A5101654322- Coronary Interventions and Diagnostics
- Orthopaedic implants and arthroplasty
- Winter Sports Injuries and Performance
- Shoulder and Clavicle Injuries
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Bone fractures and treatments
- Trauma Management and Diagnosis
- Shoulder Injury and Treatment
- Hip disorders and treatments
- Gut microbiota and health
- Cardiac and Coronary Surgery Techniques
- Aldose Reductase and Taurine
- Sports Analytics and Performance
- RNA Research and Splicing
- Cardiac, Anesthesia and Surgical Outcomes
- Enhanced Recovery After Surgery
- Orthopedic Infections and Treatments
- Dietary Effects on Health
- Ideological and Political Education
- Educational Technology and Pedagogy
- Lower Extremity Biomechanics and Pathologies
- Spaceflight effects on biology
- Hip and Femur Fractures
- RNA and protein synthesis mechanisms
Hanzhong Central Hospital
2019-2025
Shanghai Ninth People's Hospital
2024
Shanghai Sixth People's Hospital
2023-2024
Shanghai Jiao Tong University
2023-2024
Wenzhou Medical University
2019-2024
Chinese People's Liberation Army
2024
Zhejiang Taizhou Hospital
2019-2021
Jiangsu Province Hospital
2020
Nanjing Medical University
2020
PLA 306 Hospital
2017
Non-alcoholic fatty liver disease (NAFLD) is regarded as a pandemic that affects about quarter of the global population. Recently, host-gut microbiota metabolic interactions have emerged distinct mechanistic pathways implicated in development NAFLD. Here, we report group gut microbiota-modified bile acids (BAs), hyodeoxycholic acid (HDCA) species, are negatively correlated with presence and severity HDCA treatment has been shown to alleviate NAFLD multiple mouse models by inhibiting...
Enteric infections are among the most common infectious diseases. The aim of this article was to track global trends in morbidity and mortality from enteric 204 countries or territories 1990 2019. Data were obtained Global Burden Disease 2019 study. Average annual percentage changes (AAPCs) age-standardized incidence rate (ASIR) (ASMR) calculated quantify infections. Age-period-cohort models used estimate 0 4 80 − 84 years (local drifts), period cohort effects between different...
Purpose Knee arthroplasty is an effective treatment for severe knee degeneration; however, periprosthetic joint infection (PJI) one of its serious complications. Single- and two-stage revision are common treatments, but few studies have compared single- PJI after arthroplasty. This study aimed to compare the reinfection reoperation rates through meta-analysis. Methods The review process was conducted according PRISMA guidelines. We searched PubMed, Medline, Embase Cochrane Central Register...
Abstract Fructose metabolism has emerged as a significant contributor to cancer cell proliferation, yet the underlying mechanisms and sources of fructose for cells remain incompletely understood. In this study, we demonstrate that can convert glucose into through process called AKR1B1 -mediated polyol pathway. Inhibiting endogenous production deletion dramatically suppressed glycolysis, resulting in reduced migration, inhibited growth, induction apoptosis cycle arrest. Conversely,...
Scope Adipose tissue macrophages (ATMs) are crucial in the pathogenesis of insulin resistance (IR). Intermittent fasting (IF) is an effective intervention for obesity. However, underlying mechanism by which IF improves IR remains unclear. Methods and results Male C57BL/6J mice fed chow‐diet high‐fat diet (HFD) 12 weeks, then randomized into ad libitum feeding or every other day 8 weeks. Markers ATMs expression uncoupling protein 1 (UCP‐1) determined. Gut microbiota bile acids (BAs) profiled...
Background Coronary chronic total occlusion (CTO) remains one of the most challenging lesion subsets in interventional cardiology, even with development medical device and operator expertise. This study was conducted to examine relationship between characteristics procedural success incidence in-hospital major adverse cardiac events (MACE) after percutaneous coronary intervention (PCI) for CTO. Methods Clinical angiographic data 1263 patients CTO who underwent PCI June 1995 December 2005...
Enterovirus 71 (EV71) is a significant causative agent of hand, foot, and mouth disease, with potential serious neurologic complications or fatal outcomes. The lack effective treatments for EV71 infection attributed to its elusive pathogenicity. Our study reveals that human plasmacytoid dendritic cells (pDCs), the main type I IFN-producing cells, selectively express scavenger receptor class B, member 2 (SCARB2) P-selectin glycoprotein ligand 1 (PSGL-1), crucial cellular receptors EV71. Some...
Background Failure of balloon catheter passing through the occluded segment accounts for 10%-15% all procedures during percutaneous coronary intervention (PCI) chronic total occlusion (CTO). We sought to investigate an original technique facilitating by multi-wire plaque crushing. Methods Between July 2000 and October 2007, 152 patients with 164 CTO lesions who had failed were treated crushing technique. The main process this was insert 1 or 2 wires along wire located in true lumen after...
Gravity plays an important role in normal tissue maintenance. The ability of stem cells to repair loss space through regeneration and differentiation remains largely unknown. To investigate the impact microgravity on blood vessel formation from pluripotent cells, we employed embryoid body (EB) model for vasculogenesis simulated by clinorotation. We first differentiated mouse embryonic into cystic EBs containing two germ layers then analyzed under observed that endothelial cell was slightly...
This study aimed to introduce a sternoclavicular joint (SCJ)-specific plate for the treatment of medial-end clavicle fracture and evaluate clinical radiological results this method.From January 2006 December 2020, 31 patients with displaced fractures were included in study, 8 accompanying SCJ dislocation. Abduction forward elevation shoulder, Visual Analogue Scale (VAS), American Shoulder Elbow Surgeons Score (ASES) used evaluation before index surgery at latest follow-up.After an average...
The treatment of traumatic sternoclavicular joint (SCJ) dislocation (SCJD) with internal fixation has been reported good short-term results, but data on its long-term results are scarce.Patients SCJD treated an SCJ-specific plate between January 2003 and 2018 were evaluated retrospectively. All implants routinely removed. Data from radiography, the American Shoulder Elbow Surgeons score, visual analogue scale abduction forward elevation shoulder collected before index surgery, at implant...
The traditional extended lateral approach for calcaneus fractures can provide sufficient exposure reduction, but complications are frequent. minimally invasive does limited damage to the soft tissue and its complication rate is low, provides surgical complicated fracture. Thus, an that could wide with less injury important.The bone flap approach, we proposed, involved same incision as approach. After incision, osteotomy was performed around bulged wall of without dissection tissue. free from...
OBJECTIVE To investigate the influence of total hip arthroplasty on changes spine pelvic parameters in patients with syndrome. METHODS From January 2013 to October 2014, 22 (26 hips) syndrome accompanied by necrosis femoral head, osteoarthritis and congenital dysplasia were treated arthroplasty. There 12 males 10 females an average age 58.4 years (range, 45 76 years). The course disease was 1.5 25 12.8 years. Before after operation, anteroposterior, full length radiographs both lower limbs,...