke, displays remarkable efficacy in treating cancer and gastrointestinal disorders. However, its anti-gastric (GC) effect remains poorly understood. Our study aimed to elucidate the anti-GC of Dehy putative mechanism. The was assessed with MTT, colony formation, wound healing transwell invasion assays. Cell apoptosis rate detected by Annexin V-FITC/PI binding assay. Network pharmacology analysis XF substrate...
Abstract The van der Waals interaction in vertical heterostructures made of two-dimensional (2D) materials relaxes the requirement lattice matching, therefore enabling great design flexibility to tailor novel 2D electronic systems. Here we report successful growth MoSe 2 on single-layer hexagonal boron nitride (hBN) Ru(0001) substrate using molecular beam epitaxy. Using scanning tunnelling microscopy and spectroscopy, found that quasi-particle bandgap hBN/Ru is about 0.25 eV smaller than...
Objective: To compare the efficacy and safety of robot-assisted laparoscopic radical prostatectomy (RARP) performed using KangDuo surgical robot system to da Vinci Si robotic in clinically localized prostate cancer (KD-RARP vs DV-RARP). Methods: A total 16 patients underwent extraperitoneal KD-RARP by a single experienced surgeon between May 2021 August 2021. The data were prospectively collected. most recent cases DV-RARP same selected from maintained database for comparison prevent...
Jianpi Yangzheng Xiaozheng decoction (JPYZXZ) is an empirical traditional Chinese medicine formula that has been reported to significantly prolong the survival of patients with advanced gastric cancer (GC). However, its underlying mechanism have not fully elucidated. The present work aims explore possible JPYZXZ on regulating GC progression. We firstly confirmed inhibitory effect in MKN74 cells and 615-strain mice, which was possibly mediated IL-6/JAK2/STAT3 pathway dependent PD-L1...
Prostate cancer (PCa) is the most common urological malignancy and second only to lung in incidence among men. Its prognosis varies widely due its heterogeneity. Research indicates that fatty acid metabolism may play a role tumor development. The gene expression profiles of PCa cell lines (GSE6919) GEO database were analyzed identify differentially expressed genes their significance relation progression-free interval. R package was employed assess overall survival clinicopathological...
ABSTRACT Tumor‐derived exosomes (TDEs) have emerged as vital biomarkers of multiple cancers. However, the diagnostic and stage‐predicting effects exosomal pyruvate kinase isoenzyme type M2 (PKM2) in peripheral blood its mechanism promoting gastric cancer (GC) remain unclear. Here, we analyzed plasma PKM2 216 samples collected from GC patients healthy donors (HD). The area under curve (AUC) demonstrated superior performance early diagnosis compared with that widely used clinical biomarkers....
Character-based dialogue (aka role-playing) enables users to freely customize characters for interaction, which often relies on LLMs, raising the need evaluate LLMs’ character customization capability. However, existing benchmarks fail ensure a robust evaluation as they only involve single category or limited dimensions. Moreover, sparsity of features in responses makes feature-focused generative both ineffective and inefficient. To address these issues, we propose CharacterBench, largest...
Background Non-invasive right ventricular (RV) myocardial work (RVMW) is the latest indicator used to assess RV function. Nevertheless, physiological determinants of RVMW have not been studied, and reference ranges for normal indices yet be established.Methods A total 263 healthy volunteers (median age: 34 years, males: 38%) were prospectively enrolled. analysed by an pressure-strain loop (RVPSL) in specific software.Results The lowest values males females 133 mmHg% 206 global index (RVGWI),...
Ovarian Carcinoma (OCa) is a high-mortality malignancy derived from female reproductive system. Increasing evidence has identified long non-coding RNAs (lncRNAs) as important regulators in OCa chemoresistance. In this study, we intended to explore the role of LINC01503 resistance carboplatin (CBP).Gene expression was measured by reverse transcription-quantitative PCR (RT-qPCR) cells. Western blot adopted detect protein levels GATA1, PD-L1, E-cadherin, N-cadherin, Vimentin, Bcl-2, Bax,...
The ability to engineer atomically thin nanoscale lateral junctions is critical lay the foundation for future two-dimensional (2D) device technology. However, traditional approach creating a heterojunction by direct growth of heterostructure two different materials constrains available band offsets, and it still unclear if large built-in potentials are attainable 2D materials. electronic properties semiconducting transition metal dichalcogenides (TMDs) not static, their exciton binding...
Bioactive lipids involved in the progression of various diseases. Nevertheless, there is still a lack biomarkers and relative regulatory targets. The lipidomic analysis samples from platinum-resistant gastric cancer patients expected to help us further improve our understanding it.
Background Previous evidence of an association between body mass index (BMI) and mortality in patients with diabetes was inconsistent. The BMI–mortality normal fasting glucose (NFG), impaired (IFG) prevalent is still unclear the Chinese population. Methods We analysed data for 17 252 adults from Rural Cohort Study during 2007–2008 followed 2013–2014. Participants were classified NFG, IFG according to baseline measurement values self-reported diabetes. Multivariable Cox proportional hazard...
After radical prostatectomy, the optimal length of postoperative catheterization time remains to be determined. This study investigates impact catheter removal on urinary continence and overactive bladder (OAB) symptoms after robot-assisted prostatectomy (RARP).Four hundred thirty-two consecutive patients underwent RARP by a single surgeon between Nov 2020 Oct 2021. Time was categorized into 7, 10, ≥14 days. Continence defined as no more than 1 pad used or 20 g urine leakage per 24 hours....